8UQO
PLCb3-Gbg-Gaq complex on membranes
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, C) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 340 | 37416.9 | 2 | UniProt (P62873) Pfam (PF25391) | Homo sapiens (human) | Transducin beta chain 1 |
| 2 | C, D (D, G) | Guanine nucleotide-binding protein subunit gamma | polymer | 73 | 8015.3 | 2 | UniProt (G3V2N0) Pfam (PF00631) UniProt (by SIFTS) (P59768) | Homo sapiens (human) | |
| 3 | E (A) | Guanine nucleotide-binding protein G(q) subunit alpha | polymer | 355 | 41676.4 | 1 | UniProt (P50148) Pfam (PF00503) | Homo sapiens (human) | |
| 4 | F (Q) | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 | polymer | 1234 | 139104.7 | 1 | UniProt (Q01970) Pfam (PF17787) Pfam (PF22631) Pfam (PF00388) Pfam (PF00387) Pfam (PF00168) Pfam (PF08703) | Homo sapiens (human) | Phosphoinositide phospholipase C-beta-3,Phospholipase C-beta-3,PLC-beta-3 |
| 5 | G (A) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 6 | H (A) | TETRAFLUOROALUMINATE ION | non-polymer | 103.0 | 1 | Chemie (ALF) PubChem (5311325) | |||
| 7 | I (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) | |||
| 8 | J (Q) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) PubChem (271) | |||
| 9 | K (A) | water | water | 18.0 | 1 | Chemie (HOH) |
Sequence modifications
D, G: 0 - 71 (UniProt: G3V2N0)
A: 7 - 359 (UniProt: P50148)
Q: 10 - 1234 (UniProt: Q01970)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 5 | - | expression tag |
| Pro 6 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
| Pro 2 | - | expression tag |
| Ala 3 | - | expression tag |
| Met 4 | - | expression tag |
| Asp 5 | - | expression tag |
| Pro 6 | - | expression tag |
| Glu 7 | - | expression tag |
| Phe 8 | - | expression tag |
| Met 9 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 271645.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 610.6 | |
| All* | Total formula weight | 272256.1 |
