7LH9

Crystal structure of BRPF2 PWWP domain in complex with DNA

Summary for 7LH9

• Entry DOI: 10.2210/pdb7lh9/pdb
• Descriptor: Bromodomain-containing protein 1, DNA (2 entities in total)
• Functional Keywords: brpf2, pwwp, structural genomics, structural genomics consortium, sgc, dna binding protein, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 12
• Total formula weight: 86542.48

Authors

Zhang, M.,Lei, M.,Qin, S.,Dong, A.,Yang, A.,Li, Y.,Loppnau, P.,Hughes, T.R.,Arrowsmith, C.H.,Edwards, A.M.,Min, J.,Liu, J.,Structural Genomics Consortium (SGC) (deposition date: 2021-01-21, release date: 2021-02-17, Last modification date: 2023-10-18)

• Primary citation: Zhang, M.,Lei, M.,Qin, S.,Dong, A.,Yang, A.,Li, Y.,Loppnau, P.,Hughes, T.R.,Min, J.,Liu, Y.; Crystal structure of the BRPF2 PWWP domain in complex with DNA reveals a different binding mode than the HDGF family of PWWP domains.; Biochim Biophys Acta Gene Regul Mech, 1864:194688-194688, 2021; PubMed: 33556623; DOI: 10.1016/j.bbagrm.2021.194688

Experimental method

X-RAY DIFFRACTION (2.6 Å)