PDB: 394 件ウェブページステータス検索Chemie searchBIRD

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2GJD	Distinct functional domains of Ubc9 dictate cell survival and resistance to genotoxic stress 分子名称: Ubiquitin-conjugating enzyme E2-18 kDa 著者 van Waardenburg, R.C, Duda, D.M, Lancaster, C.S, Schulman, B.A, Bjornsti, M.A. 登録日 2006-03-30 公開日 2006-07-04 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Distinct functional domains of ubc9 dictate cell survival and resistance to genotoxic stress. Mol.Cell.Biol., 26, 2006
8JVE	Identification and characterization of inhibitors covalently modifying catalytic cysteine of UBE2T and blocking ubiquitin transfer 分子名称: 1,2-ETHANEDIOL, 1-(3-methoxyphenyl)-1,2,3,4-tetrazole, Ubiquitin-conjugating enzyme E2 T 著者 Anantharajan, J, Baburajendran, N. 登録日 2023-06-28 公開日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Identification and characterization of inhibitors covalently modifying catalytic cysteine of UBE2T and blocking ubiquitin transfer. Biochem.Biophys.Res.Commun., 689, 2023
5EGG	Crystal structure of human ubiquitin-conjugating enzyme UBCH5C 分子名称: Ubiquitin-conjugating enzyme E2 D3 著者 Zhu, L, Li, H, Wu, F, Zhu, J. 登録日 2015-10-27 公開日 2016-11-02 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Structural analysis of recombinant human ubiquitin-conjugating enzyme UbcH5c Acta Pharm Sin B, 7, 2017
5D1K	Crystal Structure of UbcH5B in Complex with the RING-U5BR Fragment of AO7 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, E3 ubiquitin-protein ligase RNF25, ... 著者 Liang, Y.-H, Li, S, Weissman, A.M, Ji, X. 登録日 2015-08-04 公開日 2015-10-28 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Insights into Ubiquitination from the Unique Clamp-like Binding of the RING E3 AO7 to the E2 UbcH5B. J.Biol.Chem., 290, 2015
6GUM	Structure of the A.thaliana E1 UFD domain in complex with E2 分子名称: GLYCEROL, SAE2, SUMO-conjugating enzyme SCE1 著者 Liu, B, Lois, L.M, Reverter, D. 登録日 2018-06-19 公開日 2019-07-03 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.792 Å) 主引用文献 Structural insights into SUMO E1-E2 interactions in Arabidopsis uncovers a distinctive platform for securing SUMO conjugation specificity across evolution. Biochem.J., 476, 2019
7BOL	ubiquitin-conjugating enzyme, Ube2D2 分子名称: Ubiquitin-conjugating enzyme E2 D2 著者 Lee, S.O, Ryu, K.S, Chi, S.-W. 登録日 2020-03-19 公開日 2021-03-24 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.797 Å) 主引用文献 MUL1-RING recruits the substrate, p53-TAD as a complex with UBE2D2-UB conjugate. Febs J., 2022
3K9O	The crystal structure of E2-25K and UBB+1 complex 分子名称: Ubiquitin, Ubiquitin-conjugating enzyme E2 K 著者 Kang, G.B, Ko, S, Song, S.M, Lee, W, Eom, S.H. 登録日 2009-10-16 公開日 2010-09-08 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural Basis of E2-25K/UBB+1 Interaction for Neurotoxicity of Alzheimer Disease by Proteasome Inhibition To be Published
1ZUO	Structure of Human Ubiquitin-Conjugating Enzyme (UBCi) Involved in Embryo Attachment and Implantation 分子名称: BETA-MERCAPTOETHANOL, Hypothetical protein LOC92912 著者 Walker, J.R, Avvakumov, G.V, Cui, H, Newman, E.M, Mackenzie, F, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) 登録日 2005-05-31 公開日 2005-07-05 最終更新日 2012-11-28 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen. Mol Cell Proteomics, 11, 2012
3TGD	Crystal structure of the human ubiquitin-conjugating enzyme (E2) UbcH5b 分子名称: Ubiquitin-conjugating enzyme E2 D2 著者 Page, R.C, Amick, J, Misra, S. 登録日 2011-08-17 公開日 2011-08-31 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of the human ubiquitin-conjugating enzyme (E2) UbcH5b To be Published
6W7Z	RNF12 RING domain in complex with Ube2d2 分子名称: E3 ubiquitin-protein ligase RLIM, GLYCEROL, Ubiquitin-conjugating enzyme E2 D2, ... 著者 Middleton, A.J, Day, C.L. 登録日 2020-03-19 公開日 2020-05-20 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The RING Domain of RING Finger 12 Efficiently Builds Degradative Ubiquitin Chains. J.Mol.Biol., 432, 2020
5ULF	Crystal Structure of a UbcH5b~Ub conjugate 分子名称: GLYCEROL, Ubiquitin, Ubiquitin-conjugating enzyme E2 D2 著者 Middleton, A.J, Day, C.L, Wright, J.D. 登録日 2017-01-24 公開日 2017-06-07 最終更新日 2017-09-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Discovery of new non-covalent ubiquitin binding sites on UbcH5 To be published
2GRN	Crystal Structure of human RanGAP1-Ubc9 分子名称: Ran GTPase-activating protein 1, Ubiquitin-conjugating enzyme E2 I 著者 Yunus, A.A, Lima, C.D. 登録日 2006-04-24 公開日 2006-05-30 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Lysine activation and functional analysis of E2-mediated conjugation in the SUMO pathway. Nat.Struct.Mol.Biol., 13, 2006
3H8K	Crystal structure of Ube2g2 complxed with the G2BR domain of gp78 at 1.8-A resolution 分子名称: Autocrine motility factor receptor, isoform 2, Ubiquitin-conjugating enzyme E2 G2 著者 Kalathur, R.C, Das, R, Li, J, Byrd, R.A, Ji, X. 登録日 2009-04-29 公開日 2009-07-14 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Allosteric activation of E2-RING finger-mediated ubiquitylation by a structurally defined specific E2-binding region of gp78. Mol.Cell, 34, 2009
2BEP	Crystal structure of ubiquitin conjugating enzyme E2-25K 分子名称: BETA-MERCAPTOETHANOL, UBIQUITIN-CONJUGATING ENZYME E2-25 KDA 著者 Pichler, A, Knipscheer, P, Oberhofer, E, Van Dijk, W.J, Korner, R, Velgaard Olsen, J, Jentsch, S, Melchior, F, Sixma, T.K. 登録日 2004-11-29 公開日 2005-02-16 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Sumo Imodification of the Ubiquitin Conjugating Enzyme E2-25K Nat.Struct.Mol.Biol., 12, 2005
4DHI	Structure of C. elegans OTUB1 bound to human UBC13 分子名称: Ubiquitin thioesterase otubain-like, Ubiquitin-conjugating enzyme E2 N 著者 Wiener, R, Zhang, X, Wang, T, Wolberger, C. 登録日 2012-01-27 公開日 2012-02-22 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The mechanism of OTUB1-mediated inhibition of ubiquitination. Nature, 483, 2012
4NR3	Crystal Structure of a human Mms2/Ubc13 L121G mutant 分子名称: Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2 著者 Hodge, C.D, Edwards, R.A, Glover, J.N.M. 登録日 2013-11-26 公開日 2014-12-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.802 Å) 主引用文献 Stochastic gate dynamics regulate the catalytic activity of ubiquitination enzymes. J.Am.Chem.Soc., 136, 2014
4YII	Structure of an APC2-UBCH10 complex reveals distinctive cullin-RING ligase mechanism for Anaphase-promoting complex/Cyclosome 分子名称: Anaphase-promoting complex subunit 2, Ubiquitin-conjugating enzyme E2 C 著者 Brown, N.G, Cho, S.E, Schulman, B.A. 登録日 2015-03-02 公開日 2015-04-08 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.804 Å) 主引用文献 Crystal Structure of E2 Complex Proc.Natl.Acad.Sci.USA, 2015
4JQU	Crystal structure of Ubc7p in complex with the U7BR of Cue1p 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Coupling of ubiquitin conjugation to ER degradation protein 1, DI(HYDROXYETHYL)ETHER, ... 著者 Liang, Y.-H, Metzger, M.B, Weissman, A.M, Ji, X. 登録日 2013-03-20 公開日 2013-05-29 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 A Structurally Unique E2-Binding Domain Activates Ubiquitination by the ERAD E2, Ubc7p, through Multiple Mechanisms. Mol.Cell, 50, 2013
2A7L	Structure of the human hypothetical ubiquitin-conjugating enzyme, LOC55284 分子名称: Hypothetical ubiquitin-conjugating enzyme LOC55284, SODIUM ION 著者 Walker, J.R, Avvakumov, G.V, Xue, S, Newman, E.M, Mackenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) 登録日 2005-07-05 公開日 2005-09-06 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen. Mol Cell Proteomics, 11, 2012
7AHZ	Crystal structure of Western clawed frog MDM2 RING domain homodimer bound to UbcH5B-Ub 分子名称: CHLORIDE ION, E3 ubiquitin-protein ligase Mdm2, Polyubiquitin-B, ... 著者 Magnussen, H.M, Huang, D.T. 登録日 2020-09-25 公開日 2021-01-20 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Identification of a Catalytic Active but Non-Aggregating MDM2 RING Domain Variant. J.Mol.Biol., 433, 2021
6SQS	Crystal structure of cat phospho-Ser429 MDM2 RING domain bound to UbcH5B-Ub 分子名称: E3 ubiquitin-protein ligase Mdm2, Ubiquitin-40S ribosomal protein S27a, Ubiquitin-conjugating enzyme E2 D2, ... 著者 Magnussen, H.M, Ahmed, S.F, Huang, D.T. 登録日 2019-09-04 公開日 2020-05-06 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain. Nat Commun, 11, 2020
1X23	Crystal structure of ubch5c 分子名称: Ubiquitin-conjugating enzyme E2 D3 著者 Nakanishi, M, Teshima, N, Mizushima, T, Murata, S, Tanaka, K, Yamane, T. 登録日 2005-04-19 公開日 2005-05-03 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystal structure of ubch5c To be Published
6CYO	Crystal structure of human UBE2A (RAD6A) 分子名称: Ubiquitin-conjugating enzyme E2 A 著者 Ranzani, A.T, de Oliveira, J.F. 登録日 2018-04-06 公開日 2018-12-12 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Mechanistic insights revealed by a UBE2A mutation linked to intellectual disability. Nat. Chem. Biol., 15, 2019
5OJJ	Crystal structure of the Zn-bound ubiquitin-conjugating enzyme Ube2T 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, Ubiquitin-conjugating enzyme E2 T, ... 著者 Morreale, F.E, Testa, A, Chaugule, V.K, Bortoluzzi, A, Ciulli, A, Walden, H. 登録日 2017-07-21 公開日 2017-10-04 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Mind the Metal: A Fragment Library-Derived Zinc Impurity Binds the E2 Ubiquitin-Conjugating Enzyme Ube2T and Induces Structural Rearrangements. J. Med. Chem., 60, 2017
6MJ9	CRYSTAL STRUCTURE OF UBIQUITIN-CONJUGATING ENZYME FROM NAEGLERIA FOWLERI, APO FORM 分子名称: Ubiquitin-conjugating enzyme 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2018-09-20 公開日 2018-10-10 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 CRYSTAL STRUCTURE OF UBIQUITIN-CONJUGATING ENZYME FROM NAEGLERIA FOWLERI, APO FORM To Be Published

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