2R9P
Human mesotrypsin complexed with bovine pancreatic trypsin inhibitor(BPTI)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Trypsin-3 | polymer | 224 | 24257.5 | 4 | UniProt (P35030) Pfam (PF00089) | Homo sapiens (human) | Trypsin III, Brain trypsinogen, Mesotrypsinogen, Trypsin IV, Serine protease 3, Serine protease 4 |
| 2 | E, F, G, H (I, E, F, G) | Pancreatic trypsin inhibitor | polymer | 58 | 6527.6 | 4 | UniProt (P00974) Pfam (PF00014) | Bos taurus (cattle) | Basic protease inhibitor, BPI, BPTI, Aprotinin |
| 3 | AA, BA, I, J, K... (G, A, B, C, D...) | SULFATE ION | non-polymer | 96.1 | 20 | Chemie (SO4) | |||
| 4 | CA, DA, EA, FA, GA... (A, B, C, D, I...) | water | water | 18.0 | 633 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 16 - 246 (UniProt: P35030)
| PDB | External Database | Details |
|---|---|---|
| Ala 195 | Ser 257 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 123140.1 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 1921.3 | |
| All* | Total formula weight | 125061.4 |
