8UQO
PLCb3-Gbg-Gaq complex on membranes
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B, C | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 340 | 37416.9 | 2 | UniProt (P62873) Pfam (PF00400) In PDB | Homo sapiens (human) | Transducin beta chain 1 |
2 | D, G | Guanine nucleotide-binding protein subunit gamma | polymer | 73 | 8015.3 | 2 | UniProt (G3V2N0) Pfam (PF00631) UniProt (by SIFTS) (P59768) In PDB | Homo sapiens (human) | |
3 | A | Guanine nucleotide-binding protein G(q) subunit alpha | polymer | 355 | 41676.4 | 1 | UniProt (P50148) Pfam (PF00503) In PDB | Homo sapiens (human) | |
4 | Q | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 | polymer | 1234 | 139104.7 | 1 | UniProt (Q01970) Pfam (PF17787) Pfam (PF22631) Pfam (PF00388) Pfam (PF00387) Pfam (PF00168) Pfam (PF08703) In PDB | Homo sapiens (human) | Phosphoinositide phospholipase C-beta-3,Phospholipase C-beta-3,PLC-beta-3 |
5 | A | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
6 | A | TETRAFLUOROALUMINATE ION | non-polymer | 103.0 | 1 | Chemie (ALF) | |||
7 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
8 | Q | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
9 | water | water | 18.0 | 1 | Chemie (HOH) |
Sequence modifications
D, G: 0 - 71 (UniProt: G3V2N0)
A: 7 - 359 (UniProt: P50148)
Q: 10 - 1234 (UniProt: Q01970)
PDB | External Database | Details |
---|---|---|
Gly -1 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly 5 | - | expression tag |
Pro 6 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly 1 | - | expression tag |
Pro 2 | - | expression tag |
Ala 3 | - | expression tag |
Met 4 | - | expression tag |
Asp 5 | - | expression tag |
Pro 6 | - | expression tag |
Glu 7 | - | expression tag |
Phe 8 | - | expression tag |
Met 9 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 271645.6 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 610.6 | |
All* | Total formula weight | 272256.1 |