8UQO

PLCb3-Gbg-Gaq complex on membranes

Summary for 8UQO

• Entry DOI: 10.2210/pdb8uqo/pdb
• Related: 8UQN
• EMDB information: 42475 42476
• Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein subunit gamma, Guanine nucleotide-binding protein G(q) subunit alpha, ... (9 entities in total)
• Functional Keywords: plcb3, gbg, gaq, signaling protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 272256.14

Authors

Falzone, M.E.,MacKinnon, R. (deposition date: 2023-10-24, release date: 2023-12-06)

• Primary citation: Falzone, M.E.,MacKinnon, R.; The mechanism of G alpha q regulation of PLC beta 3 -catalyzed PIP2 hydrolysis.; Proc.Natl.Acad.Sci.USA, 120:e2315011120-e2315011120, 2023; PubMed: 37991948; DOI: 10.1073/pnas.2315011120

Experimental method

ELECTRON MICROSCOPY (3.37 Å)