8EMW
Phospholipase C beta 3 (PLCb3) in complex with Gbg on liposomes
Summary for 8EMW
Entry DOI | 10.2210/pdb8emw/pdb |
Related | 8EMV |
EMDB information | 28266 28267 |
Descriptor | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (4 entities in total) |
Functional Keywords | pip2 degradation, ip3 production, dag production, g protein signaling, hydrolase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 5 |
Total formula weight | 229140.19 |
Authors | |
Primary citation | Falzone, M.E.,MacKinnon, R. G beta gamma activates PIP2 hydrolysis by recruiting and orienting PLC beta on the membrane surface. Proc.Natl.Acad.Sci.USA, 120:e2301121120-e2301121120, 2023 Cited by PubMed: 37172014DOI: 10.1073/pnas.2301121120 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.5 Å) |
Structure validation
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