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4DG4

Human mesotrypsin-S39Y complexed with bovine pancreatic trypsin inhibitor (BPTI)

Summary for 4DG4
Entry DOI10.2210/pdb4dg4/pdb
Related2R9P
DescriptorPRSS3 protein, Pancreatic trypsin inhibitor, SULFATE ION, ... (5 entities in total)
Functional Keywordshuman mesotrypsin, canonical inhibitor, bpti, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHomo sapiens (human)
More
Cellular locationSecreted: P00974
Total number of polymer chains8
Total formula weight125790.07
Authors
Salameh, M.A.,Soares, A.S.,Radisky, E.S. (deposition date: 2012-01-24, release date: 2012-09-12, Last modification date: 2018-01-24)
Primary citationSalameh, M.A.,Soares, A.S.,Alloy, A.,Radisky, E.S.
Presence versus absence of hydrogen bond donor Tyr-39 influences interactions of cationic trypsin and mesotrypsin with protein protease inhibitors.
Protein Sci., 21:1103-1112, 2012
Cited by
PubMed: 22610453
DOI: 10.1002/pro.2097
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.4 Å)
Structure validation

217705

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