8UQO
PLCb3-Gbg-Gaq complex on membranes
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, C) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 340 | 37416.9 | 2 | UniProt (P62873) Pfam (PF00400) | Homo sapiens (human) | Transducin beta chain 1 |
| 2 | C, D (D, G) | Guanine nucleotide-binding protein subunit gamma | polymer | 73 | 8015.3 | 2 | UniProt (G3V2N0) Pfam (PF00631) UniProt (by SIFTS) (P59768) | Homo sapiens (human) | |
| 3 | E (A) | Guanine nucleotide-binding protein G(q) subunit alpha | polymer | 355 | 41676.4 | 1 | UniProt (P50148) Pfam (PF00503) | Homo sapiens (human) | |
| 4 | F (Q) | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 | polymer | 1234 | 139104.7 | 1 | UniProt (Q01970) Pfam (PF17787) Pfam (PF22631) Pfam (PF00388) Pfam (PF00387) Pfam (PF00168) Pfam (PF08703) | Homo sapiens (human) | Phosphoinositide phospholipase C-beta-3,Phospholipase C-beta-3,PLC-beta-3 |
| 5 | G (A) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 6 | H (A) | TETRAFLUOROALUMINATE ION | non-polymer | 103.0 | 1 | Chemie (ALF) | |||
| 7 | I (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 8 | J (Q) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 9 | K (A) | water | water | 18.0 | 1 | Chemie (HOH) |
Sequence modifications
D, G: 0 - 71 (UniProt: G3V2N0)
A: 7 - 359 (UniProt: P50148)
Q: 10 - 1234 (UniProt: Q01970)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 5 | - | expression tag |
| Pro 6 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
| Pro 2 | - | expression tag |
| Ala 3 | - | expression tag |
| Met 4 | - | expression tag |
| Asp 5 | - | expression tag |
| Pro 6 | - | expression tag |
| Glu 7 | - | expression tag |
| Phe 8 | - | expression tag |
| Met 9 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 271645.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 610.6 | |
| All* | Total formula weight | 272256.1 |
