PDB: 17012 件ウェブページステータス検索Chemie searchBIRD

---

2OYQ	Crystal structure of RB69 gp43 in complex with DNA with 5-NIMP opposite an abasic site analog 分子名称: 1-{2-DEOXY-5-O-[(R)-HYDROXY{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}PHOSPHORYL]-BETA-D-ERYTHRO-PENTOFURANOSYL}-5-NITRO -1H-INDOLE, DNA polymerase, MAGNESIUM ION, ... 著者 Zahn, K.E, Belrhali, H, Wallace, S.S, Doublie, S. 登録日 2007-02-22 公開日 2007-10-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.86 Å) 主引用文献 Caught bending the a-rule: crystal structures of translesion DNA synthesis with a non-natural nucleotide. Biochemistry, 46, 2007
3QOQ	Crystal Structure of the Transcription Factor AmrZ in Complex with the 18 Base Pair amrZ1 Binding Site 分子名称: Alginate and motility regulator Z, DNA (5'-D(*AP*CP*TP*GP*GP*CP*AP*AP*AP*AP*CP*GP*CP*CP*GP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*CP*GP*GP*CP*GP*TP*TP*TP*TP*GP*CP*CP*AP*GP*T)-3') 著者 Pryor Jr, E.E, Wozniak, D.J, Hollis, T. 登録日 2011-02-10 公開日 2012-02-15 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 The Transcription Factor AmrZ Utilizes Multiple DNA Binding Modes to Recognize Activator and Repressor Sequences of Pseudomonas aeruginosa Virulence Genes. Plos Pathog., 8, 2012
3QAQ	Crystal structure of PI3K-gamma in complex with triazine-benzimidazole 1 分子名称: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, SULFATE ION, [(4-{2-[(3-hydroxyphenyl)amino]-1H-benzimidazol-1-yl}-1,3,5-triazin-2-yl)amino]acetonitrile 著者 Whittington, D.A, Tang, J, Yakowec, P. 登録日 2011-01-11 公開日 2011-03-30 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Discovery of triazine-benzimidazoles as selective inhibitors of mTOR. Bioorg.Med.Chem.Lett., 21, 2011
2LDR	Solution structure of Helix-RING domain of Cbl-b in the Tyr363 phosphorylated form 分子名称: E3 ubiquitin-protein ligase CBL-B, ZINC ION 著者 Kumeta, H, Kobashigawa, Y, Inagaki, F. 登録日 2011-06-01 公開日 2011-12-14 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Autoinhibition and phosphorylation-induced activation mechanisms of human cancer and autoimmune disease-related E3 protein Cbl-b Proc.Natl.Acad.Sci.USA, 108, 2011
2QNZ	Crystal structure of the complex between the mycobacterium beta-ketoacyl-acyl carrier protein synthase III (FABH) and SS-(2-hydroxyethyl)-O-decyl ester carbono(dithioperoxoic) acid 分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 3, BETA-MERCAPTOETHANOL, DECYL FORMATE 著者 Sachdeva, S, Musayev, F, Alhamadsheh, M, Scarsdale, J.N, Wright, H.T, Reynolds, K.A. 登録日 2007-07-19 公開日 2008-05-06 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Separate Entrance and Exit Portals for Ligand Traffic in Mycobacterium tuberculosis FabH Chem.Biol., 15, 2008
2N85	NMR structure of OtTx1a - AMP in DPC micelles 分子名称: Spiderine-1a 著者 Nadezhdin, K, Romanovskaya, D, Sachkova, M, Vassilevski, A, Grishin, E, Kovalchuk, S, Arseniev, A. 登録日 2015-10-05 公開日 2016-10-05 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Modular toxin from the lynx spider Oxyopes takobius: Structure of spiderine domains in solution and membrane-mimicking environment. Protein Sci., 26, 2017
2N8P	Solution Structure of Lacticin Q 分子名称: Lacticin Q 著者 Acedo, J.Z, van Belkum, M.J, Lohans, C.T, Towle, K.M, Miskolzie, M, Vederas, J.C. 登録日 2015-10-22 公開日 2016-02-17 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Nuclear Magnetic Resonance Solution Structures of Lacticin Q and Aureocin A53 Reveal a Structural Motif Conserved among Leaderless Bacteriocins with Broad-Spectrum Activity. Biochemistry, 55, 2016
2NQG	Calpain 1 proteolytic core inactivated by WR18(S,S), an epoxysuccinyl-type inhibitor. 分子名称: 5-AZANYLIDYNE-N-[(2S)-4-ETHOXY-2-HYDROXY-4-OXOBUTANOYL]-L-NORVALYL-L-ARGINYL-L-TRYPTOPHANAMIDE, CALCIUM ION, Calpain-1 catalytic subunit 著者 Cuerrier, D, Davies, P.L, Campbell, R.L, Moldoveanu, T. 登録日 2006-10-31 公開日 2007-01-09 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Development of Calpain-specific Inactivators by Screening of Positional Scanning Epoxide Libraries J.Biol.Chem., 282, 2007
2MTM	NMR structure of RCB-1 peptide 分子名称: Putative uncharacterized protein 著者 Boldbaatar, D, Elseedi, H.R. 登録日 2014-08-21 公開日 2015-09-02 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Synthesis, Structural Characterization, and Bioactivity of the Stable Peptide RCB-1 from Ricinus communis. J Nat Prod, 78, 2015
2QO0	Crystal structure of the complex between the A246F mutant of mycobacterium beta-ketoacyl-acyl carrier protein synthase III (FABH) and 11-(decyldithiocarbonyloxy)-undecanoic acid 分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 3, DECANE-1-THIOL 著者 Sachdeva, S, Musayev, F, Alhamadsheh, M, Scarsdale, J.N, Wright, H.T, Reynolds, K.A. 登録日 2007-07-19 公開日 2008-05-06 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Separate Entrance and Exit Portals for Ligand Traffic in Mycobacterium tuberculosis FabH Chem.Biol., 15, 2008
2N86	NMR structure of OtTx1a - ICK 分子名称: Spiderine-1a 著者 Nadezhdin, K, Romanovskaya, D, Sachkova, M, Vassilevski, A, Grishin, E, Kovalchuk, S, Arseniev, A. 登録日 2015-10-05 公開日 2016-10-19 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Modular toxin from the lynx spider Oxyopes takobius: Structure of spiderine domains in solution and membrane-mimicking environment. Protein Sci., 26, 2017
2N8O	NMR Solution Structure of Aureocin A53 分子名称: Bacteriocin aureocin A53 著者 Acedo, J.Z, van Belkum, M.J, Lohans, C.T, Towle, K.M, Miskolzie, M, Vederas, J.C. 登録日 2015-10-22 公開日 2016-02-17 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Nuclear Magnetic Resonance Solution Structures of Lacticin Q and Aureocin A53 Reveal a Structural Motif Conserved among Leaderless Bacteriocins with Broad-Spectrum Activity. Biochemistry, 55, 2016
2QNX	Crystal structure of the complex between the mycobacterium beta-ketoacyl-acyl carrier protein synthase III (FABH) and 11-[(decyloxycarbonyl)dithio]-undecanoic acid 分子名称: 11-MERCAPTOUNDECANOIC ACID, 3-oxoacyl-[acyl-carrier-protein] synthase 3, O-DECYL HYDROGEN THIOCARBONATE 著者 Sachdeva, S, Musayev, F, Alhamadsheh, M, Scarsdale, J.N, Wright, H.T, Reynolds, K.A. 登録日 2007-07-19 公開日 2008-05-06 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Separate Entrance and Exit Portals for Ligand Traffic in Mycobacterium tuberculosis FabH Chem.Biol., 15, 2008
2LMI	NMR structure of the protein BC040485 from Homo sapiens 分子名称: G-rich sequence factor 1 著者 Dutta, S.K, Serrano, P, Geralt, M, Wuthrich, K, Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL) 登録日 2011-12-01 公開日 2011-12-28 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 NMR structure of the human RNA binding protein BC040485 To be Published
2QO1	2.6 Angstrom Crystal Structure of the Complex Between 11-(decyldithiocarbonyloxy)-undecanoic acid and Mycobacterium Tuberculosis FabH. 分子名称: 11-[(MERCAPTOCARBONYL)OXY]UNDECANOIC ACID, 3-oxoacyl-[acyl-carrier-protein] synthase 3, DECANE-1-THIOL 著者 Sachdeva, S, Musayev, F, Alhamadsheh, M, Scarsdale, J.N, Wright, H.T, Reynolds, K.A. 登録日 2007-07-19 公開日 2008-05-06 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Separate Entrance and Exit Portals for Ligand Traffic in Mycobacterium tuberculosis FabH Chem.Biol., 15, 2008
4CXM	Crystal Structure of Plasmodium Falciparum Spermidine Synthase in Complex with METHYLTHIOADENOSIN AND SPERMIDINE after catalysis in crystal 分子名称: 5'-DEOXY-5'-METHYLTHIOADENOSINE, SPERMIDINE, SPERMIDINE SYNTHASE 著者 Sprenger, J, Svensson, B, Al-Karadaghi, S, Persson, L. 登録日 2014-04-07 公開日 2014-10-08 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Three-Dimensional Structures of Plasmodium Falciparum Spermidine Synthase with Bound Inhibitors Suggest New Strategies for Drug Design. Acta Crystallogr.,Sect.D, 71, 2015
4CWA	Structure of Plasmodium Falciparum Spermidine Synthase in Complex with 1H-Benzimidazole-2-pentanamine 分子名称: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, 5-(1H-benzimidazol-2-yl)pentan-1-amine, SPERMIDINE SYNTHASE 著者 Sprenger, J, Halander, J.C, Svensson, B, Al-Karadaghi, S, Persson, L. 登録日 2014-04-01 公開日 2014-10-08 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Three-Dimensional Structures of Plasmodium Falciparum Spermidine Synthase with Bound Inhibitors Suggest New Strategies for Drug Design. Acta Crystallogr.,Sect.D, 71, 2015
4X49	Crystal structure of the intramolecular trans-sialidase from Ruminococcus gnavus in complex with oseltamivir carboxylate 分子名称: (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, ACETYL GROUP, Anhydrosialidase, ... 著者 Owen, C.D, Tailford, L.E, Taylor, G.L, Juge, N. 登録日 2014-12-02 公開日 2015-07-22 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Discovery of intramolecular trans-sialidases in human gut microbiota suggests novel mechanisms of mucosal adaptation. Nat Commun, 6, 2015
4D7N	TetR(D) in complex with anhydrotetracycline and potassium 分子名称: 5A,6-ANHYDROTETRACYCLINE, CHLORIDE ION, POTASSIUM ION, ... 著者 Werten, S, Dalm, D, Palm, G.J, Hinrichs, W. 登録日 2014-11-25 公開日 2014-12-10 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Tetracycline Repressor Allostery Does not Depend on Divalent Metal Recognition. Biochemistry, 53, 2014
1SR7	Progesterone Receptor Hormone Binding Domain with Bound Mometasone Furoate 分子名称: GLYCEROL, MOMETASONE FUROATE, Progesterone receptor, ... 著者 Madauss, K.P, Deng, S.-J, Austin, R.J, Lambert, M.H, McLay, I, Pritchard, J, Short, S.A, Stewart, E.L, Uings, I.J, Williams, S.P. 登録日 2004-03-22 公開日 2004-06-22 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.46 Å) 主引用文献 Progesterone receptor ligand binding pocket flexibility: crystal structures of the norethindrone and mometasone furoate complexes J.Med.Chem., 47, 2004
4E3L	Crystal structure of AmpC beta-lactamase in complex with a 3-chloro-4-tetrazolyl benzene sulfonamide boronic acid inhibitor 分子名称: Beta-lactamase, PHOSPHATE ION, [({[3-chloro-4-(1H-tetrazol-5-yl)phenyl]sulfonyl}amino)methyl]boronic acid 著者 Eidam, O, Shoichet, B.K. 登録日 2012-03-09 公開日 2012-09-26 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.43 Å) 主引用文献 Fragment-guided design of subnanomolar beta-lactamase inhibitors active in vivo. Proc.Natl.Acad.Sci.USA, 109, 2012
4E3K	Crystal structure of AmpC beta-lactamase in complex with a designed 4-tetrazolyl pyridine sulfonamide boronic acid inhibitor 分子名称: Beta-lactamase, PHOSPHATE ION, [({[6-(1H-tetrazol-5-yl)pyridin-3-yl]sulfonyl}amino)methyl]boronic acid 著者 Eidam, O, Shoichet, B.K. 登録日 2012-03-09 公開日 2012-09-26 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.4299 Å) 主引用文献 Fragment-guided design of subnanomolar beta-lactamase inhibitors active in vivo. Proc.Natl.Acad.Sci.USA, 109, 2012
4E3N	Crystal structure of AmpC beta-lactamase in complex with a 2-trifluoromethyl-4-tetrazolyl benzene sulfonamide boronic acid inhibitor 分子名称: Beta-lactamase, PHOSPHATE ION, [({[4-(1H-tetrazol-5-yl)-2-(trifluoromethyl)phenyl]sulfonyl}amino)methyl]boronic acid 著者 Eidam, O, Shoichet, B.K. 登録日 2012-03-09 公開日 2012-09-26 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Fragment-guided design of subnanomolar beta-lactamase inhibitors active in vivo. Proc.Natl.Acad.Sci.USA, 109, 2012
5EIR	Co-crystal structure of eIF4E with nucleotide mimetic inhibitor. 分子名称: Eukaryotic translation initiation factor 4 gamma 1, Eukaryotic translation initiation factor 4E, SULFATE ION, ... 著者 Nowicki, M.W, Walkinshaw, M.D, Fischer, P.M. 登録日 2015-10-30 公開日 2016-09-07 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 Design of nucleotide-mimetic and non-nucleotide inhibitors of the translation initiation factor eIF4E: Synthesis, structural and functional characterisation. Eur.J.Med.Chem., 124, 2016
8PR0	Cytoplasmic dynein-A heavy chain bound to dynactin-p150glued and IC-LC tower 分子名称: Cytoplasmic dynein 1 heavy chain 1, Cytoplasmic dynein 1 intermediate chain 2, Cytoplasmic dynein 1 light intermediate chain 2, ... 著者 Singh, K, Lau, C.K, Manigrasso, G, Gassmann, R, Carter, A.P. 登録日 2023-07-12 公開日 2024-03-27 最終更新日 2024-04-10 実験手法 ELECTRON MICROSCOPY (9.4 Å) 主引用文献 Molecular mechanism of dynein-dynactin complex assembly by LIS1. Science, 383, 2024

<282283284285286287288289290291292293294295296297>