8PR0

Cytoplasmic dynein-A heavy chain bound to dynactin-p150glued and IC-LC tower

This is a non-PDB format compatible entry.

Summary for 8PR0

• Entry DOI: 10.2210/pdb8pr0/pdb
• EMDB information: 17830
• Descriptor: Cytoplasmic dynein 1 intermediate chain 2, Dynein light chain 1, cytoplasmic, Dynein light chain Tctex-type 1, ... (6 entities in total)
• Functional Keywords: dynein, aaa-atpase, dynactin, p150, lc8, tctex1, motor protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 11
• Total formula weight: 1586886.45

Authors

Singh, K.,Lau, C.K.,Manigrasso, G.,Gassmann, R.,Carter, A.P. (deposition date: 2023-07-12, release date: 2024-03-27, Last modification date: 2024-04-10)

• Primary citation: Singh, K.,Lau, C.K.,Manigrasso, G.,Gama, J.B.,Gassmann, R.,Carter, A.P.; Molecular mechanism of dynein-dynactin complex assembly by LIS1.; Science, 383:eadk8544-eadk8544, 2024; PubMed: 38547289; DOI: 10.1126/science.adk8544

Experimental method

ELECTRON MICROSCOPY (9.4 Å)