PDB: 197 件ウェブページステータス検索Chemie searchBIRD

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4WWY	human cationic trypsin G193R mutant in complex with bovine pancreatic trypsin inhibitor 分子名称: CALCIUM ION, Pancreatic trypsin inhibitor, SULFATE ION, ... 著者 Alloy, A, Kayode, O, Soares, A.S, Wang, R, Radisky, E.S. 登録日 2014-11-12 公開日 2015-07-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Mesotrypsin Has Evolved Four Unique Residues to Cleave Trypsin Inhibitors as Substrates. J.Biol.Chem., 290, 2015
4U32	Human mesotrypsin complexed with HAI-2 Kunitz domain 1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Kunitz-type protease inhibitor 2, ... 著者 Wang, R, Soares, A.S, Radisky, E.S. 登録日 2014-07-18 公開日 2014-10-15 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Sequence and Conformational Specificity in Substrate Recognition: SEVERAL HUMAN KUNITZ PROTEASE INHIBITOR DOMAINS ARE SPECIFIC SUBSTRATES OF MESOTRYPSIN. J.Biol.Chem., 289, 2014
4U30	Human mesotrypsin complexed with bikunin Kunitz domain 2 分子名称: CALCIUM ION, Trypsin-3, Trypstatin 著者 Wang, R, Soares, A.S, Radisky, E.S. 登録日 2014-07-18 公開日 2014-10-15 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Sequence and Conformational Specificity in Substrate Recognition: SEVERAL HUMAN KUNITZ PROTEASE INHIBITOR DOMAINS ARE SPECIFIC SUBSTRATES OF MESOTRYPSIN. J.Biol.Chem., 289, 2014
4TPI	THE REFINED 2.2-ANGSTROMS (0.22-NM) X-RAY CRYSTAL STRUCTURE OF THE TERNARY COMPLEX FORMED BY BOVINE TRYPSINOGEN, VALINE-VALINE AND THE ARG15 ANALOGUE OF BOVINE PANCREATIC TRYPSIN INHIBITOR 分子名称: BOVINE PANCREATIC TRYPSIN INHIBITOR, CALCIUM ION, SULFATE ION, ... 著者 Bode, W, Walter, J. 登録日 1985-06-11 公開日 1985-11-08 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The refined 2.2-A (0.22-nm) X-ray crystal structure of the ternary complex formed by bovine trypsinogen, valine-valine and the Arg15 analogue of bovine pancreatic trypsin inhibitor Eur.J.Biochem., 144, 1984
4PTI	THE GEOMETRY OF THE REACTIVE SITE AND OF THE PEPTIDE GROUPS IN TRYPSIN, TRYPSINOGEN AND ITS COMPLEXES WITH INHIBITORS 分子名称: TRYPSIN INHIBITOR 著者 Huber, R, Kukla, D, Ruehlmann, A, Epp, O, Formanek, H, Deisenhofer, J, Steigemann, W. 登録日 1982-09-27 公開日 1983-01-18 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 The Geometry of the Reactive Site and of the Peptide Groups in Trypsin, Trypsinogen and its Complexes with Inhibitors Acta Crystallogr.,Sect.B, 39, 1983
4NTY	Cesium sites in the crystal structure of acid-sensing ion channel in complex with snake toxin 分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Acid-sensing ion channel 1, Basic phospholipase A2 homolog Tx-beta, ... 著者 Baconguis, I, Bohlen, C.J, Goehring, A, Julius, D, Gouaux, E. 登録日 2013-12-02 公開日 2014-02-19 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 X-ray structure of Acid-sensing ion channel 1-snake toxin complex reveals open state of a na(+)-selective channel. Cell(Cambridge,Mass.), 156, 2014
4NTX	Structure of acid-sensing ion channel in complex with snake toxin and amiloride 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3,5-DIAMINO-N-(AMINOIMINOMETHYL)-6-CHLOROPYRAZINECARBOXAMIDE, Acid-sensing ion channel 1, ... 著者 Baconguis, I, Bohlen, C.J, Goehring, A, Julius, D, Gouaux, E. 登録日 2013-12-02 公開日 2014-02-19 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 X-ray structure of Acid-sensing ion channel 1-snake toxin complex reveals open state of a na(+)-selective channel. Cell(Cambridge,Mass.), 156, 2014
4NTW	Structure of acid-sensing ion channel in complex with snake toxin 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel 1, Basic phospholipase A2 homolog Tx-beta, ... 著者 Baconguis, I, Bohlen, C.J, Goehring, A, Julius, D, Gouaux, E. 登録日 2013-12-02 公開日 2014-02-19 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 X-ray structure of Acid-sensing ion channel 1-snake toxin complex reveals open state of a na(+)-selective channel. Cell(Cambridge,Mass.), 156, 2014
4ISO	Crystal Structure of Matriptase in complex with its inhibitor HAI-1 分子名称: DI(HYDROXYETHYL)ETHER, GLUTATHIONE, GLYCEROL, ... 著者 Huang, M.D, Zhao, B.Y, Yuan, C, Li, R. 登録日 2013-01-16 公開日 2013-03-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Crystal structures of matriptase in complex with its inhibitor hepatocyte growth factor activator inhibitor-1. J.Biol.Chem., 288, 2013
4ISN	Crystal Structure of Matriptase in complex with its inhibitor HAI-1 分子名称: GLUTATHIONE, Kunitz-type protease inhibitor 1, Suppressor of tumorigenicity 14 protein, ... 著者 Huang, M.D, Zhao, B.Y, Yuan, C, Li, R. 登録日 2013-01-16 公開日 2013-03-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Crystal structures of matriptase in complex with its inhibitor hepatocyte growth factor activator inhibitor-1. J.Biol.Chem., 288, 2013
4ISL	Crystal Structure of the inactive Matriptase in complex with its inhibitor HAI-1 分子名称: GLUTATHIONE, GLYCEROL, Kunitz-type protease inhibitor 1, ... 著者 Huang, M.D, Zhao, B.Y, Yuan, C, Li, R. 登録日 2013-01-16 公開日 2013-03-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Crystal structures of matriptase in complex with its inhibitor hepatocyte growth factor activator inhibitor-1. J.Biol.Chem., 288, 2013
4DTG	Hemostatic effect of a monoclonal antibody mAb 2021 blocking the interaction between FXa and TFPI in a rabbit hemophilia model 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, Humanized recombinant FAB fragment, ... 著者 Svensson, L.A, Breinholt, J, Krogh, B.O, Hilden, I. 登録日 2012-02-21 公開日 2012-06-13 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Hemostatic effect of a monoclonal antibody mAb 2021 blocking the interaction between FXa and TFPI in a rabbit hemophilia model. Blood, 119, 2012
4DG4	Human mesotrypsin-S39Y complexed with bovine pancreatic trypsin inhibitor (BPTI) 分子名称: CALCIUM ION, PRSS3 protein, Pancreatic trypsin inhibitor, ... 著者 Salameh, M.A, Soares, A.S, Radisky, E.S. 登録日 2012-01-24 公開日 2012-09-12 最終更新日 2018-01-24 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Presence versus absence of hydrogen bond donor Tyr-39 influences interactions of cationic trypsin and mesotrypsin with protein protease inhibitors. Protein Sci., 21, 2012
4BQD	KD1 of human TFPI in complex with a synthetic peptide 分子名称: GLYCEROL, PEPTIDE, TISSUE FACTOR PATHWAY INHIBITOR (LIPOPROTEIN-ASSOCIATED COAGULATION INHIBITOR) VARIANT 著者 Griessner, A, Brandstetter, H. 登録日 2013-05-30 公開日 2013-12-04 最終更新日 2019-07-17 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 Small Peptides Blocking Inhibition of Factor Xa and Tissue Factor-Factor Viia by Tissue Factor Pathway Inhibitor (Tfpi) J.Biol.Chem., 289, 2014
4BNR	Extremely stable complex of crayfish trypsin with bovine trypsin inhibitor 分子名称: CALCIUM ION, HEPATOPANCREAS TRYPSIN, PANCREATIC TRYPSIN INHIBITOR, ... 著者 Molnar, T, Voros, J, Szeder, B, Takats, K, Kardos, J, Katona, G, Graf, L. 登録日 2013-05-17 公開日 2013-09-04 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Comparison of Complexes Formed by a Crustacean and a Vertebrate Trypsin with Bovine Pancreatic Trypsin Inhibitor - the Key to Achieving Extreme Stability? FEBS J., 280, 2013
4BD9	Structure of the complex between SmCI and human carboxypeptidase A4 分子名称: CARBOXYPEPTIDASE A4, CARBOXYPEPTIDASE INHIBITOR SMCI, ZINC ION 著者 Alonso-del-Ribero, M, Reytor, M.L, Trejo, S.A, Chavez, M.A, Aviles, F.X, Reverter, D. 登録日 2012-10-05 公開日 2013-07-17 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 A Noncanonical Mechanism of Carboxypeptidase Inhibition Revealed by the Crystal Structure of the Tri-Kunitz Smci in Complex with Human Cpa4. Structure, 21, 2013
3WNY	A simplified BPTI variant with poly Lys amino acid tag (C3K) at the C-terminus 分子名称: Bovine Pancreatic Trypsin Inhibitor, SULFATE ION 著者 Islam, M.M. 登録日 2013-12-18 公開日 2014-06-18 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 A simplified BPTI variant with poly Lys amino acid tag (C3K) at the C-terminus to be published
3UOU	Crystal structure of the Kunitz-type protease inhibitor ShPI-1 Lys13Leu mutant in complex with pancreatic elastase 分子名称: Chymotrypsin-like elastase family member 1, GLYCEROL, Kunitz-type proteinase inhibitor SHPI-1, ... 著者 Garcia-Fernandez, R, Perbandt, M, Rehders, D, Gonzalez-Gonzalez, Y, Chavez, M.A, Betzel, C, Redecke, L. 登録日 2011-11-17 公開日 2012-11-21 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Three-dimensional Structure of a Kunitz-type Inhibitor in Complex with an Elastase-like Enzyme. J.Biol.Chem., 290, 2015
3UIR	Crystal structure of the plasmin-textilinin-1 complex 分子名称: Plasmin light chain B, SULFATE ION, Textilinin-1 著者 Guddat, L.W, Millers, E.K, de jersey, J, Lavin, M.F, Masci, P.M. 登録日 2011-11-05 公開日 2012-12-26 最終更新日 2013-07-17 実験手法 X-RAY DIFFRACTION (2.777 Å) 主引用文献 The structure of human microplasmin in complex with textilinin-1, an aprotinin-like inhibitor from the Australian brown snake. Plos One, 8, 2013
3U1J	Aprotinin bound to Dengue virus protease 分子名称: Pancreatic trypsin inhibitor, Serine protease NS3, Serine protease subunit NS2B 著者 Noble, C.G. 登録日 2011-09-30 公開日 2011-11-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Ligand-bound structures of the dengue virus protease reveal the active conformation J.Virol., 86, 2012
3TPI	THE GEOMETRY OF THE REACTIVE SITE AND OF THE PEPTIDE GROUPS IN TRYPSIN, TRYPSINOGEN AND ITS COMPLEXES WITH INHIBITORS 分子名称: BOVINE PANCREATIC TRYPSIN INHIBITOR, CALCIUM ION, ISOLEUCINE, ... 著者 Huber, R, Bode, W, Deisenhofer, J, Schwager, P. 登録日 1982-09-27 公開日 1983-01-18 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The Geometry of the Reactive Site and of the Peptide Groups in Trypsin, Trypsinogen and its Complexes with Inhibitors Acta Crystallogr.,Sect.B, 39, 1983
3TGK	TRYPSINOGEN MUTANT D194N AND DELETION OF ILE 16-VAL 17 COMPLEXED WITH BOVINE PANCREATIC TRYPSIN INHIBITOR (BPTI) 分子名称: CALCIUM ION, PANCREATIC TRYPSIN INHIBITOR, SULFATE ION, ... 著者 Pasternak, A, White, A, Jeffery, C.J, Medina, N, Cahoon, M, Ringe, D, Hedstrom, L. 登録日 1998-07-19 公開日 2001-07-04 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The energetic cost of induced fit catalysis: Crystal structures of trypsinogen mutants with enhanced activity and inhibitor affinity. Protein Sci., 10, 2001
3TGJ	S195A TRYPSINOGEN COMPLEXED WITH BOVINE PANCREATIC TRYPSIN INHIBITOR (BPTI) 分子名称: BOVINE PANCREATIC TRYPSIN INHIBITOR, CALCIUM ION, SULFATE ION, ... 著者 Pasternak, A, Ringe, D, Hedstrom, L. 登録日 1998-07-16 公開日 1998-12-23 最終更新日 2021-11-03 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Comparison of Anionic and Cationic Trypsinogens: The Anionic Activation Domain is More Flexible in Solution and Differs in its Mode of Bpti Binding in the Crystal Structure Protein Sci., 8, 1999
3TGI	WILD-TYPE RAT ANIONIC TRYPSIN COMPLEXED WITH BOVINE PANCREATIC TRYPSIN INHIBITOR (BPTI) 分子名称: BOVINE PANCREATIC TRYPSIN INHIBITOR, CALCIUM ION, SULFATE ION, ... 著者 Pasternak, A, Ringe, D, Hedstrom, L. 登録日 1998-07-15 公開日 1998-12-23 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Comparison of Anionic and Cationic Trypsinogens: The Anionic Activation Domain is More Flexible in Solution and Differs in its Mode of Bpti Binding in the Crystal Structure Protein Sci., 8, 1999
3T62	Crystal structure of recombinant Kunitz Type serine protease Inhibitor-1 from the Caribbean Sea anemone Stichodactyla helianthus in complex with bovine chymotrypsin 分子名称: Chymotrypsinogen A, Kunitz-type proteinase inhibitor SHPI-1, SULFATE ION 著者 Garcia-Fernandez, R, Dominguez, R, Oberthuer, D, Pons, T, Gonzalez-Gonzalez, Y, Chavez, M.A, Betzel, C, Redecke, L. 登録日 2011-07-28 公開日 2012-08-01 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural insights into chymotrypsin inhibition by the Kunitz-type inhibitor-1 from the marine invertebrate Stichodactyla helianthus To be Published

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