7NEQ
Structure of tariquidar-bound ABCG2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | ATP-binding cassette sub-family G member 2 | polymer | 655 | 72385.9 | 2 | UniProt (Q9UNQ0) Pfam (PF00005) Pfam (PF19055) Pfam (PF01061) In PDB | Homo sapiens (human) | Breast cancer resistance protein,CDw338,Mitoxantrone resistance-associated protein,Placenta-specific ATP-binding cassette transporter,Urate exporter |
| 2 | C, E | 5D3(Fab) light chain variable domain | polymer | 214 | 23594.0 | 2 | Mus musculus (house mouse) | ||
| 3 | D, F | 5D3(Fab) heavy chain variable domain | polymer | 221 | 23843.6 | 2 | Mus musculus (house mouse) | ||
| 4 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 5 | A | [(2~{S})-3-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-2-decanoyloxy-propyl] octadecanoate | non-polymer | 635.9 | 1 | Chemie (U9N) | |||
| 6 | A, B | CHOLESTEROL | non-polymer | 386.7 | 3 | Chemie (CLR) | |||
| 7 | B | tariquidar | non-polymer | 646.7 | 1 | Chemie (R1H) | |||
| 8 | water | water | 18.0 | 16 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 239647.0 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 2885.0 | |
| All* | Total formula weight | 242532.0 |
