2R9P

Human mesotrypsin complexed with bovine pancreatic trypsin inhibitor(BPTI)

Summary for 2R9P

• Entry DOI: 10.2210/pdb2r9p/pdb
• Related: 2RA3
• Descriptor: Trypsin-3, Pancreatic trypsin inhibitor, SULFATE ION, ... (4 entities in total)
• Functional Keywords: human mesotrypsin, serine protease, bovine pancreatic trypsin inhibitor, bpti, alternative splicing, calcium, digestion, hydrolase, metal-binding, secreted, sulfation, zymogen, pharmaceutical, protease inhibitor, serine protease inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted: P35030 P00974
• Total number of polymer chains: 8
• Total formula weight: 125061.36

Authors

Salameh, M.A.,Soares, A.S.,Radisky, E.S. (deposition date: 2007-09-13, release date: 2007-12-11, Last modification date: 2023-08-30)

• Primary citation: Salameh, M.A.,Soares, A.S.,Hockla, A.,Radisky, E.S.; Structural Basis for Accelerated Cleavage of Bovine Pancreatic Trypsin Inhibitor (BPTI) by Human Mesotrypsin.; J.Biol.Chem., 283:4115-4123, 2008; PubMed: 18077447; DOI: 10.1074/jbc.M708268200

Experimental method

X-RAY DIFFRACTION (1.4 Å)