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2FB4
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DIR PRIMAERSTRUKTUR DES KRISTALLISIERBAREN MONOKLONALEN IMMUNOGLOBULINS IGG1 KOL. II. AMINOSAEURESEQUENZ DER L-KETTE, LAMBDA-TYP, SUBGRUPPE I (GERMAN)
分子名称: IGG1-LAMBDA KOL FAB (HEAVY CHAIN), IGG1-LAMBDA KOL FAB (LIGHT CHAIN)
著者Marquart, M, Huber, R.
登録日1989-04-18
公開日1989-07-12
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The primary structure of crystallizable monoclonal immunoglobulin IgG1 Kol. II. Amino acid sequence of the L-chain, gamma-type, subgroup I
Biol.Chem.Hoppe-Seyler, 370, 1989
1M05
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HLA B8 in complex with an Epstein Barr Virus determinant
分子名称: Beta-2-microglobulin, CADMIUM ION, EBNA-3 nuclear protein, ...
著者Kjer-Nielsen, L, Clements, C.S, Brooks, A.G, Purcell, A.W, Fontes, M.R, McCluskey, J, Rossjohn, J.
登録日2002-06-11
公開日2003-09-02
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The structure of HLA-B8 complexed to an immunodominant viral determinant: peptide-induced conformational changes and a mode of MHC class I dimerization.
J.IMMUNOL., 169, 2003
3GSV
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Crystal structure of the binary complex between HLA-A2 and HCMV NLV-M5Q peptide variant
分子名称: Beta-2-microglobulin, HCMV pp65 fragment 495-503, variant M5Q (NLVPQVATV), ...
著者Reiser, J.-B, Saulquin, X, Gras, S, Debeaupuis, E, Echasserieau, K, Kissenpfennig, A, Legoux, F, Chouquet, A, Le Gorrec, M, Machillot, P, Neveu, B, Thielens, N, Malissen, B, Bonneville, M, Housset, D.
登録日2009-03-27
公開日2009-08-04
最終更新日2021-10-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural bases for the affinity-driven selection of a public TCR against a dominant human cytomegalovirus epitope.
J.Immunol., 183, 2009
4O2F
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A peptide complexed with HLA-B*3901
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-39 alpha chain, ...
著者Sun, M, Liu, J, Qi, J, Tefsen, B, Shi, Y, Yan, J, Gao, G.F.
登録日2013-12-17
公開日2014-07-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.901 Å)
主引用文献N alpha-terminal acetylation for T cell recognition: molecular basis of MHC class I-restricted n alpha-acetylpeptide presentation
J.Immunol., 192, 2014
5Y91
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The structure of the MHC class I molecule of bony fishes provides insights into the conserved nature of the antigen-presenting system
分子名称: Beta-2-microglobulin, MHC class I antigen, PEPTIDE PHE-ALA-ASN-PHE-CYS-LEU-MET-MET-ILE
著者Zhaosan, C, Nianzhi, Z, Chun, X.
登録日2017-08-22
公開日2017-09-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.901 Å)
主引用文献Crystal structure of bony fish MHC class I complex at 1.9 Angstroms resolution.
To Be Published
6PTE
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Crystal Structure of ILNAMITKI peptide bound to HLA-A2
分子名称: Beta-2-microglobulin, GLYCEROL, HAUS augmin-like complex subunit 3, ...
著者Smith, A.R, Arbuiso, A, Keller, G.L.J, Baker, B.M.
登録日2019-07-15
公開日2019-09-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.901 Å)
主引用文献Structure Based Prediction of Neoantigen Immunogenicity.
Front Immunol, 10, 2019
6UBI
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N123-VRC34.05 HIV neutralizing antibody in complex with HIV fusion peptide residue 512-519
分子名称: HIV fusion peptide 512-519, VRC34.05 heavy chain, VRC34.05 light chain
著者Xu, K, Liu, K, Kwong, P.D.
登録日2019-09-11
公開日2020-03-18
最終更新日2020-04-22
実験手法X-RAY DIFFRACTION (1.903 Å)
主引用文献VRC34-Antibody Lineage Development Reveals How a Required Rare Mutation Shapes the Maturation of a Broad HIV-Neutralizing Lineage.
Cell Host Microbe, 27, 2020
6R0E
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Structure of F11TCR in complex with DR1 MHC Class II presenting PKYVKQNTLKLAT
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, F11-TCR Alpha Chain, ...
著者Rizkallah, P.J, Greenshields-Watson, A.L.
登録日2019-03-12
公開日2020-07-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献CD4+T Cells Recognize Conserved Influenza A Epitopes through Shared Patterns of V-Gene Usage and Complementary Biochemical Features.
Cell Rep, 32, 2020
4X6F
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CD1a binary complex with sphingomyelin
分子名称: (4S,7S,23Z)-4-hydroxy-7-[(1S,2Z)-1-hydroxyhexadec-2-en-1-yl]-N,N,N-trimethyl-9-oxo-3,5-dioxa-8-aza-4-phosphadotriacont- 23-en-1-aminium 4-oxide, Beta-2-microglobulin, T-cell surface glycoprotein CD1a
著者Birkinshaw, R.W, Rossjohn, J.
登録日2014-12-08
公開日2015-02-04
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献alpha beta T cell antigen receptor recognition of CD1a presenting self lipid ligands.
Nat.Immunol., 16, 2015
5IB3
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Crystal structure of HLA-B*27:05 complexed with the self-peptide pVIPR and Copper
分子名称: Beta-2-microglobulin, COPPER (II) ION, GLYCEROL, ...
著者Janke, R, Ballaschk, M, Schmieder, P, Uchanska-Ziegler, B, Ziegler, A, Loll, B.
登録日2016-02-22
公開日2017-02-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Metal-triggered conformational reorientation of a self-peptide bound to a disease-associated HLA-B*27 subtype.
J.Biol.Chem., 2019
5IB1
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Crystal structure of HLA-B*27:05 complexed with the self-peptide pVIPR measured at 295 K
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-27 alpha chain, ...
著者Janke, R, Ballaschk, M, Schmieder, P, Uchanska-Ziegler, B, Ziegler, A, Loll, B.
登録日2016-02-22
公開日2017-02-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Metal-triggered conformational reorientation of a self-peptide bound to a disease-associated HLA-B*27 subtype.
J.Biol.Chem., 2019
4DZ8
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human IgG1 Fc fragment Heterodimer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region
著者Strop, P.
登録日2012-02-29
公開日2012-08-01
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Generating Bispecific Human IgG1 and IgG2 Antibodies from Any Antibody Pair.
J.Mol.Biol., 420, 2012
1LK3
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ENGINEERED HUMAN INTERLEUKIN-10 MONOMER COMPLEXED TO 9D7 FAB FRAGMENT
分子名称: 9D7 Heavy Chain, 9D7 Light Chain, Interleukin-10
著者Josephson, K, Jones, B.C, Walter, L.J, DiGiacomo, R, Indelicato, S.R, Walter, M.R.
登録日2002-04-23
公開日2002-07-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Noncompetitive antibody neutralization of IL-10 revealed by protein engineering and x-ray crystallography.
Structure, 10, 2002
3CC5
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H-2Db complex with human gp100
分子名称: Beta-2-microglobulin, GLYCEROL, H-2 class I histocompatibility antigen, ...
著者Badia-Martinez, D, Achour, A.
登録日2008-02-24
公開日2009-03-03
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Design of agonistic altered peptides for the robust induction of CTL directed towards H-2Db in complex with the melanoma-associated epitope gp100.
Cancer Res., 69, 2009
7XF3
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The structure of HLA-B*1501/BM58-66AF9
分子名称: 9-mer peptide from Matrix protein 1, Beta-2-microglobulin, MHC class I antigen
著者Zhao, Y.Z, Xiao, W.L, Wu, Y.N, Fan, W.F, Yue, C, Zhang, Q.X, Zhang, D.N, Yuan, X.J, Yao, S.J, Liu, S, Li, M, Wang, P.Y, Zhang, H.J, Zhang, J, Zhao, M, Zheng, X.Q, Liu, W.J, Gao, G.F, Liu, W.L.
登録日2022-03-31
公開日2023-02-08
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Parallel T Cell Immunogenic Regions in Influenza B and A Viruses with Distinct Nuclear Export Signal Functions: The Balance between Viral Life Cycle and Immune Escape.
J Immunol., 210, 2023
4JFP
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A2 HLA complex with G4A heteroclitic variant of Melanoma peptide
分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-2-microglobulin, ...
著者Rizkallah, P.J, Cole, D.K, Madura, F, Sewell, A.K.
登録日2013-02-28
公開日2013-05-29
最終更新日2013-07-17
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献T-cell receptor specificity maintained by altered thermodynamics.
J.Biol.Chem., 288, 2013
6I8C
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Crystal structure of the murine beta-2-microglobulin.
分子名称: Beta-2-microglobulin, TRIETHYLENE GLYCOL
著者Achour, A, Sandalova, T, Ricagno, S, Sun, R.
登録日2018-11-20
公開日2019-10-02
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Biochemical and biophysical comparison of human and mouse beta-2 microglobulin reveals the molecular determinants of low amyloid propensity.
Febs J., 287, 2020
4LKX
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Humanized antibody 4B12 Fab complexed with a CemX segment
分子名称: CemX segment, Fab fragment heavy chain, Fab fragment light chain
著者Chu, H.M, Wright, J, Chan, Y.H, Lin, C.J, Chang, T.W, Lim, C.
登録日2013-07-09
公開日2014-01-29
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Two potential therapeutic antibodies bind to a peptide segment of membrane-bound IgE in different conformations.
Nat Commun, 5, 2014
6PUF
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Structure of human MAIT A-F7 TCR in complex with human MR1-5'D-5-OP-RU
分子名称: 1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, Beta-2-microglobulin, GLYCEROL, ...
著者Awad, W, Rossjohn, J.
登録日2019-07-18
公開日2020-02-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献The molecular basis underpinning the potency and specificity of MAIT cell antigens.
Nat.Immunol., 21, 2020
4L4J
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Crystal structure of fc-fragment of human IgG2-Sigma antibody
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
著者Teplyakov, A, Malia, T, Gillilang, G.
登録日2013-06-07
公開日2013-08-28
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献An engineered Fc variant of an IgG eliminates all immune effector functions via structural perturbations.
Methods, 65, 2014
6PUJ
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Structure of human MAIT A-F7 TCR in complex with human MR1-3`OH-Propyl-5-OP-U
分子名称: 6-[(3-hydroxypropyl)amino]-5-[(E)-(2-oxopropylidene)amino]pyrimidine-2,4(1H,3H)-dione, Beta-2-microglobulin, CHLORIDE ION, ...
著者Awad, W, Keller, A.N, Rossjohn, J.
登録日2019-07-18
公開日2020-02-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献The molecular basis underpinning the potency and specificity of MAIT cell antigens.
Nat.Immunol., 21, 2020
2IAL
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Structural basis for recognition of mutant self by a tumor-specific, MHC class II-restricted TCR
分子名称: CD4+ T cell receptor E8 alpha chain, CD4+ T cell receptor E8 beta chain
著者Deng, L, Langley, R.J, Mariuzza, R.A.
登録日2006-09-08
公開日2007-04-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor
Nat.Immunol., 8, 2007
4U1I
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HLA class I micropolymorphisms determine peptide-HLA landscape and dictate differential HIV-1 escape through identical epitopes
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GAG protein, ...
著者Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K.
登録日2014-07-15
公開日2015-04-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Retrovirology, 12, 2015
3FQW
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Phosphorylation of self-peptides alters Human Leukocyte Antigen Class I-restricted antigen presentation and generates tumor specific epitopes
分子名称: Beta-2-microglobulin, CADMIUM ION, COBALT (II) ION, ...
著者Petersen, J, Rossjohn, J.
登録日2009-01-07
公開日2009-03-03
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.927 Å)
主引用文献Phosphorylated self-peptides alter human leukocyte antigen class I-restricted antigen presentation and generate tumor-specific epitopes
Proc.Natl.Acad.Sci.Usa, 106, 2009
3MR9
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Crystal Structure of MHC class I HLA-A2 molecule complexed with HCMV pp65-495-503 nonapeptide M5A variant
分子名称: 9-meric peptide from Tegument protein pp65, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Reiser, J.-B, Le Gorrec, M, Chouquet, A, Debeaupuis, E, Echasserieau, K, Saulquin, X, Bonneville, M, Housset, D.
登録日2010-04-29
公開日2011-05-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Crystal Structure of MHC class I HLA-A2 molecule complexed with short peptide
To be Published

222415

件を2024-07-10に公開中

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