7NEQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7neq by Molmil](/molmil-images/mine/7neq) | Structure of tariquidar-bound ABCG2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5D3(Fab) heavy chain variable domain, 5D3(Fab) light chain variable domain, ... | 著者 | Kowal, J, Locher, K. | 登録日 | 2021-02-04 | 公開日 | 2021-04-21 | 最終更新日 | 2021-05-12 | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | 主引用文献 | Structural Basis of Drug Recognition by the Multidrug Transporter ABCG2. J.Mol.Biol., 433, 2021
|
|
7NHL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7nhl by Molmil](/molmil-images/mine/7nhl) | VgaA-LC, an antibiotic resistance ABCF, in complex with 70S ribosome from Staphylococcus aureus | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Crowe-McAuliffe, C, Murina, V, Hauryliuk, V, Wilson, D.N. | 登録日 | 2021-02-10 | 公開日 | 2021-05-05 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens. Nat Commun, 12, 2021
|
|
7NHN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7nhn by Molmil](/molmil-images/mine/7nhn) | VgaL, an antibiotic resistance ABCF, in complex with 70S ribosome from Listeria monocytogenes | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Crowe-McAuliffe, C, Turnbull, K.J, Hauryliuk, V, Wilson, D.N. | 登録日 | 2021-02-10 | 公開日 | 2021-05-05 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens. Nat Commun, 12, 2021
|
|
7NIU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7niu by Molmil](/molmil-images/mine/7niu) | |
7NIV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7niv by Molmil](/molmil-images/mine/7niv) | Nanodisc reconstituted human ABCB4 in complex with 4B1-Fab and QA2-Fab (phosphatidylcholine-bound, occluded conformation) | 分子名称: | 1,2-DILINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 4B1 Fab-fragment light chain, CHOLESTEROL, ... | 著者 | Nosol, K, Locher, K.P. | 登録日 | 2021-02-14 | 公開日 | 2021-08-25 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structures of ABCB4 provide insight into phosphatidylcholine translocation. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7NNU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7nnu by Molmil](/molmil-images/mine/7nnu) | Cryo-EM structure of the folate-specific ECF transporter complex in MSP2N2 lipid nanodiscs | 分子名称: | Conserved hypothetical membrane protein, Energy-coupling factor transporter ATP-binding protein EcfA1, Energy-coupling factor transporter ATP-binding protein EcfA2, ... | 著者 | Thangaratnarajah, C, Rheinberger, J, Paulino, C, Slotboom, D.J. | 登録日 | 2021-02-25 | 公開日 | 2021-08-18 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Insights into the bilayer-mediated toppling mechanism of a folate-specific ECF transporter by cryo-EM. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7NNT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7nnt by Molmil](/molmil-images/mine/7nnt) | Cryo-EM structure of the folate-specific ECF transporter complex in DDM micelles | 分子名称: | Energy-coupling factor transporter ATP-binding protein EcfA1, Energy-coupling factor transporter ATP-binding protein EcfA2, Energy-coupling factor transporter transmembrane protein EcfT, ... | 著者 | Thangaratnarajah, C, Rheinberger, J, Paulino, C, Slotboom, D.J. | 登録日 | 2021-02-25 | 公開日 | 2021-08-18 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Insights into the bilayer-mediated toppling mechanism of a folate-specific ECF transporter by cryo-EM. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7NIW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7niw by Molmil](/molmil-images/mine/7niw) | Nanodisc reconstituted human ABCB4 in complex with 4B1-Fab (posaconazole-bound, inward-open conformation) | 分子名称: | 1,2-DILINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 4B1 Fab-fragment heavy chain, 4B1 Fab-fragment light chain, ... | 著者 | Nosol, K, Locher, K.P. | 登録日 | 2021-02-14 | 公開日 | 2021-08-25 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structures of ABCB4 provide insight into phosphatidylcholine translocation. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7N5B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7n5b by Molmil](/molmil-images/mine/7n5b) | Structure of AtAtm3 in the outward-facing conformation | 分子名称: | ABC transporter B family member 25, mitochondrial, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Fan, C, Rees, D.C. | 登録日 | 2021-06-05 | 公開日 | 2022-04-13 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Glutathione binding to the plant At Atm3 transporter and implications for the conformational coupling of ABC transporters. Elife, 11, 2022
|
|
7N58
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7n58 by Molmil](/molmil-images/mine/7n58) | |
7N59
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7n59 by Molmil](/molmil-images/mine/7n59) | |
7N5A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7n5a by Molmil](/molmil-images/mine/7n5a) | Structure of AtAtm3 in the closed conformation | 分子名称: | ABC transporter B family member 25, mitochondrial, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Fan, C, Rees, D.C. | 登録日 | 2021-06-05 | 公開日 | 2022-04-13 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.95 Å) | 主引用文献 | Glutathione binding to the plant At Atm3 transporter and implications for the conformational coupling of ABC transporters. Elife, 11, 2022
|
|
7O0Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7o0y by Molmil](/molmil-images/mine/7o0y) | ABC transporter NosDFY, nucleotide-free in GDN | 分子名称: | MAGNESIUM ION, Probable ABC transporter ATP-binding protein NosF, Probable ABC transporter binding protein NosD, ... | 著者 | Mueller, C, Zhang, L, Lu, W, Einsle, O, Du, J. | 登録日 | 2021-03-28 | 公開日 | 2022-04-13 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
|
|
7O16
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7o16 by Molmil](/molmil-images/mine/7o16) | ABC transporter NosDFY, nucleotide-free in lipid nanodisc, R-domain 3 | 分子名称: | MAGNESIUM ION, Probable ABC transporter ATP-binding protein NosF, Probable ABC transporter binding protein NosD, ... | 著者 | Mueller, C, Zhang, L, Lu, W, Einsle, O, Du, J. | 登録日 | 2021-03-28 | 公開日 | 2022-04-13 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY | 主引用文献 | Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
|
|
7O15
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7o15 by Molmil](/molmil-images/mine/7o15) | ABC transporter NosDFY, nucleotide-free in lipid nanodisc, R-domain 2 | 分子名称: | MAGNESIUM ION, Probable ABC transporter ATP-binding protein NosF, Probable ABC transporter binding protein NosD, ... | 著者 | Mueller, C, Zhang, L, Lu, W, Einsle, O, Du, J. | 登録日 | 2021-03-28 | 公開日 | 2022-04-13 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY | 主引用文献 | Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
|
|
7O14
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7o14 by Molmil](/molmil-images/mine/7o14) | ABC transporter NosDFY, nucleotide-free in lipid nanodisc, R-domain 1 | 分子名称: | MAGNESIUM ION, Probable ABC transporter ATP-binding protein NosF, Probable ABC transporter binding protein NosD, ... | 著者 | Mueller, C, Zhang, L, Lu, W, Einsle, O, Du, J. | 登録日 | 2021-03-28 | 公開日 | 2022-04-13 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY | 主引用文献 | Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
|
|
7O12
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7o12 by Molmil](/molmil-images/mine/7o12) | ABC transporter NosDFY, AMPPNP-bound in GDN | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Probable ABC transporter ATP-binding protein NosF, ... | 著者 | Mueller, C, Zhang, L, Lu, W, Einsle, O, Du, J. | 登録日 | 2021-03-28 | 公開日 | 2022-04-13 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
|
|
7O11
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7o11 by Molmil](/molmil-images/mine/7o11) | ABC transporter NosDFY, nucleotide-free in GDN, R-domain 1 | 分子名称: | MAGNESIUM ION, Probable ABC transporter ATP-binding protein NosF, Probable ABC transporter binding protein NosD, ... | 著者 | Mueller, C, Zhang, L, Lu, W, Einsle, O, Du, J. | 登録日 | 2021-03-28 | 公開日 | 2022-04-13 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
|
|
7O10
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7o10 by Molmil](/molmil-images/mine/7o10) | ABC transporter NosDFY, nucleotide-free in GDN, R-domain 2 | 分子名称: | MAGNESIUM ION, Probable ABC transporter ATP-binding protein NosF, Probable ABC transporter binding protein NosD, ... | 著者 | Mueller, C, Zhang, L, Lu, W, Einsle, O, Du, J. | 登録日 | 2021-03-28 | 公開日 | 2022-04-13 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
|
|
7O17
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7o17 by Molmil](/molmil-images/mine/7o17) | ABC transporter NosDFY E154Q, ATP-bound in lipid nanodisc | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Probable ABC transporter ATP-binding protein NosF, ... | 著者 | Mueller, C, Zhang, L, Lu, W, Einsle, O, Du, J. | 登録日 | 2021-03-28 | 公開日 | 2022-04-13 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
|
|
7OCY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ocy by Molmil](/molmil-images/mine/7ocy) | Enterococcus faecalis EfrCD in complex with a nanobody | 分子名称: | ABC transporter ATP-binding protein, Nanobody | 著者 | Ehrenbolger, K, Hutter, C.A.J, Meier, G, Seeger, M.A, Barandun, J. | 登録日 | 2021-04-28 | 公開日 | 2022-05-18 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (4.25 Å) | 主引用文献 | Deep mutational scan of a drug efflux pump reveals its structure-function landscape. Nat.Chem.Biol., 19, 2023
|
|
7O0Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7o0z by Molmil](/molmil-images/mine/7o0z) | ABC transporter NosFY, nucleotide-free in GDN | 分子名称: | Probable ABC transporter ATP-binding protein NosF, Probable ABC transporter permease protein NosY | 著者 | Mueller, C, Zhang, L, Lu, W, Einsle, O, Du, J. | 登録日 | 2021-03-28 | 公開日 | 2022-11-02 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
|
|
7O13
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7o13 by Molmil](/molmil-images/mine/7o13) | ABC transporter NosDFY, nucleotide-free in lipid nanodisc | 分子名称: | MAGNESIUM ION, Probable ABC transporter ATP-binding protein NosF, Probable ABC transporter binding protein NosD, ... | 著者 | Mueller, C, Zhang, L, Lu, W, Einsle, O, Du, J. | 登録日 | 2021-03-28 | 公開日 | 2022-11-02 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
|
|
7OJH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ojh by Molmil](/molmil-images/mine/7ojh) | ABCG2 topotecan turnover-1 state | 分子名称: | (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE, ADENOSINE-5'-TRIPHOSPHATE, Broad substrate specificity ATP-binding cassette transporter ABCG2, ... | 著者 | Yu, Q, Ni, D, Kowal, J, Manolaridis, I, Jackson, S.M, Stahlberg, H, Locher, K.P. | 登録日 | 2021-05-15 | 公開日 | 2021-07-21 | 最終更新日 | 2021-07-28 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structures of ABCG2 under turnover conditions reveal a key step in the drug transport mechanism. Nat Commun, 12, 2021
|
|
7OJ8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7oj8 by Molmil](/molmil-images/mine/7oj8) | ABCG2 E1S turnover-2 state | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Broad substrate specificity ATP-binding cassette transporter ABCG2, CHOLESTEROL, ... | 著者 | Ni, D, Yu, Q, Kowal, J, Manolaridis, I, Jackson, S.M, Stahlberg, H, Locher, K.P. | 登録日 | 2021-05-14 | 公開日 | 2021-07-21 | 最終更新日 | 2021-07-28 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structures of ABCG2 under turnover conditions reveal a key step in the drug transport mechanism. Nat Commun, 12, 2021
|
|