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2VV0
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BU of 2vv0 by Molmil
hPPARgamma Ligand binding domain in complex with DHA
分子名称: DOCOSA-4,7,10,13,16,19-HEXAENOIC ACID, PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA
著者Itoh, T, Fairall, L, Schwabe, J.W.R.
登録日2008-06-02
公開日2008-08-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structural Basis for the Activation of Pparg by Oxidised Fatty Acids
Nat.Struct.Mol.Biol., 15, 2008
3DVS
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BU of 3dvs by Molmil
Proteinase K by LB nanotmplate method after the second step of high dose on ESRF ID14-2 beamline
分子名称: CALCIUM ION, Proteinase K
著者Pechkova, E, Tripathi, S.K, Nicolini, C.
登録日2008-07-20
公開日2009-07-07
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.02 Å)
主引用文献Radiation damage in protein structural characterization by Synchrotron Radiation: State of the art and Nanotechnology-based perspective
To be Published
3DWD
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BU of 3dwd by Molmil
Crystal structure of the ArfGAP domain of human ARFGAP1
分子名称: ADP-ribosylation factor GTPase-activating protein 1, UNKNOWN ATOM OR ION, ZINC ION
著者Nedyalkova, L, Tong, Y, Tempel, W, Landry, R, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Wilkstrom, M, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
登録日2008-07-22
公開日2008-08-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of the ArfGAP domain of human ARFGAP1
To be Published
3DV1
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BU of 3dv1 by Molmil
Crystal structure of human beta-secretase in complex with NVP-ARV999
分子名称: (2R,4S)-N-butyl-4-[(2S,5S,7R)-2,7-dimethyl-3,15-dioxo-1,4-diazacyclopentadecan-5-yl]-4-hydroxy-2-methylbutanamide, Beta-secretase 1
著者Rondeau, J.-M.
登録日2008-07-18
公開日2009-02-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Macrocyclic peptidomimetic beta-secretase (BACE-1) inhibitors with activity in vivo.
Bioorg.Med.Chem.Lett., 19, 2009
3LLK
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BU of 3llk by Molmil
Sulfhydryl Oxidase Fragment of Human QSOX1
分子名称: CITRATE ANION, FLAVIN-ADENINE DINUCLEOTIDE, Sulfhydryl oxidase 1
著者Alon, A, Fass, D.
登録日2010-01-29
公開日2010-03-31
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献QSOX contains a pseudo-dimer of functional and degenerate sulfhydryl oxidase domains.
Febs Lett., 584, 2010
3DYB
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BU of 3dyb by Molmil
proteinase K- digalacturonic acid complex
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, Proteinase K, ...
著者Larson, S.B, Day, J.S, McPherson, A, Cudney, R, Nguyen, C, Center for High-Throughput Structural Biology (CHTSB)
登録日2008-07-25
公開日2008-10-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.32 Å)
主引用文献High-resolution structure of proteinase K cocrystallized with digalacturonic acid.
Acta Crystallogr.,Sect.F, 65, 2009
3KGA
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BU of 3kga by Molmil
Crystal structure of MAPKAP kinase 2 (MK2) complexed with a potent 3-aminopyrazole ATP site inhibitor
分子名称: 6-{3-amino-1-[3-(1H-indol-6-yl)phenyl]-1H-pyrazol-4-yl}-3,4-dihydroisoquinolin-1(2H)-one, MAGNESIUM ION, MAP kinase-activated protein kinase 2
著者Kroemer, M, Velcicky, J, Izaac, A, Be, C, Huppertz, C, Pflieger, D, Schlapbach, A, Scheufler, C.
登録日2009-10-28
公開日2010-01-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Novel 3-aminopyrazole inhibitors of MK-2 discovered by scaffold hopping strategy.
Bioorg.Med.Chem.Lett., 20, 2010
3DM0
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BU of 3dm0 by Molmil
Maltose Binding Protein fusion with RACK1 from A. thaliana
分子名称: 1,2-ETHANEDIOL, Maltose-binding periplasmic protein fused with RACK1, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Ullah, H, Scappini, E.L, Moon, A.F, Williams, L.V, Armstrong, D.L, Pedersen, L.C.
登録日2008-06-30
公開日2008-09-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of a signal transduction regulator, RACK1, from Arabidopsis thaliana.
Protein Sci., 17, 2008
3GT4
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BU of 3gt4 by Molmil
Structure of proteinase K with the magic triangle I3C
分子名称: 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, SULFATE ION, proteinase K
著者Beck, T, Gruene, T, Sheldrick, G.M.
登録日2009-03-27
公開日2009-04-14
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献The magic triangle goes MAD: experimental phasing with a bromine derivative
Acta Crystallogr.,Sect.D, 66, 2010
3GYM
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BU of 3gym by Molmil
Structure of Prostasin in Complex with Aprotinin
分子名称: Pancreatic trypsin inhibitor, Prostasin
著者Spraggon, G, Hornsby, M, Shipway, A, Harris, J.L, Lesley, S.A.
登録日2009-04-03
公開日2009-05-05
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Active site conformational changes of prostasin provide a new mechanism of protease regulation by divalent cations.
Protein Sci., 18, 2009
3H1P
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BU of 3h1p by Molmil
Mature Caspase-7 I213A with DEVD-CHO inhibitor bound to active site
分子名称: Caspase-7, N-ACETYL-L-ALPHA-ASPARTYL-L-ALPHA-GLUTAMYL-N-[(2S)-1-CARBOXY-3-HYDROXYPROPAN-2-YL]-L-VALINAMIDE
著者Witkowski, W.A, Hardy, J.A.
登録日2009-04-13
公開日2009-06-30
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献L2' loop is critical for caspase-7 active site formation.
Protein Sci., 18, 2009
2WWE
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BU of 2wwe by Molmil
Crystal structure of the phox homology domain of human phosphoinositide-3-kinase-C2-gamma
分子名称: PHOSPHOINOSITIDE-3-KINASE, CLASS 2, GAMMA POLYPEPTIDE
著者Roos, A.K, Tresaugues, L, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Karlberg, T, Kotyenova, T, Kotzch, A, Kraulis, P, Markova, N, Moche, M, Nielsen, T.K, Nyman, T, Persson, C, Schuler, H, Schutz, P, Siponen, M.I, Svensson, L, Thorsell, A.G, Van Der Berg, S, Wahlberg, E, Weigelt, J, Welin, M, Wisniewska, M, Nordlund, P, Structural Genomics Consortium (SGC)
登録日2009-10-22
公開日2009-11-03
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Crystal Structure of the Phox Homology Domain of Human Phosphoinositide-3-Kinase-C2-Gamma
To be Published
3KDF
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BU of 3kdf by Molmil
X-ray Crystal Structure of the Human Replication Protein A Complex from Wheat Germ Cell Free Expression
分子名称: 1,2-ETHANEDIOL, Replication protein A 14 kDa subunit, Replication protein A 32 kDa subunit
著者Burgie, E.S, Bingman, C.A, Phillips Jr, G.N, Fox, B.G, Makino, S.-I, Center for Eukaryotic Structural Genomics (CESG)
登録日2009-10-22
公開日2009-12-01
最終更新日2021-10-13
実験手法X-RAY DIFFRACTION (1.975 Å)
主引用文献X-ray Crystal Structure of the Human Replication Protein A Complex from Wheat Germ Cell Free Expression
To be Published
3KGT
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BU of 3kgt by Molmil
V30M mutant human transthyretin (TTR) complexed with genistein (V30M:GEN) pH 7.5
分子名称: GENISTEIN, Transthyretin
著者Trivella, D.B, Polikarpov, I.
登録日2009-10-29
公開日2010-03-23
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Conformational differences between the wild type and V30M mutant transthyretin modulate its binding to genistein: implications to tetramer stability and ligand-binding.
J.Struct.Biol., 170, 2010
2WQE
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BU of 2wqe by Molmil
Structure of S155R Aurora-A somatic mutant
分子名称: ADENOSINE-5'-DIPHOSPHATE, SERINE/THREONINE-PROTEIN KINASE 6
著者Bibby, R, Bayliss, R.
登録日2009-08-20
公開日2009-09-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A Cancer Associated Aurora-A Mutant is Mislocalised and Misregulated due to Loss of Interaction with Tpx2.
J.Biol.Chem., 284, 2009
3HBV
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BU of 3hbv by Molmil
PrtC methionine mutants: M226A in-house
分子名称: CALCIUM ION, CHLORIDE ION, Secreted protease C, ...
著者Oberholzer, A.E, Bumann, M, Hege, T, Russo, S, Baumann, U.
登録日2009-05-05
公開日2009-06-30
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Metzincin's canonical methionine is responsible for the structural integrity of the zinc-binding site
Biol.Chem., 390, 2009
3KGS
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BU of 3kgs by Molmil
V30M mutant human transthyretin (TTR) (apoV30M) pH 7.5
分子名称: Transthyretin
著者Trivella, D.B, Polikarpov, I.
登録日2009-10-29
公開日2010-03-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Conformational differences between the wild type and V30M mutant transthyretin modulate its binding to genistein: implications to tetramer stability and ligand-binding.
J.Struct.Biol., 170, 2010
3GRP
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BU of 3grp by Molmil
2.1 Angstrom crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase from Bartonella henselae
分子名称: 3-oxoacyl-(Acyl carrierprotein) reductase
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2009-03-26
公開日2009-04-07
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献2.1 Angstrom crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase from Bartonella henselae
To be Published
3I5N
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BU of 3i5n by Molmil
Crystal structure of c-Met with triazolopyridazine inhibitor 13
分子名称: 7-methoxy-N-[(6-phenyl[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl]-1,5-naphthyridin-4-amine, Hepatocyte growth factor receptor
著者Bellon, S.F, Whittington, D.A, Long, A.M, Boezio, A.A.
登録日2009-07-06
公開日2010-01-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Discovery and optimization of potent and selective triazolopyridazine series of c-Met inhibitors
Bioorg.Med.Chem.Lett., 19, 2009
3I5R
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BU of 3i5r by Molmil
PI3K SH3 domain in complex with a peptide ligand
分子名称: Peptide ligand, Phosphatidylinositol 3-kinase regulatory subunit alpha
著者Batra-Safferling, R, Granzin, J, Modder, S, Hoffmann, S, Willbold, D.
登録日2009-07-06
公開日2010-03-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural studies of the phosphatidylinositol 3-kinase (PI3K) SH3 domain in complex with a peptide ligand: role of the anchor residue in ligand binding.
Biol.Chem., 391, 2010
3I5S
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BU of 3i5s by Molmil
Crystal structure of PI3K SH3
分子名称: Phosphatidylinositol 3-kinase regulatory subunit alpha, SULFATE ION
著者Batra-Safferling, R, Granzin, J, Modder, S, Hoffmann, S, Willbold, D.
登録日2009-07-06
公開日2010-03-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural studies of the phosphatidylinositol 3-kinase (PI3K) SH3 domain in complex with a peptide ligand: role of the anchor residue in ligand binding.
Biol.Chem., 391, 2010
3I7P
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Crystal Structure of DDB1 in Complex with the H-Box Motif of WDR40A
分子名称: DNA damage-binding protein 1, WD repeat-containing protein 40A
著者Li, T, Robert, E.I, Breugel, P.C.V, Strubin, M, Zheng, N.
登録日2009-07-08
公開日2009-12-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery.
Nat.Struct.Mol.Biol., 17, 2010
3IGQ
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BU of 3igq by Molmil
Crystal structure of the extracellular domain of a bacterial pentameric ligand-gated ion channel
分子名称: ACETIC ACID, CHLORIDE ION, Glr4197 protein, ...
著者Nury, H, Delarue, M.
登録日2009-07-28
公開日2009-12-08
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the extracellular domain of a bacterial ligand-gated ion channel
J.Mol.Biol., 395, 2010
3GHD
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BU of 3ghd by Molmil
Crystal structure of a cystathionine beta-synthase domain protein fused to a Zn-ribbon-like domain
分子名称: a cystathionine beta-synthase domain protein fused to a Zn-ribbon-like domain
著者Dong, A, Xu, X, Chruszcz, M, Brown, G, Proudfoot, M, Edwards, A.M, Joachimiak, A, Minor, W, Savchenko, A, Yaleunin, A, Midwest Center for Structural Genomics (MCSG)
登録日2009-03-03
公開日2009-03-31
最終更新日2022-04-13
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Crystal structure of a cystathionine beta-synthase domain protein fused to a Zn-ribbon-like domain
To be Published
3GIS
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BU of 3gis by Molmil
Crystal Structure of Na-free Thrombin in Complex with Thrombomodulin
分子名称: CALCIUM ION, Prothrombin, SULFATE ION, ...
著者Adams, T.E, Huntington, J.A.
登録日2009-03-06
公開日2009-08-18
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Molecular basis of thrombomodulin activation of slow thrombin
J.Thromb.Haemost., 7, 2009

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