4WWY
human cationic trypsin G193R mutant in complex with bovine pancreatic trypsin inhibitor
Summary for 4WWY
| Entry DOI | 10.2210/pdb4wwy/pdb |
| Related | 4WXV |
| Descriptor | Trypsin-1, Pancreatic trypsin inhibitor, SULFATE ION, ... (5 entities in total) |
| Functional Keywords | trypsin inhibitors, complex, bpti, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 4 |
| Total formula weight | 62300.31 |
| Authors | Alloy, A.,Kayode, O.,Soares, A.S.,Wang, R.,Radisky, E.S. (deposition date: 2014-11-12, release date: 2015-07-22, Last modification date: 2023-09-27) |
| Primary citation | Alloy, A.P.,Kayode, O.,Wang, R.,Hockla, A.,Soares, A.S.,Radisky, E.S. Mesotrypsin Has Evolved Four Unique Residues to Cleave Trypsin Inhibitors as Substrates. J.Biol.Chem., 290:21523-21535, 2015 Cited by PubMed: 26175157DOI: 10.1074/jbc.M115.662429 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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