5XFQ
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5XFO
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5XFR
| Ternary complex of MTF2, DNA and histone | 分子名称: | DNA (5'-D(*GP*GP*GP*CP*GP*GP*CP*CP*GP*CP*CP*CP*T)-3'), Metal-response element-binding transcription factor 2, Peptide from Histone H3.1, ... | 著者 | Wang, Z, Li, H. | 登録日 | 2017-04-11 | 公開日 | 2017-09-13 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Polycomb-like proteins link the PRC2 complex to CpG islands Nature, 549, 2017
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5VGI
| Crystal Structure of KDM4 with the Small Molecule Inhibitor QC6352 | 分子名称: | 3-[({(1R)-6-[methyl(phenyl)amino]-1,2,3,4-tetrahydronaphthalen-1-yl}methyl)amino]pyridine-4-carboxylic acid, Lysine-specific demethylase 4A, NICKEL (II) ION, ... | 著者 | Hosfield, D.J. | 登録日 | 2017-04-11 | 公開日 | 2017-09-27 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Design of KDM4 Inhibitors with Antiproliferative Effects in Cancer Models. ACS Med Chem Lett, 8, 2017
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5VMP
| Crystal Structure of Human KDM4 with Small Molecule Inhibitor QC5714 | 分子名称: | 3-({[(1R)-6-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl]methyl}amino)pyridine-4-carboxylic acid, Lysine-specific demethylase 4A, NICKEL (II) ION, ... | 著者 | Hosfield, D.J. | 登録日 | 2017-04-28 | 公開日 | 2017-09-27 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | Design of KDM4 Inhibitors with Antiproliferative Effects in Cancer Models. ACS Med Chem Lett, 8, 2017
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6IIR
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6IIQ
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6IIS
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6IIT
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6IIP
| Apo-form structure of the HRP3 PWWP domain | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Hepatoma-derived growth factor-related protein 3, SULFATE ION | 著者 | Wang, Z, Tian, W. | 登録日 | 2018-10-07 | 公開日 | 2019-04-24 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (0.951 Å) | 主引用文献 | Apo-form structure of the HRP3 PWWP domain Nucleic Acids Res., 2019
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6J0D
| Crystal structure of OsSUF4 | 分子名称: | ZINC ION, transcription factor | 著者 | Wang, B, Luo, Q. | 登録日 | 2018-12-24 | 公開日 | 2019-11-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The transcription factor OsSUF4 interacts with SDG725 in promoting H3K36me3 establishment. Nat Commun, 10, 2019
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6S01
| Structure of LEDGF PWWP domain bound H3K36 methylated nucleosome | 分子名称: | Histone H2A, Histone H2B 1.1, Histone H3, ... | 著者 | Wang, H, Farnung, L, Dienemann, C, Cramer, P. | 登録日 | 2019-06-13 | 公開日 | 2019-12-18 | 最終更新日 | 2020-01-22 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structure of H3K36-methylated nucleosome-PWWP complex reveals multivalent cross-gyre binding. Nat.Struct.Mol.Biol., 27, 2020
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6WAT
| complex structure of PHF1 | 分子名称: | Histone H3.1t peptide, PHD finger protein 1, UNKNOWN ATOM OR ION | 著者 | Dong, C, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Min, J.R, Structural Genomics Consortium (SGC) | 登録日 | 2020-03-26 | 公開日 | 2020-08-26 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural basis for histone variant H3tK27me3 recognition by PHF1 and PHF19. Elife, 9, 2020
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6WAU
| Complex structure of PHF19 | 分子名称: | Histone H3.1t peptide, PHD finger protein 19, UNKNOWN ATOM OR ION | 著者 | Dong, C, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Min, J.R, Structural Genomics Consortium (SGC) | 登録日 | 2020-03-26 | 公開日 | 2020-08-26 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural basis for histone variant H3tK27me3 recognition by PHF1 and PHF19. Elife, 9, 2020
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6WAV
| Crystal structure of PHF1 in complex with H3K36me3 substitution | 分子名称: | Histone H3.1, PHD finger protein 1, SULFATE ION, ... | 著者 | Dong, C, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Min, J.R, Structural Genomics Consortium (SGC) | 登録日 | 2020-03-26 | 公開日 | 2020-08-26 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural basis for histone variant H3tK27me3 recognition by PHF1 and PHF19. Elife, 9, 2020
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6WKR
| PRC2-AEBP2-JARID2 bound to H2AK119ub1 nucleosome | 分子名称: | DNA (314-MER), Histone H2A type 1, Histone H2B 1.1, ... | 著者 | Kasinath, V, Nogales, E, Beck, C, Sauer, P, Poepsel, S, Kosmatka, J, Faini, M, Toso, D, Aebersold, R. | 登録日 | 2020-04-16 | 公開日 | 2021-02-03 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | JARID2 and AEBP2 regulate PRC2 in the presence of H2AK119ub1 and other histone modifications. Science, 371, 2021
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6ZV0
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6ZV4
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6ZV3
| TFIIS N-terminal domain (TND) from human MED26 | 分子名称: | Mediator of RNA polymerase II transcription subunit 26 | 著者 | Veverka, V. | 登録日 | 2020-07-23 | 公開日 | 2021-12-01 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | A ubiquitous disordered protein interaction module orchestrates transcription elongation. Science, 374, 2021
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6ZV1
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6ZUY
| Human TFIIS N-terminal domain (TND) | 分子名称: | Transcription elongation factor A protein 1 | 著者 | Veverka, V. | 登録日 | 2020-07-23 | 公開日 | 2021-12-01 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | A ubiquitous disordered protein interaction module orchestrates transcription elongation. Science, 374, 2021
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6ZUZ
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6ZV2
| TFIIS N-terminal domain (TND) from human PPP1R10 | 分子名称: | Serine/threonine-protein phosphatase 1 regulatory subunit 10 | 著者 | Veverka, V. | 登録日 | 2020-07-23 | 公開日 | 2021-12-01 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | A ubiquitous disordered protein interaction module orchestrates transcription elongation. Science, 374, 2021
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7AT8
| Histone H3 recognition by nucleosome-bound PRC2 subunit EZH2. | 分子名称: | Histone H2A, Histone H2B 1.1, Histone H3.2, ... | 著者 | Finogenova, K, Benda, C, Schaefer, I.B, Poepsel, S, Strauss, M, Mueller, J. | 登録日 | 2020-10-29 | 公開日 | 2020-12-09 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Structural basis for PRC2 decoding of active histone methylation marks H3K36me2/3. Elife, 9, 2020
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7LH9
| Crystal structure of BRPF2 PWWP domain in complex with DNA | 分子名称: | Bromodomain-containing protein 1, DNA | 著者 | Zhang, M, Lei, M, Qin, S, Dong, A, Yang, A, Li, Y, Loppnau, P, Hughes, T.R, Arrowsmith, C.H, Edwards, A.M, Min, J, Liu, J, Structural Genomics Consortium (SGC) | 登録日 | 2021-01-21 | 公開日 | 2021-02-17 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structure of the BRPF2 PWWP domain in complex with DNA reveals a different binding mode than the HDGF family of PWWP domains. Biochim Biophys Acta Gene Regul Mech, 1864, 2021
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