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7SQ2
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Reprocessed and refined structure of Phospholipase C-beta and Gq signaling complex
分子名称: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3, ACETATE ION, CALCIUM ION, ...
著者Endo-Streeter, S.T, Sondek, J, Harden, T.K.
登録日2021-11-04
公開日2021-11-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Kinetic Scaffolding Mediated by a Phospholipase C-{beta} and Gq Signaling Complex
Science, 330, 2010
7T8T
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CryoEM structure of PLCg1
分子名称: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma, CALCIUM ION
著者Endo-Streeter, S, Sondek, J.
登録日2021-12-17
公開日2022-12-21
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.68 Å)
主引用文献CryoEM structure of PLCg1
To Be Published
7Z3J
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Structure of crystallisable rat Phospholipase C gamma 1 in complex with inositol 1,4,5-trisphosphate
分子名称: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, CALCIUM ION, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, ...
著者Pinotsis, N, Bunney, T.D, Katan, M.
登録日2022-03-02
公開日2022-07-20
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Characterization of the membrane interactions of phospholipase C gamma reveals key features of the active enzyme.
Sci Adv, 8, 2022
8EMV
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Phospholipase C beta 3 (PLCb3) in solution
分子名称: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3, CALCIUM ION
著者Falzone, M.E, MacKinnon, R.
登録日2022-09-28
公開日2023-05-24
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献G beta gamma activates PIP2 hydrolysis by recruiting and orienting PLC beta on the membrane surface.
Proc.Natl.Acad.Sci.USA, 120, 2023
8EMW
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Phospholipase C beta 3 (PLCb3) in complex with Gbg on liposomes
分子名称: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3, CALCIUM ION, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Falzone, M.E, MacKinnon, R.
登録日2022-09-28
公開日2023-05-24
最終更新日2024-09-25
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献G beta gamma activates PIP2 hydrolysis by recruiting and orienting PLC beta on the membrane surface.
Proc.Natl.Acad.Sci.USA, 120, 2023
8EMX
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Phospholipase C beta 3 (PLCb3) in complex with Gbg on lipid nanodiscs
分子名称: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3, CALCIUM ION, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Falzone, M.E, MacKinnon, R.
登録日2022-09-28
公開日2023-05-24
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献G beta gamma activates PIP2 hydrolysis by recruiting and orienting PLC beta on the membrane surface.
Proc.Natl.Acad.Sci.USA, 120, 2023
8T7C
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BU of 8t7c by Molmil
Crystal structure of human phospholipase C gamma 2
分子名称: 1,2-ETHANEDIOL, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2, CALCIUM ION
著者Chen, Y, Choi, H, Zhuang, N, Hu, L, Qian, D, Wang, J.
登録日2023-06-20
公開日2024-06-26
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献The crystal and cryo-EM structures of PLCg2 reveal dynamic inter-domain recognitions in autoinhibition
To Be Published
8UQO
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PLCb3-Gbg-Gaq complex on membranes
分子名称: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ...
著者Falzone, M.E, MacKinnon, R.
登録日2023-10-24
公開日2023-12-06
実験手法ELECTRON MICROSCOPY (3.37 Å)
主引用文献The mechanism of G alpha q regulation of PLC beta 3 -catalyzed PIP2 hydrolysis.
Proc.Natl.Acad.Sci.USA, 120, 2023
8UQN
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PLCb3-Gaq complex on membranes
分子名称: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ...
著者Falzone, M.E, MacKinnon, R.
登録日2023-10-24
公開日2023-12-06
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献The mechanism of G alpha q regulation of PLC beta 3 -catalyzed PIP2 hydrolysis.
Proc.Natl.Acad.Sci.USA, 120, 2023
9BCZ
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Chicken 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 (PLCZ1) in complex with calcium and phosphorylated threonine
分子名称: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ...
著者Edwards, M.M, Dong, A, Theo-Emegano, N, Seitova, A, Loppnau, P, Leung, R, Li, H, Ilyassov, O, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium, Structural Genomics Consortium (SGC)
登録日2024-04-10
公開日2024-05-15
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Chicken 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 (PLCZ1) in complex with calcium and phosphorylated threonine
To be published
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件を2024-10-30に公開中

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