3F23
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![BU of 3f23 by Molmil](/molmil-images/mine/3f23) | Crystal structure of Zalpha in complex with d(CGGCCG) | 分子名称: | DNA (5'-D(*DTP*DCP*DGP*DGP*DCP*DCP*DG)-3'), Double-stranded RNA-specific adenosine deaminase | 著者 | Ha, S.C, Choi, J, Kim, K.K. | 登録日 | 2008-10-28 | 公開日 | 2008-12-30 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | The structures of non-CG-repeat Z-DNAs co-crystallized with the Z-DNA-binding domain, hZ{alpha}ADAR1 Nucleic Acids Res., 37, 2009
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3FAU
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![BU of 3fau by Molmil](/molmil-images/mine/3fau) | Crystal Structure of human small-MutS related domain | 分子名称: | NEDD4-binding protein 2 | 著者 | Kim, T.G, Kwon, T.H, Ryu, E.K, Min, K, Heo, S.-D, Song, K.M, Jun, W.J, Jung, E. | 登録日 | 2008-11-18 | 公開日 | 2009-12-15 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Strcutral Dynamincs of the Endonuclease Small-MutS Related Domains of BCL3 binding protein To be Published
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3FB2
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![BU of 3fb2 by Molmil](/molmil-images/mine/3fb2) | Crystal structure of the human brain alpha spectrin repeats 15 and 16. Northeast Structural Genomics Consortium target HR5563a. | 分子名称: | Spectrin alpha chain, brain spectrin | 著者 | Vorobiev, S.M, Su, M, Seetharaman, J, Shastry, R, Foote, E.L, Ciccosanti, C, Janjua, H, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2008-11-18 | 公開日 | 2008-11-25 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of the human brain alpha spectrin repeats 15 and 16. To be Published
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3FJB
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3FCB
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![BU of 3fcb by Molmil](/molmil-images/mine/3fcb) | |
3FJI
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3FCO
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![BU of 3fco by Molmil](/molmil-images/mine/3fco) | Crystal Structure of 11beta-Hydroxysteroid Dehydrogenase 1 (11b-HSD1) in Complex with Benzamide Inhibitor | 分子名称: | Corticosteroid 11-beta-dehydrogenase isozyme 1, N-cyclopropyl-N-(cis-4-cyclopropyl-4-hydroxycyclohexyl)-4-[(1S)-2,2,2-trifluoro-1-hydroxy-1-methylethyl]benzamide, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Wang, Z, Sudom, A, Walker, N.P. | 登録日 | 2008-11-21 | 公開日 | 2009-12-01 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Optimization of novel di-substituted cyclohexylbenzamide derivatives as potent 11 beta-HSD1 inhibitors. Bioorg.Med.Chem.Lett., 19, 2009
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3FKI
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![BU of 3fki by Molmil](/molmil-images/mine/3fki) | 12-Subunit RNA Polymerase II Refined with Zn-SAD data | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | 著者 | Meyer, P.A, Ye, P, Suh, M.H, Zhang, M, Fu, J. | 登録日 | 2008-12-16 | 公開日 | 2009-03-10 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.88 Å) | 主引用文献 | Structure of the 12-Subunit RNA Polymerase II Refined with the Aid of Anomalous Diffraction Data J.Biol.Chem., 284, 2009
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3FFN
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3F9C
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3F5U
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![BU of 3f5u by Molmil](/molmil-images/mine/3f5u) | Crystal structure of the death associated protein kinase in complex with AMPPNP and Mg2+ | 分子名称: | Death-associated protein kinase 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | McNamara, L.K, Watterson, D.M, Brunzelle, J.S. | 登録日 | 2008-11-04 | 公開日 | 2009-03-24 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural insight into nucleotide recognition by human death-associated protein kinase. Acta Crystallogr.,Sect.D, 65, 2009
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3FI4
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![BU of 3fi4 by Molmil](/molmil-images/mine/3fi4) | P38 kinase crystal structure in complex with RO4499 | 分子名称: | (2S)-1-{[3-(2-chlorophenyl)-6-(2,4-difluorophenoxy)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]amino}propan-2-ol, Mitogen-activated protein kinase 14 | 著者 | Kuglstatter, A, Knapp, M, Dunten, P. | 登録日 | 2008-12-10 | 公開日 | 2009-12-22 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Mapping Binding Pocket Volume: Potential Applications towards Ligand Design and Selectivity To be Published
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3FJ6
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3FC8
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![BU of 3fc8 by Molmil](/molmil-images/mine/3fc8) | |
3FQ4
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3FCX
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![BU of 3fcx by Molmil](/molmil-images/mine/3fcx) | Crystal structure of human esterase D | 分子名称: | CALCIUM ION, MAGNESIUM ION, S-formylglutathione hydrolase | 著者 | Wu, D, Li, Y, Song, G, Zhang, D, Shaw, N, Liu, Z.J. | 登録日 | 2008-11-24 | 公開日 | 2008-12-09 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystal structure of human esterase D: a potential genetic marker of retinoblastoma Faseb J., 23, 2009
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3F1N
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![BU of 3f1n by Molmil](/molmil-images/mine/3f1n) | Crystal structure of a high affinity heterodimer of HIF2 alpha and ARNT C-terminal PAS domains, with internally bound ethylene glycol. | 分子名称: | 1,2-ETHANEDIOL, Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1 | 著者 | Scheuermann, T.H, Tomchick, D.R, Machius, M, Guo, Y, Bruick, R.K, Gardner, K.H. | 登録日 | 2008-10-28 | 公開日 | 2009-01-20 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.479 Å) | 主引用文献 | Artificial ligand binding within the HIF2alpha PAS-B domain of the HIF2 transcription factor. Proc.Natl.Acad.Sci.USA, 106, 2009
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3F22
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![BU of 3f22 by Molmil](/molmil-images/mine/3f22) | Crystal structure of Zalpha in complex with d(CGTACG) | 分子名称: | DNA (5'-D(*DTP*DCP*DGP*DTP*DAP*DCP*DG)-3'), Double-stranded RNA-specific adenosine deaminase | 著者 | Ha, S.C, Choi, J, Kim, K.K. | 登録日 | 2008-10-28 | 公開日 | 2008-12-30 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The structures of non-CG-repeat Z-DNAs co-crystallized with the Z-DNA-binding domain, hZ{alpha}ADAR1 Nucleic Acids Res., 37, 2009
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3F2A
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![BU of 3f2a by Molmil](/molmil-images/mine/3f2a) | Crystal structure of human Pim-1 in complex with DAPPA | 分子名称: | (2E)-3-{3-[6-(4-methyl-1,4-diazepan-1-yl)pyrazin-2-yl]phenyl}prop-2-enoic acid, MAGNESIUM ION, Proto-oncogene serine/threonine-protein kinase Pim-1 | 著者 | Qian, K. | 登録日 | 2008-10-29 | 公開日 | 2009-03-10 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Hit to lead account of the discovery of a new class of inhibitors of Pim kinases and crystallographic studies revealing an unusual kinase binding mode. J.Med.Chem., 52, 2009
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3D1V
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3D5R
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![BU of 3d5r by Molmil](/molmil-images/mine/3d5r) | Crystal Structure of Efb-C (N138A) / C3d Complex | 分子名称: | Complement C3, Fibrinogen-binding protein | 著者 | Geisbrecht, B.V. | 登録日 | 2008-05-16 | 公開日 | 2008-09-09 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Electrostatic contributions drive the interaction between Staphylococcus aureus protein Efb-C and its complement target C3d. Protein Sci., 17, 2008
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3CFM
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3CJK
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![BU of 3cjk by Molmil](/molmil-images/mine/3cjk) | Crystal structure of the adduct HAH1-Cd(II)-MNK1. | 分子名称: | CADMIUM ION, Copper transport protein ATOX1, Copper-transporting ATPase 1 | 著者 | Banci, L, Bertini, I, Calderone, V, Felli, I, Della-Malva, N, Pavelkova, A, Rosato, A. | 登録日 | 2008-03-13 | 公開日 | 2008-12-30 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Copper(I)-mediated protein-protein interactions result from suboptimal interaction surfaces. Biochem.J., 422, 2009
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3CNK
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![BU of 3cnk by Molmil](/molmil-images/mine/3cnk) | Crystal Structure of the dimerization domain of human filamin A | 分子名称: | Filamin-A, SULFATE ION | 著者 | Lee, B.J, Seo, M.D, Seok, S.H, Lee, S.J, Kwon, A.R, Im, H. | 登録日 | 2008-03-26 | 公開日 | 2009-02-10 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Crystal structure of the dimerization domain of human filamin A Proteins, 75, 2008
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3CP9
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![BU of 3cp9 by Molmil](/molmil-images/mine/3cp9) | Crystal structure of the VEGFR2 kinase domain in complex with a pyridone inhibitor | 分子名称: | 3-(2-aminoquinazolin-6-yl)-1-(3,3-dimethylindolin-6-yl)-4-methylpyridin-2(1H)-one, Vascular endothelial growth factor receptor 2 | 著者 | Whittington, D.A, Long, A.M, Rose, P, Gu, Y, Zhao, H. | 登録日 | 2008-03-31 | 公開日 | 2008-06-17 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Discovery of Aryl Aminoquinazoline Pyridones as Potent, Selective, and Orally Efficacious Inhibitors of Receptor Tyrosine Kinase c-Kit. J.Med.Chem., 51, 2008
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