PDB: 45953 件ウェブページステータス検索Chemie searchBIRD

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1P3O	Crystallographic Studies of Nucleosome Core Particles containing Histone 'Sin' Mutants 分子名称: Histone H2A, Histone H2B, Histone H3, ... 著者 Muthurajan, U.M, Bao, Y, Forsberg, L.J, Edayathumangalam, R.S, Dyer, P.N, White, C.L, Luger, K. 登録日 2003-04-17 公開日 2004-02-24 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Crystal structures of histone Sin mutant nucleosomes reveal altered protein-DNA interactions EMBO J., 23, 2004
1TBD	SOLUTION STRUCTURE OF THE ORIGIN DNA BINDING DOMAIN OF SV40 T-ANTIGEN, NMR, MINIMIZED AVERAGE STRUCTURE 分子名称: SV40 T-ANTIGEN 著者 Luo, X, Sanford, D.G, Bullock, P.A, Bachovchin, W.W. 登録日 1996-11-04 公開日 1997-03-12 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution structure of the origin DNA-binding domain of SV40 T-antigen. Nat.Struct.Biol., 3, 1996
3H8O	Structure determination of DNA methylation lesions N1-meA and N3-meC in duplex DNA using a cross-linked host-guest system 分子名称: 5'-D(*CP*TP*GP*TP*AP*TP*(2YR)P*AP*TP*(MA7)P*GP*CP*G)-3', 5'-D(*TP*CP*GP*CP*TP*AP*TP*AP*AP*TP*AP*CP*A)-3', Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2, ... 著者 Lu, L, Yi, C, Jian, X, Zheng, Q. 登録日 2009-04-29 公開日 2010-03-31 最終更新日 2021-10-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure determination of DNA methylation lesions N1-meA and N3-meC in duplex DNA using a cross-linked protein-DNA system. Nucleic Acids Res., 38, 2010
2EZK	SOLUTION NMR STRUCTURE OF THE IBETA SUBDOMAIN OF THE MU END DNA BINDING DOMAIN OF PHAGE MU TRANSPOSASE, REGULARIZED MEAN STRUCTURE 分子名称: TRANSPOSASE 著者 Clore, G.M, Clubb, R.T, Schumaker, S, Gronenborn, A.M. 登録日 1997-10-04 公開日 1998-01-14 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the Mu end DNA-binding ibeta subdomain of phage Mu transposase: modular DNA recognition by two tethered domains. EMBO J., 16, 1997
1NH3	Human Topoisomerase I Ara-C Complex 分子名称: 5'-D(*(GNG)P*GP*AP*AP*AP*AP*AP*UP*UP*UP*UP*T)-3', 5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*UP*(UBB))-3', 5'-D(*AP*AP*AP*AP*AP*TP*UP*UP*UP*UP*CP*(CAR)P*AP*AP*GP*UP*CP*UP*UP*UP*UP*T)-3', ... 著者 Chrencik, J.E, Burgin, A.B, Pommier, Y, Stewart, L, Redinbo, M.R. 登録日 2002-12-18 公開日 2003-03-04 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural Impact of the Leukemia Drug 1-beta-D-Arabinofuranosylcytosine (Ara-C) on the Covalent Human Topoisomerase I-DNA Complex J.Biol.Chem., 278, 2003
6S1C	P3221 crystal form of the Ctf18-1-8/Pol2(1-528) complex 分子名称: Chromosome transmission fidelity protein 18, Chromosome transmission fidelity protein 8, DNA polymerase epsilon catalytic subunit A, ... 著者 Grabarczyk, D.B. 登録日 2019-06-18 公開日 2020-07-08 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (6.1 Å) 主引用文献 Ctf18-RFC and DNA Pol ε form a stable leading strand polymerase/clamp loader complex required for normal and perturbed DNA replication. Nucleic Acids Res., 48, 2020
6OZJ	Crystal structure of Mus musculus (Mm) Endonuclease V in complex with a 23mer RNA oligo containing an inosine in the absence of divalent cation 分子名称: 1,2-ETHANEDIOL, DNA/RNA (5'-R(P*CP*GP*GP*UP*AP*AP*CP*CP*C)-D(P*I)-R(P*AP*UP*AP*UP*GP*CP*AP*UP*GP*CP*AP*UP*U)-3'), Endonuclease V, ... 著者 Samara, N.L, Yang, W. 登録日 2019-05-15 公開日 2019-09-04 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.247 Å) 主引用文献 Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase. Mol.Cell, 76, 2019
6OZQ	Crystal structure of Mus musculus (Mm) Endonuclease V (K155M) in complex with a 23mer RNA oligo containing an inosine after a 100 min soak in 10 mM Mn2+ and K+ 分子名称: 1,2-ETHANEDIOL, DNA/RNA (5'-R(P*CP*GP*GP*UP*AP*AP*CP*CP*C)-D(P*I)-R(P*AP*UP*AP*UP*GP*CP*AP*UP*GP*CP*AP*UP*U)-3'), Endonuclease V, ... 著者 Samara, N.L, Yang, W. 登録日 2019-05-15 公開日 2019-09-04 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.153 Å) 主引用文献 Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase. Mol.Cell, 76, 2019
6OZP	Crystal structure of Mus musculus (Mm) Endonuclease V in complex with a 23mer RNA oligo containing an inosine after a 180 min soak in 10 mM Mn2+ 分子名称: 1,2-ETHANEDIOL, DNA/RNA (5'-R(*CP*GP*GP*UP*AP*AP*CP*CP*C)-D(P*I)-R(P*A)-3'), Endonuclease V, ... 著者 Samara, N.L, Yang, W. 登録日 2019-05-15 公開日 2019-09-04 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase. Mol.Cell, 76, 2019
1F2I	COCRYSTAL STRUCTURE OF SELECTED ZINC FINGER DIMER BOUND TO DNA 分子名称: 5'-D(*AP*TP*GP*GP*GP*CP*GP*CP*GP*CP*CP*CP*AP*T)-3', FUSION OF N-TERMINAL 17-MER PEPTIDE EXTENSION TO ZIF12, ZINC ION 著者 Wang, B.S, Grant, R.A, Pabo, C.O. 登録日 2000-05-25 公開日 2001-09-14 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Selected peptide extension contacts hydrophobic patch on neighboring zinc finger and mediates dimerization on DNA. Nat.Struct.Biol., 8, 2001
6OZS	Crystal structure of Mus musculus (Mm) Endonuclease V in complex with a 23mer RNA oligo containing an inosine after a 90 min soak in 10 mM Mg2+ 分子名称: 1,2-ETHANEDIOL, DNA/RNA (5'-R(*CP*GP*GP*UP*AP*AP*CP*CP*C)-D(P*I)-R(P*A)-3'), Endonuclease V, ... 著者 Samara, N.L, Yang, W. 登録日 2019-05-15 公開日 2019-09-04 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase. Mol.Cell, 76, 2019
4HLX	The crystal structure of the DNA binding domain of vIRF-1 from the oncogenic KSHV 分子名称: K9 著者 Hew, K, Venkatachalam, R. 登録日 2012-10-17 公開日 2013-03-13 最終更新日 2014-02-05 実験手法 X-RAY DIFFRACTION (2.379 Å) 主引用文献 The crystal structure of the DNA-binding domain of vIRF-1 from the oncogenic KSHV reveals a conserved fold for DNA binding and reinforces its role as a transcription factor. Nucleic Acids Res., 41, 2013
6VDK	CryoEM structure of HIV-1 conserved Intasome Core 分子名称: (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (25-MER), DNA (27-MER), ... 著者 Li, M, Chen, X, Craigie, R. 登録日 2019-12-27 公開日 2020-02-05 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 A Peptide Derived from Lens Epithelium-Derived Growth Factor Stimulates HIV-1 DNA Integration and Facilitates Intasome Structural Studies. J.Mol.Biol., 432, 2020
6OZK	Crystal structure of Mus musculus (Mm) Endonuclease V in complex with a 23mer RNA oligo containing an inosine after 68h soak in Ca2+ 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, DNA/RNA (5'-R(P*CP*GP*GP*UP*AP*AP*CP*CP*C)-D(P*I)-R(P*AP*UP*AP*UP*GP*CP*AP*UP*GP*CP*AP*UP*U)-3'), ... 著者 Samara, N.L, Yang, W. 登録日 2019-05-15 公開日 2019-09-04 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.104 Å) 主引用文献 Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase. Mol.Cell, 76, 2019
6VBW	Cryo-EM structure of Cascade-TniQ-dsDNA ternary complex 分子名称: Cas6, Cas7, Cas8, ... 著者 Jia, N, Patel, D.J. 登録日 2019-12-19 公開日 2020-01-29 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structure-function insights into the initial step of DNA integration by a CRISPR-Cas-Transposon complex. Cell Res., 30, 2020
6OZR	Crystal structure of Mus musculus (Mm) Endonuclease V in complex with a 23mer RNA oligo containing an inosine after a 15 min soak in 10 mM Mg2+ 分子名称: 1,2-ETHANEDIOL, DNA/RNA (23-MER), Endonuclease V, ... 著者 Samara, N.L, Yang, W. 登録日 2019-05-15 公開日 2019-09-04 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase. Mol.Cell, 76, 2019
6OZM	Crystal structure of Mus musculus (Mm) Endonuclease V in complex with a 23mer RNA oligo containing an inosine after a 10 min soak in 10 mM Mn2+ 分子名称: 1,2-ETHANEDIOL, DNA/RNA (5'-R(P*CP*GP*GP*UP*AP*AP*CP*CP*C)-D(P*I)-R(P*AP*UP*AP*UP*GP*CP*AP*UP*GP*CP*AP*UP*U)-3'), Endonuclease V, ... 著者 Samara, N.L, Yang, W. 登録日 2019-05-15 公開日 2019-09-04 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase. Mol.Cell, 76, 2019
6OZO	Crystal structure of Mus musculus (Mm) Endonuclease V in complex with a 23mer RNA oligo containing an inosine after a 30 min soak in 10 mM Mn2+ 分子名称: 1,2-ETHANEDIOL, DNA/RNA (5'-R(*CP*GP*GP*UP*AP*AP*CP*CP*C)-D(P*I)-R(P*AP*UP*AP*UP*GP*CP*AP*UP*GP*CP*AP*UP*U)-3'), Endonuclease V, ... 著者 Samara, N.L, Yang, W. 登録日 2019-05-15 公開日 2019-09-04 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.235 Å) 主引用文献 Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase. Mol.Cell, 76, 2019
4BHM	The crystal structure of MoSub1-DNA complex reveals a novel DNA binding mode 分子名称: 5'-D(*TP*TP*TP*TP*TP*TP*TP*TP)-3', MOSUB1 TRANSCRIPTION COFACTOR, SULFATE ION 著者 Huang, J, Liu, H, Zhao, Y, Huang, D, liu, J, Peng, Y. 登録日 2013-04-04 公開日 2014-04-23 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Substitution of Tryptophan 89 with Tyrosine Switches the DNA Binding Mode of Pc4. Sci.Rep., 5, 2015
4PY5	Thermovibrio ammonificans RNase H3 in complex with 19-mer RNA/DNA 分子名称: 5'-D(*GP*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*CP*GP*CP*AP*CP*TP*C)-3', 5'-R(*GP*AP*GP*UP*GP*CP*GP*AP*CP*AP*CP*CP*UP*GP*AP*UP*UP*CP*C)-3', GLYCEROL, ... 著者 Figiel, M, Nowotny, M. 登録日 2014-03-26 公開日 2014-07-30 最終更新日 2014-10-29 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of RNase H3-substrate complex reveals parallel evolution of RNA/DNA hybrid recognition. Nucleic Acids Res., 42, 2014
6OZN	Crystal structure of Mus musculus (Mm) Endonuclease V in complex with a 23mer RNA oligo containing an inosine after a 15 min soak in 10 mM Mn2+ 分子名称: 1,2-ETHANEDIOL, DNA/RNA (5'-R(P*CP*GP*GP*UP*AP*AP*CP*CP*C)-D(P*I)-R(P*AP*UP*AP*UP*GP*CP*AP*UP*GP*CP*AP*UP*U)-3'), Endonuclease V, ... 著者 Samara, N.L, Yang, W. 登録日 2019-05-15 公開日 2019-09-04 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase. Mol.Cell, 76, 2019
5U9D	Discovery of a potent BTK inhibitor with a novel binding mode using parallel selections with a DNA-encoded chemical library 分子名称: (R)-N-methyl-2-(3-((quinoxalin-6-ylamino)methyl)furan-2-carbonyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxamide, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ... 著者 Cuozzo, J.W, Centrella, P.A, Gikunju, D, Habeshian, S, Hupp, C.D, Keefe, A.D, Sigel, E, Soutter, H.H, Thomson, H.A, Zhang, Y, Clark, M.A. 登録日 2016-12-16 公開日 2017-01-18 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.33 Å) 主引用文献 Discovery of a Potent BTK Inhibitor with a Novel Binding Mode by Using Parallel Selections with a DNA-Encoded Chemical Library. Chembiochem, 18, 2017
7BSE	Crystal structure of a NIR-emitting DNA-stabilized Ag16 nanocluster (T5A mutant) 分子名称: CALCIUM ION, DNA (5'-D(*CP*AP*CP*CP*AP*AP*GP*CP*GP*A)-3'), SILVER ION 著者 Kondo, J, Cerretani, C, Vosch, T. 登録日 2020-03-30 公開日 2020-12-16 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Mutation of position 5 as a crystal engineering tool for a NIR-emitting DNA-stabilized Ag16 nanocluster. CrystEngComm, 22, 2020
7BSF	Crystal structure of a NIR-emitting DNA-stabilized Ag16 nanocluster (T5C mutant) 分子名称: CALCIUM ION, DNA (5'-D(*CP*AP*CP*CP*CP*AP*GP*CP*GP*A)-3'), SILVER ION 著者 Kondo, J, Cerretani, C, Vosch, T. 登録日 2020-03-30 公開日 2020-12-16 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Mutation of position 5 as a crystal engineering tool for a NIR-emitting DNA-stabilized Ag16 nanocluster. CrystEngComm, 22, 2020
3IH7	Crystal structure of catalytically active human 8-oxoguanine glycosylase distally crosslinked to guanine-containing DNA 分子名称: 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*G)-3', 5'-D(AP*TP*CP*TP*GP*GP*AP*CP*CP*TP*GP*CP*A)-3', N-glycosylase/DNA lyase 著者 Verdine, G.L, Crenshaw, C.M, Oo, K.S, Kutchukian, P.S. 登録日 2009-07-29 公開日 2010-11-03 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 A Catalytic Checkpoint in Base Excision by the Human 8-Oxoguanine DNA Glycosylase hOGG1 To be Published

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