7Z3J
Structure of crystallisable rat Phospholipase C gamma 1 in complex with inositol 1,4,5-trisphosphate
Summary for 7Z3J
| Entry DOI | 10.2210/pdb7z3j/pdb |
| Descriptor | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, CALCIUM ION, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, ... (5 entities in total) |
| Functional Keywords | hydrolase complex autoinhibited state, hydrolase |
| Biological source | Rattus norvegicus (Norway rat) More |
| Total number of polymer chains | 1 |
| Total formula weight | 136767.47 |
| Authors | Pinotsis, N.,Bunney, T.D.,Katan, M. (deposition date: 2022-03-02, release date: 2022-07-20, Last modification date: 2024-01-31) |
| Primary citation | Le Huray, K.I.P.,Bunney, T.D.,Pinotsis, N.,Kalli, A.C.,Katan, M. Characterization of the membrane interactions of phospholipase C gamma reveals key features of the active enzyme. Sci Adv, 8:eabp9688-eabp9688, 2022 Cited by PubMed: 35749497DOI: 10.1126/sciadv.abp9688 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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