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4JX5
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BU of 4jx5 by Molmil
Structure of the carboxyl transferase domain from Rhizobium etli pyruvate carboxylase with pyruvate
分子名称: CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ...
著者Lietzan, A.D, St Maurice, M.
登録日2013-03-27
公開日2013-05-29
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献A Substrate-induced Biotin Binding Pocket in the Carboxyltransferase Domain of Pyruvate Carboxylase.
J.Biol.Chem., 288, 2013
4JX4
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BU of 4jx4 by Molmil
Structure of the carboxyl transferase domain from Rhizobium etli pyruvate carboxylase
分子名称: CHLORIDE ION, Pyruvate carboxylase, ZINC ION
著者Lietzan, A.D, St Maurice, M.
登録日2013-03-27
公開日2013-05-29
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.98 Å)
主引用文献A Substrate-induced Biotin Binding Pocket in the Carboxyltransferase Domain of Pyruvate Carboxylase.
J.Biol.Chem., 288, 2013
4LOC
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BU of 4loc by Molmil
Structure of the carboxyl transferase domain from Rhizobium etli pyruvate carboxylase with oxamate and biotin
分子名称: BIOTIN, CHLORIDE ION, GLYCEROL, ...
著者Lietzan, A.D, St.Maurice, M.
登録日2013-07-12
公開日2014-09-10
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献The role of biotin and oxamate in the carboxyltransferase reaction of pyruvate carboxylase.
Arch.Biochem.Biophys., 562C, 2014
4LRS
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BU of 4lrs by Molmil
Crystal and solution structures of the bifunctional enzyme (Aldolase/Aldehyde dehydrogenase) from Thermomonospora curvata, reveal a cofactor-binding domain motion during NAD+ and CoA accommodation whithin the shared cofactor-binding site
分子名称: 4-hydroxy-2-oxovalerate aldolase, Acetaldehyde dehydrogenase, CHLORIDE ION, ...
著者Fischer, B, Branlant, G, Talfournier, F, Gruez, A.
登録日2013-07-20
公開日2013-09-04
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Crystal and solution structures of the bifunctional enzyme (Aldolase/Aldehyde dehydrogenase) from Thermomonospora curvata, reveal a cofactor-binding domain motion during NAD+ and CoA accommodation whithin the shared cofactor-binding site
To be Published
4LRT
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BU of 4lrt by Molmil
Crystal and solution structures of the bifunctional enzyme (Aldolase/Aldehyde dehydrogenase) from Thermomonospora curvata, reveal a cofactor-binding domain motion during NAD+ and CoA accommodation whithin the shared cofactor-binding site
分子名称: 4-hydroxy-2-oxovalerate aldolase, Acetaldehyde dehydrogenase, COENZYME A, ...
著者Fischer, B, Branlant, G, Talfournier, F, Gruez, A.
登録日2013-07-20
公開日2013-09-04
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal and solution structures of the bifunctional enzyme (Aldolase/Aldehyde dehydrogenase) from Thermomonospora curvata, reveal a cofactor-binding domain motion during NAD+ and CoA accommodation whithin the shared cofactor-binding site
To be Published
4M6V
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BU of 4m6v by Molmil
Structure of the carboxyl transferase domain from Rhizobium etli pyruvate carboxylase with pyruvate and biocytin
分子名称: Biocytin, CHLORIDE ION, GLYCEROL, ...
著者Lietzan, A.D, St.Maurice, M.
登録日2013-08-11
公開日2014-09-10
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The role of biotin and oxamate in the carboxyltransferase reaction of pyruvate carboxylase.
Arch.Biochem.Biophys., 562C, 2014
4MFD
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BU of 4mfd by Molmil
Structure of the carboxyl transferase domain from Rhizobium etli pyruvate carboxylase with oxalate
分子名称: CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ...
著者Lietzan, A.D, St.Maurice, M.
登録日2013-08-27
公開日2013-11-13
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Insights into the carboxyltransferase reaction of pyruvate carboxylase from the structures of bound product and intermediate analogs.
Biochem.Biophys.Res.Commun., 441, 2013
4MFE
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BU of 4mfe by Molmil
Structure of the carboxyl transferase domain from Rhizobium etli pyruvate carboxylase with 3-hydroxypyruvate
分子名称: 3-HYDROXYPYRUVIC ACID, BIOTIN, CHLORIDE ION, ...
著者Lietzan, A.D, St.Maurice, M.
登録日2013-08-27
公開日2013-11-13
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Insights into the carboxyltransferase reaction of pyruvate carboxylase from the structures of bound product and intermediate analogs.
Biochem.Biophys.Res.Commun., 441, 2013
4MIM
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BU of 4mim by Molmil
Structure of the carboxyl transferase domain from Rhizobium etli pyruvate carboxylase with 3-bromopyruvate
分子名称: Bromopyruvate, CHLORIDE ION, GLYCEROL, ...
著者Lietzan, A.D, St.Maurice, M.
登録日2013-09-01
公開日2014-08-13
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Insights into the carboxyltransferase reaction of pyruvate carboxylase from the structures of bound product and intermediate analogs.
Biochem.Biophys.Res.Commun., 441, 2013
4OV9
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BU of 4ov9 by Molmil
Structure of isopropylmalate synthase binding with alpha-isopropylmalate
分子名称: (2S)-2-hydroxy-2-(propan-2-yl)butanedioic acid, ZINC ION, isopropylmalate synthase
著者Zhang, Z, Wu, J, Wang, C, Zhang, P.
登録日2014-02-20
公開日2014-08-20
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Subdomain II of alpha-isopropylmalate synthase is essential for activity: inferring a mechanism of feedback inhibition.
J.Biol.Chem., 289, 2014
4OV4
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BU of 4ov4 by Molmil
Isopropylmalate synthase binding with ketoisovalerate
分子名称: 2-isopropylmalate synthase, 3-METHYL-2-OXOBUTANOIC ACID, ZINC ION
著者Zhang, Z, Wu, J, Wang, C, Zhang, P.
登録日2014-02-20
公開日2014-08-20
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Subdomain II of alpha-isopropylmalate synthase is essential for activity: inferring a mechanism of feedback inhibition.
J.Biol.Chem., 289, 2014
5KS8
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BU of 5ks8 by Molmil
Crystal structure of two-subunit pyruvate carboxylase from Methylobacillus flagellatus
分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, MANGANESE (II) ION, PYRUVIC ACID, ...
著者Choi, P.H, Tong, L.
登録日2016-07-07
公開日2016-10-19
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献A distinct holoenzyme organization for two-subunit pyruvate carboxylase.
Nat Commun, 7, 2016
6E1J
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BU of 6e1j by Molmil
Crystal Structure of Methylthioalkylmalate Synthase (BjuMAM1.1) from Brassica juncea
分子名称: 2-isopropylmalate synthase, A genome specific 1, 4-(METHYLSULFANYL)-2-OXOBUTANOIC ACID, ...
著者Lee, S.G, Jez, J.M.
登録日2018-07-09
公開日2019-05-08
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.096 Å)
主引用文献Molecular Basis of the Evolution of Methylthioalkylmalate Synthase and the Diversity of Methionine-Derived Glucosinolates.
Plant Cell, 31, 2019
6NDS
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BU of 6nds by Molmil
Structure of an HMG-CoA lyase from Acenitobacter baumannii in complex with coenzyme A and 3-methylmalate
分子名称: 1,2-ETHANEDIOL, 3-hydroxy-3-methylglutaryl-CoA lyase, ACETATE ION, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2018-12-14
公開日2019-12-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structure of an HMG-CoA lyase from Acenitobacter baumannii in complex with coenzyme A and 3-methylmalate
to be published
6KTQ
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BU of 6ktq by Molmil
Crystal structure of catalytic domain of homocitrate synthase from Sulfolobus acidocaldarius (SaHCS(dRAM)) in complex with alpha-ketoglutarate/Zn2+/CoA
分子名称: 2-OXOGLUTARIC ACID, COENZYME A, Homocitrate synthase, ...
著者Suzuki, T, Tomita, T, Kuzuyama, T, Nishiyama, M.
登録日2019-08-28
公開日2020-09-02
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Involvement of subdomain II in the recognition of acetyl-CoA revealed by the crystal structure of homocitrate synthase from Sulfolobus acidocaldarius.
Febs J., 288, 2021
7WTE
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BU of 7wte by Molmil
Cryo-EM structure of human pyruvate carboxylase with acetyl-CoA in the intermediate state 2
分子名称: ACETYL COENZYME *A, ADENOSINE-5'-TRIPHOSPHATE, Pyruvate carboxylase, ...
著者Chai, P, Lan, P, Wu, J, Lei, M.
登録日2022-02-04
公開日2022-11-09
最終更新日2022-11-16
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA.
Mol.Cell, 82, 2022
7WTB
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BU of 7wtb by Molmil
Cryo-EM structure of human pyruvate carboxylase with acetyl-CoA
分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ACETYL COENZYME *A, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Chai, P, Lan, P, Wu, J, Lei, M.
登録日2022-02-04
公開日2022-11-09
最終更新日2022-11-16
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA.
Mol.Cell, 82, 2022
7WTA
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BU of 7wta by Molmil
Cryo-EM structure of human pyruvate carboxylase in apo state
分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Pyruvate carboxylase, mitochondrial
著者Chai, P, Lan, P, Wu, J, Lei, M.
登録日2022-02-04
公開日2022-11-09
最終更新日2022-11-16
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA.
Mol.Cell, 82, 2022
7WTD
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BU of 7wtd by Molmil
Cryo-EM structure of human pyruvate carboxylase with acetyl-CoA in the intermediate state 1
分子名称: ADENOSINE-5'-TRIPHOSPHATE, COENZYME A, Pyruvate carboxylase, ...
著者Chai, P, Lan, P, Wu, J, Lei, M.
登録日2022-02-04
公開日2022-11-09
最終更新日2022-11-16
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA.
Mol.Cell, 82, 2022
7WTC
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BU of 7wtc by Molmil
Cryo-EM structure of human pyruvate carboxylase with acetyl-CoA in the ground state
分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ACETYL COENZYME *A, Pyruvate carboxylase, ...
著者Chai, P, Lan, P, Wu, J, Lei, M.
登録日2022-02-04
公開日2022-11-09
最終更新日2022-11-16
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA.
Mol.Cell, 82, 2022
8HWL
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BU of 8hwl by Molmil
Human Pyruvate Carboxylase
分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Pyruvate carboxylase, mitochondrial
著者Liu, D.S, Su, J.Y.
登録日2022-12-30
公開日2024-01-31
実験手法ELECTRON MICROSCOPY (5.63 Å)
主引用文献Human Pyruvate Carboxylase
To Be Published
8IH7
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BU of 8ih7 by Molmil
AmnG-AmnH complex
分子名称: 4-hydroxy-2-oxovalerate aldolase, Acetaldehyde dehydrogenase, OXALATE ION, ...
著者Su, D, Shi, Q.L.
登録日2023-02-22
公開日2024-02-28
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献AmnG-AmnH complex
To Be Published
8GK8
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BU of 8gk8 by Molmil
R21A Staphylococcus aureus pyruvate carboxylase
分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ACETYL COENZYME *A, COENZYME A, ...
著者Laseke, A.J, St.Maurice, M.
登録日2023-03-17
公開日2023-08-30
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Allosteric Site at the Biotin Carboxylase Dimer Interface Mediates Activation and Inhibition in Staphylococcus aureus Pyruvate Carboxylase.
Biochemistry, 62, 2023
8J7O
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BU of 8j7o by Molmil
Human pyruvate carboxylase in BCCP-CTS state without BC
分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Pyruvate carboxylase, mitochondrial
著者Liu, D.S, Su, J.Y.
登録日2023-04-27
公開日2024-05-08
実験手法ELECTRON MICROSCOPY (3.83 Å)
主引用文献Human pyruvate carboxylase
To Be Published
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