7NEQ
Structure of tariquidar-bound ABCG2
Summary for 7NEQ
Entry DOI | 10.2210/pdb7neq/pdb |
EMDB information | 12290 |
Descriptor | ATP-binding cassette sub-family G member 2, 5D3(Fab) light chain variable domain, 5D3(Fab) heavy chain variable domain, ... (8 entities in total) |
Functional Keywords | abcg2, tariquidar, substrate, abc transporter, anticancer drugs, cavity 1, cryo-em, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 242531.96 |
Authors | Kowal, J.,Locher, K. (deposition date: 2021-02-04, release date: 2021-04-21, Last modification date: 2021-05-12) |
Primary citation | Kowal, J.,Ni, D.,Jackson, S.M.,Manolaridis, I.,Stahlberg, H.,Locher, K.P. Structural Basis of Drug Recognition by the Multidrug Transporter ABCG2. J.Mol.Biol., 433:166980-166980, 2021 Cited by PubMed: 33838147DOI: 10.1016/j.jmb.2021.166980 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.12 Å) |
Structure validation
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