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2GJD
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BU of 2gjd by Molmil
Distinct functional domains of Ubc9 dictate cell survival and resistance to genotoxic stress
分子名称: Ubiquitin-conjugating enzyme E2-18 kDa
著者van Waardenburg, R.C, Duda, D.M, Lancaster, C.S, Schulman, B.A, Bjornsti, M.A.
登録日2006-03-30
公開日2006-07-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Distinct functional domains of ubc9 dictate cell survival and resistance to genotoxic stress.
Mol.Cell.Biol., 26, 2006
5EGG
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BU of 5egg by Molmil
Crystal structure of human ubiquitin-conjugating enzyme UBCH5C
分子名称: Ubiquitin-conjugating enzyme E2 D3
著者Zhu, L, Li, H, Wu, F, Zhu, J.
登録日2015-10-27
公開日2016-11-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Structural analysis of recombinant human ubiquitin-conjugating enzyme UbcH5c
Acta Pharm Sin B, 7, 2017
8JVE
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BU of 8jve by Molmil
Identification and characterization of inhibitors covalently modifying catalytic cysteine of UBE2T and blocking ubiquitin transfer
分子名称: 1,2-ETHANEDIOL, 1-(3-methoxyphenyl)-1,2,3,4-tetrazole, Ubiquitin-conjugating enzyme E2 T
著者Anantharajan, J, Baburajendran, N.
登録日2023-06-28
公開日2023-11-29
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Identification and characterization of inhibitors covalently modifying catalytic cysteine of UBE2T and blocking ubiquitin transfer.
Biochem.Biophys.Res.Commun., 689, 2023
5D1K
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BU of 5d1k by Molmil
Crystal Structure of UbcH5B in Complex with the RING-U5BR Fragment of AO7
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, E3 ubiquitin-protein ligase RNF25, ...
著者Liang, Y.-H, Li, S, Weissman, A.M, Ji, X.
登録日2015-08-04
公開日2015-10-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Insights into Ubiquitination from the Unique Clamp-like Binding of the RING E3 AO7 to the E2 UbcH5B.
J.Biol.Chem., 290, 2015
6GUM
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BU of 6gum by Molmil
Structure of the A.thaliana E1 UFD domain in complex with E2
分子名称: GLYCEROL, SAE2, SUMO-conjugating enzyme SCE1
著者Liu, B, Lois, L.M, Reverter, D.
登録日2018-06-19
公開日2019-07-03
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.792 Å)
主引用文献Structural insights into SUMO E1-E2 interactions in Arabidopsis uncovers a distinctive platform for securing SUMO conjugation specificity across evolution.
Biochem.J., 476, 2019
7BOL
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BU of 7bol by Molmil
ubiquitin-conjugating enzyme, Ube2D2
分子名称: Ubiquitin-conjugating enzyme E2 D2
著者Lee, S.O, Ryu, K.S, Chi, S.-W.
登録日2020-03-19
公開日2021-03-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.797 Å)
主引用文献MUL1-RING recruits the substrate, p53-TAD as a complex with UBE2D2-UB conjugate.
Febs J., 2022
2GRN
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BU of 2grn by Molmil
Crystal Structure of human RanGAP1-Ubc9
分子名称: Ran GTPase-activating protein 1, Ubiquitin-conjugating enzyme E2 I
著者Yunus, A.A, Lima, C.D.
登録日2006-04-24
公開日2006-05-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Lysine activation and functional analysis of E2-mediated conjugation in the SUMO pathway.
Nat.Struct.Mol.Biol., 13, 2006
2BEP
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BU of 2bep by Molmil
Crystal structure of ubiquitin conjugating enzyme E2-25K
分子名称: BETA-MERCAPTOETHANOL, UBIQUITIN-CONJUGATING ENZYME E2-25 KDA
著者Pichler, A, Knipscheer, P, Oberhofer, E, Van Dijk, W.J, Korner, R, Velgaard Olsen, J, Jentsch, S, Melchior, F, Sixma, T.K.
登録日2004-11-29
公開日2005-02-16
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Sumo Imodification of the Ubiquitin Conjugating Enzyme E2-25K
Nat.Struct.Mol.Biol., 12, 2005
6W7Z
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BU of 6w7z by Molmil
RNF12 RING domain in complex with Ube2d2
分子名称: E3 ubiquitin-protein ligase RLIM, GLYCEROL, Ubiquitin-conjugating enzyme E2 D2, ...
著者Middleton, A.J, Day, C.L.
登録日2020-03-19
公開日2020-05-20
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The RING Domain of RING Finger 12 Efficiently Builds Degradative Ubiquitin Chains.
J.Mol.Biol., 432, 2020
5ULF
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BU of 5ulf by Molmil
Crystal Structure of a UbcH5b~Ub conjugate
分子名称: GLYCEROL, Ubiquitin, Ubiquitin-conjugating enzyme E2 D2
著者Middleton, A.J, Day, C.L, Wright, J.D.
登録日2017-01-24
公開日2017-06-07
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Discovery of new non-covalent ubiquitin binding sites on UbcH5
To be published
1ZUO
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BU of 1zuo by Molmil
Structure of Human Ubiquitin-Conjugating Enzyme (UBCi) Involved in Embryo Attachment and Implantation
分子名称: BETA-MERCAPTOETHANOL, Hypothetical protein LOC92912
著者Walker, J.R, Avvakumov, G.V, Cui, H, Newman, E.M, Mackenzie, F, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2005-05-31
公開日2005-07-05
最終更新日2012-11-28
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
Mol Cell Proteomics, 11, 2012
4DHI
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BU of 4dhi by Molmil
Structure of C. elegans OTUB1 bound to human UBC13
分子名称: Ubiquitin thioesterase otubain-like, Ubiquitin-conjugating enzyme E2 N
著者Wiener, R, Zhang, X, Wang, T, Wolberger, C.
登録日2012-01-27
公開日2012-02-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The mechanism of OTUB1-mediated inhibition of ubiquitination.
Nature, 483, 2012
3H8K
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BU of 3h8k by Molmil
Crystal structure of Ube2g2 complxed with the G2BR domain of gp78 at 1.8-A resolution
分子名称: Autocrine motility factor receptor, isoform 2, Ubiquitin-conjugating enzyme E2 G2
著者Kalathur, R.C, Das, R, Li, J, Byrd, R.A, Ji, X.
登録日2009-04-29
公開日2009-07-14
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Allosteric activation of E2-RING finger-mediated ubiquitylation by a structurally defined specific E2-binding region of gp78.
Mol.Cell, 34, 2009
3K9O
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BU of 3k9o by Molmil
The crystal structure of E2-25K and UBB+1 complex
分子名称: Ubiquitin, Ubiquitin-conjugating enzyme E2 K
著者Kang, G.B, Ko, S, Song, S.M, Lee, W, Eom, S.H.
登録日2009-10-16
公開日2010-09-08
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Basis of E2-25K/UBB+1 Interaction for Neurotoxicity of Alzheimer Disease by Proteasome Inhibition
To be Published
3TGD
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BU of 3tgd by Molmil
Crystal structure of the human ubiquitin-conjugating enzyme (E2) UbcH5b
分子名称: Ubiquitin-conjugating enzyme E2 D2
著者Page, R.C, Amick, J, Misra, S.
登録日2011-08-17
公開日2011-08-31
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of the human ubiquitin-conjugating enzyme (E2) UbcH5b
To be Published
4NR3
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BU of 4nr3 by Molmil
Crystal Structure of a human Mms2/Ubc13 L121G mutant
分子名称: Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2
著者Hodge, C.D, Edwards, R.A, Glover, J.N.M.
登録日2013-11-26
公開日2014-12-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.802 Å)
主引用文献Stochastic gate dynamics regulate the catalytic activity of ubiquitination enzymes.
J.Am.Chem.Soc., 136, 2014
4YII
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BU of 4yii by Molmil
Structure of an APC2-UBCH10 complex reveals distinctive cullin-RING ligase mechanism for Anaphase-promoting complex/Cyclosome
分子名称: Anaphase-promoting complex subunit 2, Ubiquitin-conjugating enzyme E2 C
著者Brown, N.G, Cho, S.E, Schulman, B.A.
登録日2015-03-02
公開日2015-04-08
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.804 Å)
主引用文献Crystal Structure of E2 Complex
Proc.Natl.Acad.Sci.USA, 2015
4JQU
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BU of 4jqu by Molmil
Crystal structure of Ubc7p in complex with the U7BR of Cue1p
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Coupling of ubiquitin conjugation to ER degradation protein 1, DI(HYDROXYETHYL)ETHER, ...
著者Liang, Y.-H, Metzger, M.B, Weissman, A.M, Ji, X.
登録日2013-03-20
公開日2013-05-29
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献A Structurally Unique E2-Binding Domain Activates Ubiquitination by the ERAD E2, Ubc7p, through Multiple Mechanisms.
Mol.Cell, 50, 2013
7AHZ
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BU of 7ahz by Molmil
Crystal structure of Western clawed frog MDM2 RING domain homodimer bound to UbcH5B-Ub
分子名称: CHLORIDE ION, E3 ubiquitin-protein ligase Mdm2, Polyubiquitin-B, ...
著者Magnussen, H.M, Huang, D.T.
登録日2020-09-25
公開日2021-01-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Identification of a Catalytic Active but Non-Aggregating MDM2 RING Domain Variant.
J.Mol.Biol., 433, 2021
2A7L
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BU of 2a7l by Molmil
Structure of the human hypothetical ubiquitin-conjugating enzyme, LOC55284
分子名称: Hypothetical ubiquitin-conjugating enzyme LOC55284, SODIUM ION
著者Walker, J.R, Avvakumov, G.V, Xue, S, Newman, E.M, Mackenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2005-07-05
公開日2005-09-06
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
Mol Cell Proteomics, 11, 2012
6SQS
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BU of 6sqs by Molmil
Crystal structure of cat phospho-Ser429 MDM2 RING domain bound to UbcH5B-Ub
分子名称: E3 ubiquitin-protein ligase Mdm2, Ubiquitin-40S ribosomal protein S27a, Ubiquitin-conjugating enzyme E2 D2, ...
著者Magnussen, H.M, Ahmed, S.F, Huang, D.T.
登録日2019-09-04
公開日2020-05-06
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain.
Nat Commun, 11, 2020
2R0J
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BU of 2r0j by Molmil
Crystal structure of the putative ubiquitin conjugating enzyme, PFE1350c, from Plasmodium falciparum
分子名称: Ubiquitin carrier protein
著者Wernimont, A.K, Lew, J, Lin, Y.H, Hassanali, A, Kozieradzki, I, Zhao, Y, Schapira, M, Bochkarev, A, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Hui, R, Brokx, S, Structural Genomics Consortium (SGC)
登録日2007-08-20
公開日2007-09-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of the putative ubiquitin conjugating enzyme, PFE1350c, from Plasmodium falciparum.
To be Published
1X23
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BU of 1x23 by Molmil
Crystal structure of ubch5c
分子名称: Ubiquitin-conjugating enzyme E2 D3
著者Nakanishi, M, Teshima, N, Mizushima, T, Murata, S, Tanaka, K, Yamane, T.
登録日2005-04-19
公開日2005-05-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of ubch5c
To be Published
1J7D
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BU of 1j7d by Molmil
Crystal Structure of hMms2-hUbc13
分子名称: MMS2, UBIQUITIN-CONJUGATING ENZYME E2-17 KDA
著者Moraes, T.F, Edwards, R.A, McKenna, S, Pashushok, L, Xiao, W, Glover, J.N.M, Ellison, M.J.
登録日2001-05-16
公開日2001-08-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2-hUbc13.
Nat.Struct.Biol., 8, 2001
6MJ9
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BU of 6mj9 by Molmil
CRYSTAL STRUCTURE OF UBIQUITIN-CONJUGATING ENZYME FROM NAEGLERIA FOWLERI, APO FORM
分子名称: Ubiquitin-conjugating enzyme
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2018-09-20
公開日2018-10-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献CRYSTAL STRUCTURE OF UBIQUITIN-CONJUGATING ENZYME FROM NAEGLERIA FOWLERI, APO FORM
To Be Published

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