4WI5
 
 | | Structural mapping of the human IgG1 binding site for FcRn: hu3S193 Fc mutation H310A | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region | | 著者 | Farrugia, W, Burvenich, I.J.G, Scott, A.M, Ramsland, P.A. | | 登録日 | 2014-09-25 | | 公開日 | 2015-09-30 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural and functional mapping of human IgG1 binding site for FcRn in vivo using human FcRn transgenic mice
To Be Published
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4WI3
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4WI6
 | | Structural mapping of the human IgG1 binding site for FcRn: hu3S193 Fc mutation N434A | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region | | 著者 | Farrugia, W, Burvenich, I.J.G, Scott, A.M, Ramsland, P.A. | | 登録日 | 2014-09-25 | | 公開日 | 2015-09-30 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.201 Å) | | 主引用文献 | Structural and functional mapping of human IgG1 binding site for FcRn in vivo using human FcRn transgenic mice
To Be Published
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4X6L
 | | Crystal structure of S. aureus TarM in complex with UDP | | 分子名称: | TarM, URIDINE-5'-DIPHOSPHATE | | 著者 | Worrall, L.J, Sobhanifar, S, Gruninger, R.J, Strynadka, N.C. | | 登録日 | 2014-12-08 | | 公開日 | 2015-02-25 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.19 Å) | | 主引用文献 | Structure and mechanism of Staphylococcus aureus TarM, the wall teichoic acid alpha-glycosyltransferase.
Proc.Natl.Acad.Sci.USA, 112, 2015
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4V86
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4X7F
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4WI4
 | | Structural mapping of the human IgG1 binding site for FcRn: hu3S193 Fc mutation S254A | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region | | 著者 | Farrugia, W, Burvenich, I.J.G, Scott, A.M, Ramsland, P.A. | | 登録日 | 2014-09-25 | | 公開日 | 2015-09-30 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural and functional mapping of human IgG1 binding site for FcRn in vivo using human FcRn transgenic mice
To Be Published
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4WI9
 | | Structural mapping of the human IgG1 binding site for FcRn: hu3S193 Fc mutation I253A/H310A | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region, ... | | 著者 | Farrugia, W, Burvenich, I.J.G, Scott, A.M, Ramsland, P.A. | | 登録日 | 2014-09-25 | | 公開日 | 2015-09-30 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Structural and functional mapping of human IgG1 binding site for FcRn in vivo using human FcRn transgenic mice
To Be Published
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4X7P
 | | Crystal structure of apo S. aureus TarM | | 分子名称: | SULFATE ION, TarM | | 著者 | Worrall, L.J, Sobhanifar, S, Gruninger, R.J, Strynadka, N.C. | | 登録日 | 2014-12-09 | | 公開日 | 2015-02-18 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Structure and mechanism of Staphylococcus aureus TarM, the wall teichoic acid alpha-glycosyltransferase.
Proc.Natl.Acad.Sci.USA, 112, 2015
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8PK3
 | | CryoEM reconstruction of hemagglutinin HK68 of Influenza A virus bound to an Affimer reagent | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Affimer molecule (A31), ... | | 著者 | Debski-Antoniak, O, Flynn, A, Klebl, D.P, Tiede, C, Muench, S, Tomlinson, D, Fontana, J. | | 登録日 | 2023-06-24 | | 公開日 | 2024-01-03 | | 最終更新日 | 2024-08-28 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Exploiting the Affimer platform against influenza A virus.
Mbio, 15, 2024
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6PV8
 | | Human alpha3beta4 nicotinic acetylcholine receptor in complex with AT-1001 | | 分子名称: | (3-endo)-N-(2-bromophenyl)-9-methyl-9-azabicyclo[3.3.1]nonan-3-amine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Gharpure, A, Teng, J, Zhuang, Y, Noviello, C.M, Walsh, R.M, Cabuco, R, Howard, R.J, Zaveri, N.T, Lindahl, E, Hibbs, R.E. | | 登録日 | 2019-07-19 | | 公開日 | 2019-09-11 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.87 Å) | | 主引用文献 | Agonist Selectivity and Ion Permeation in the alpha 3 beta 4 Ganglionic Nicotinic Receptor.
Neuron, 104, 2019
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6PV7
 | | Human alpha3beta4 nicotinic acetylcholine receptor in complex with nicotine | | 分子名称: | (S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Gharpure, A, Teng, J, Zhuang, Y, Noviello, C.M, Walsh, R.M, Cabuco, R, Howard, R.J, Zaveri, N.T, Lindahl, E, Hibbs, R.E. | | 登録日 | 2019-07-19 | | 公開日 | 2019-09-11 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.34 Å) | | 主引用文献 | Agonist Selectivity and Ion Permeation in the alpha 3 beta 4 Ganglionic Nicotinic Receptor.
Neuron, 104, 2019
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4IML
 | | CrossFab binding to human Angiopoietin 2 | | 分子名称: | Crossed heavy chain (VH-Ckappa), Crossed light chain (VL-CH1), GLYCEROL | | 著者 | Fenn, S, Schiller, C, Griese, J, Hopfner, K.-P, Kettenberger, H. | | 登録日 | 2013-01-03 | | 公開日 | 2013-04-17 | | 最終更新日 | 2013-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.931 Å) | | 主引用文献 | Crystal Structure of an Anti-Ang2 CrossFab Demonstrates Complete Structural and Functional Integrity of the Variable Domain.
Plos One, 8, 2013
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2JRV
 | | The third dimensional structure of mab198-bound pep.1 for autoimmune myasthenia gravis | | 分子名称: | PEPTIDE PEP.1 | | 著者 | Jung, H.H, Yi, H.J, Lee, S.K, Lee, J.Y, Jung, H.J, Yang, S.T, Eu, Y.-J, Im, S.-H, Kim, J.I. | | 登録日 | 2007-06-29 | | 公開日 | 2008-07-01 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural analysis of immunotherapeutic peptides for autoimmune Myasthenia gravis
Biochemistry, 46, 2007
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2JRW
 | | Solution structure of Cyclic extended Pep1(Cyc.ext.Pep.1) for autoimmune myasthenia gravis | | 分子名称: | Cyclic extended Pep.1 | | 著者 | Jung, H.H, Yi, H.J, Lee, S.K, Lee, J.Y, Jung, H.J, Yang, S.T, Eu, Y.-J, Im, S.-H, Kim, J.I. | | 登録日 | 2007-06-29 | | 公開日 | 2008-07-01 | | 最終更新日 | 2022-03-09 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural analysis of immunotherapeutic peptides for autoimmune Myasthenia gravis
Biochemistry, 46, 2007
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4IMK
 | | Uncrossed Fab binding to human Angiopoietin 2 | | 分子名称: | GLYCEROL, Heavy Chain, Light Chain, ... | | 著者 | Fenn, S, Schiller, C, Griese, J.J, Hopfner, K.-P, Kettenberger, H. | | 登録日 | 2013-01-03 | | 公開日 | 2013-04-17 | | 最終更新日 | 2013-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.202 Å) | | 主引用文献 | Crystal Structure of an Anti-Ang2 CrossFab Demonstrates Complete Structural and Functional Integrity of the Variable Domain.
Plos One, 8, 2013
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4OVE
 | | X-ray Crystal Structure of Mouse Netrin-1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Meier, M, Nikodemus, D, Reuten, R, Patel, T.R, Orriss, G, Okun, N, Koch, M, Stetefeld, J. | | 登録日 | 2014-02-21 | | 公開日 | 2015-02-25 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | | 主引用文献 | Structural Decoding of the Netrin-1/UNC5 Interaction and its Therapeutical Implications in Cancers.
Cancer Cell, 29, 2016
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1Q9B
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5J7C
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8DLN
 | | Cryo-EM structure of SARS-CoV-2 Beta (B.1.351) spike protein in complex with human ACE2 (focused refinement of RBD and ACE2) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Spike glycoprotein | | 著者 | Zhu, X, Mannar, D, Saville, J.W, Srivastava, S.S, Berezuk, A.M, Zhou, S, Tuttle, K.S, Subramaniam, S. | | 登録日 | 2022-07-08 | | 公開日 | 2022-08-31 | | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | | 主引用文献 | SARS-CoV-2 variants of concern: spike protein mutational analysis and epitope for broad neutralization.
Nat Commun, 13, 2022
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8DLK
 | | Cryo-EM structure of SARS-CoV-2 Alpha (B.1.1.7) spike protein in complex with human ACE2 (focused refinement of RBD and ACE2) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Spike glycoprotein | | 著者 | Zhu, X, Mannar, D, Saville, J.W, Srivastava, S.S, Berezuk, A.M, Zhou, S, Tuttle, K.S, Subramaniam, S. | | 登録日 | 2022-07-08 | | 公開日 | 2022-08-31 | | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | | 主引用文献 | SARS-CoV-2 variants of concern: spike protein mutational analysis and epitope for broad neutralization.
Nat Commun, 13, 2022
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8DLR
 | | Cryo-EM structure of SARS-CoV-2 Gamma (P.1) spike protein in complex with Fab 4-8 (focused refinement of NTD and 4-8) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 4-8 heavy chain, Fab 4-8 light chain, ... | | 著者 | Zhu, X, Mannar, D, Saville, J.W, Srivastava, S.S, Berezuk, A.M, Zhou, S, Tuttle, K.S, Subramaniam, S. | | 登録日 | 2022-07-08 | | 公開日 | 2022-08-31 | | 実験手法 | ELECTRON MICROSCOPY (2.51 Å) | | 主引用文献 | SARS-CoV-2 variants of concern: spike protein mutational analysis and epitope for broad neutralization.
Nat Commun, 13, 2022
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8DLS
 | | Cryo-EM structure of SARS-CoV-2 Gamma (P.1) spike protein in complex with Fab 4A8 (focused refinement of NTD and 4A8) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 4A8 heavy chain, ... | | 著者 | Zhu, X, Mannar, D, Saville, J.W, Srivastava, S.S, Berezuk, A.M, Zhou, S, Tuttle, K.S, Subramaniam, S. | | 登録日 | 2022-07-08 | | 公開日 | 2022-08-31 | | 実験手法 | ELECTRON MICROSCOPY (2.66 Å) | | 主引用文献 | SARS-CoV-2 variants of concern: spike protein mutational analysis and epitope for broad neutralization.
Nat Commun, 13, 2022
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8DLP
 | | Cryo-EM structure of SARS-CoV-2 Gamma (P.1) spike protein in complex with human ACE2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... | | 著者 | Zhu, X, Mannar, D, Saville, J.W, Srivastava, S.S, Berezuk, A.M, Zhou, S, Tuttle, K.S, Subramaniam, S. | | 登録日 | 2022-07-08 | | 公開日 | 2022-08-31 | | 実験手法 | ELECTRON MICROSCOPY (2.64 Å) | | 主引用文献 | SARS-CoV-2 variants of concern: spike protein mutational analysis and epitope for broad neutralization.
Nat Commun, 13, 2022
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8DLV
 | | Cryo-EM structure of SARS-CoV-2 Epsilon (B.1.429) spike protein in complex with human ACE2 (focused refinement of RBD and ACE2) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Spike glycoprotein | | 著者 | Zhu, X, Mannar, D, Saville, J.W, Srivastava, S.S, Berezuk, A.M, Zhou, S, Tuttle, K.S, Subramaniam, S. | | 登録日 | 2022-07-08 | | 公開日 | 2022-08-31 | | 実験手法 | ELECTRON MICROSCOPY (3.11 Å) | | 主引用文献 | SARS-CoV-2 variants of concern: spike protein mutational analysis and epitope for broad neutralization.
Nat Commun, 13, 2022
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