4JX5
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4JX4
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4LOC
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4LRS
| Crystal and solution structures of the bifunctional enzyme (Aldolase/Aldehyde dehydrogenase) from Thermomonospora curvata, reveal a cofactor-binding domain motion during NAD+ and CoA accommodation whithin the shared cofactor-binding site | 分子名称: | 4-hydroxy-2-oxovalerate aldolase, Acetaldehyde dehydrogenase, CHLORIDE ION, ... | 著者 | Fischer, B, Branlant, G, Talfournier, F, Gruez, A. | 登録日 | 2013-07-20 | 公開日 | 2013-09-04 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Crystal and solution structures of the bifunctional enzyme (Aldolase/Aldehyde dehydrogenase) from Thermomonospora curvata, reveal a cofactor-binding domain motion during NAD+ and CoA accommodation whithin the shared cofactor-binding site To be Published
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4LRT
| Crystal and solution structures of the bifunctional enzyme (Aldolase/Aldehyde dehydrogenase) from Thermomonospora curvata, reveal a cofactor-binding domain motion during NAD+ and CoA accommodation whithin the shared cofactor-binding site | 分子名称: | 4-hydroxy-2-oxovalerate aldolase, Acetaldehyde dehydrogenase, COENZYME A, ... | 著者 | Fischer, B, Branlant, G, Talfournier, F, Gruez, A. | 登録日 | 2013-07-20 | 公開日 | 2013-09-04 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystal and solution structures of the bifunctional enzyme (Aldolase/Aldehyde dehydrogenase) from Thermomonospora curvata, reveal a cofactor-binding domain motion during NAD+ and CoA accommodation whithin the shared cofactor-binding site To be Published
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4M6V
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4MFD
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4MFE
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4MIM
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4OV9
| Structure of isopropylmalate synthase binding with alpha-isopropylmalate | 分子名称: | (2S)-2-hydroxy-2-(propan-2-yl)butanedioic acid, ZINC ION, isopropylmalate synthase | 著者 | Zhang, Z, Wu, J, Wang, C, Zhang, P. | 登録日 | 2014-02-20 | 公開日 | 2014-08-20 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Subdomain II of alpha-isopropylmalate synthase is essential for activity: inferring a mechanism of feedback inhibition. J.Biol.Chem., 289, 2014
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4OV4
| Isopropylmalate synthase binding with ketoisovalerate | 分子名称: | 2-isopropylmalate synthase, 3-METHYL-2-OXOBUTANOIC ACID, ZINC ION | 著者 | Zhang, Z, Wu, J, Wang, C, Zhang, P. | 登録日 | 2014-02-20 | 公開日 | 2014-08-20 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Subdomain II of alpha-isopropylmalate synthase is essential for activity: inferring a mechanism of feedback inhibition. J.Biol.Chem., 289, 2014
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5KS8
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6E1J
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6NDS
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6KTQ
| Crystal structure of catalytic domain of homocitrate synthase from Sulfolobus acidocaldarius (SaHCS(dRAM)) in complex with alpha-ketoglutarate/Zn2+/CoA | 分子名称: | 2-OXOGLUTARIC ACID, COENZYME A, Homocitrate synthase, ... | 著者 | Suzuki, T, Tomita, T, Kuzuyama, T, Nishiyama, M. | 登録日 | 2019-08-28 | 公開日 | 2020-09-02 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Involvement of subdomain II in the recognition of acetyl-CoA revealed by the crystal structure of homocitrate synthase from Sulfolobus acidocaldarius. Febs J., 288, 2021
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7WTE
| Cryo-EM structure of human pyruvate carboxylase with acetyl-CoA in the intermediate state 2 | 分子名称: | ACETYL COENZYME *A, ADENOSINE-5'-TRIPHOSPHATE, Pyruvate carboxylase, ... | 著者 | Chai, P, Lan, P, Wu, J, Lei, M. | 登録日 | 2022-02-04 | 公開日 | 2022-11-09 | 最終更新日 | 2022-11-16 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA. Mol.Cell, 82, 2022
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7WTB
| Cryo-EM structure of human pyruvate carboxylase with acetyl-CoA | 分子名称: | 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ACETYL COENZYME *A, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Chai, P, Lan, P, Wu, J, Lei, M. | 登録日 | 2022-02-04 | 公開日 | 2022-11-09 | 最終更新日 | 2022-11-16 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA. Mol.Cell, 82, 2022
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7WTA
| Cryo-EM structure of human pyruvate carboxylase in apo state | 分子名称: | 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Pyruvate carboxylase, mitochondrial | 著者 | Chai, P, Lan, P, Wu, J, Lei, M. | 登録日 | 2022-02-04 | 公開日 | 2022-11-09 | 最終更新日 | 2022-11-16 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA. Mol.Cell, 82, 2022
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7WTD
| Cryo-EM structure of human pyruvate carboxylase with acetyl-CoA in the intermediate state 1 | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, COENZYME A, Pyruvate carboxylase, ... | 著者 | Chai, P, Lan, P, Wu, J, Lei, M. | 登録日 | 2022-02-04 | 公開日 | 2022-11-09 | 最終更新日 | 2022-11-16 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA. Mol.Cell, 82, 2022
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7WTC
| Cryo-EM structure of human pyruvate carboxylase with acetyl-CoA in the ground state | 分子名称: | 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ACETYL COENZYME *A, Pyruvate carboxylase, ... | 著者 | Chai, P, Lan, P, Wu, J, Lei, M. | 登録日 | 2022-02-04 | 公開日 | 2022-11-09 | 最終更新日 | 2022-11-16 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA. Mol.Cell, 82, 2022
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8HWL
| Human Pyruvate Carboxylase | 分子名称: | 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Pyruvate carboxylase, mitochondrial | 著者 | Liu, D.S, Su, J.Y. | 登録日 | 2022-12-30 | 公開日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (5.63 Å) | 主引用文献 | Human Pyruvate Carboxylase To Be Published
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8IH7
| AmnG-AmnH complex | 分子名称: | 4-hydroxy-2-oxovalerate aldolase, Acetaldehyde dehydrogenase, OXALATE ION, ... | 著者 | Su, D, Shi, Q.L. | 登録日 | 2023-02-22 | 公開日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | AmnG-AmnH complex To Be Published
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8GK8
| R21A Staphylococcus aureus pyruvate carboxylase | 分子名称: | 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ACETYL COENZYME *A, COENZYME A, ... | 著者 | Laseke, A.J, St.Maurice, M. | 登録日 | 2023-03-17 | 公開日 | 2023-08-30 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | 主引用文献 | Allosteric Site at the Biotin Carboxylase Dimer Interface Mediates Activation and Inhibition in Staphylococcus aureus Pyruvate Carboxylase. Biochemistry, 62, 2023
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8J7O
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