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5DND
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BU of 5dnd by Molmil
Crystal structure of the Asn-bound guinea pig L-asparaginase 1 catalytic domain active site mutant T116A
分子名称: 1,2-ETHANEDIOL, ASPARAGINE, L-asparaginase
著者Schalk, A.M, Lavie, A.
登録日2015-09-09
公開日2016-01-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Experimental Data in Support of a Direct Displacement Mechanism for Type I/II l-Asparaginases.
J.Biol.Chem., 291, 2016
7NKF
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BU of 7nkf by Molmil
Hen egg white lysozyme (HEWL) Grown inside (Not centrifuged) HARE serial crystallography chip.
分子名称: Lysozyme, SODIUM ION
著者Norton-Baker, B, Mehrabi, P, Boger, J, Schonherr, R, von Stetten, D, Schikora, H, Martin, R.W, Miller, R.J.D, Redecke, L, Schulz, E.C.
登録日2021-02-17
公開日2021-06-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A simple vapor-diffusion method enables protein crystallization inside the HARE serial crystallography chip.
Acta Crystallogr D Struct Biol, 77, 2021
5DNE
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BU of 5dne by Molmil
Crystal structure of the Asn-bound guinea pig L-asparaginase 1 catalytic domain active site mutant K188M
分子名称: 1,2-ETHANEDIOL, ASPARAGINE, L-asparaginase
著者Schalk, A.M, Lavie, A.
登録日2015-09-10
公開日2016-01-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Experimental Data in Support of a Direct Displacement Mechanism for Type I/II l-Asparaginases.
J.Biol.Chem., 291, 2016
5LP6
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BU of 5lp6 by Molmil
Crystal structure of Tubulin-Stathmin-TTL-Thiocolchicine Complex
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ...
著者Marangon, J, Christodoulou, M, Casagrande, F, Tiana, G, Dalla Via, L, Aliverti, A, Passarella, D, Cappelletti, G, Ricagno, S.
登録日2016-08-11
公開日2016-09-21
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Tools for the rational design of bivalent microtubule-targeting drugs.
Biochem. Biophys. Res. Commun., 479, 2016
7S7P
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BU of 7s7p by Molmil
NMR solution structure of a neurotoxic thionin from Urtica ferox
分子名称: urthionin-Uf1a
著者Durek, T, Harvey, P.J, Craik, D.J.
登録日2021-09-16
公開日2022-07-27
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Neurotoxic and cytotoxic peptides underlie the painful stings of the tree nettle Urtica ferox.
J.Biol.Chem., 298, 2022
8PFJ
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BU of 8pfj by Molmil
fully recruited RfaH bound to E. coli transcription complex paused at ops site (not fully complementary scaffold; alternative state of RfaH)
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H.
登録日2023-06-16
公開日2024-04-24
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Concerted transformation of a hyper-paused transcription complex and its reinforcing protein.
Nat Commun, 15, 2024
5E6E
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BU of 5e6e by Molmil
Crystal Structure of Carbonmonoxy Sickle Hemoglobin in R-State Conformation
分子名称: CARBON MONOXIDE, Hemoglobin subunit alpha, Hemoglobin subunit beta, ...
著者Safo, M.K, Ahmed, M.H.
登録日2015-10-09
公開日2015-10-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Crystal structure of carbonmonoxy sickle hemoglobin in R-state conformation.
J.Struct.Biol., 194, 2016
6BSN
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BU of 6bsn by Molmil
Structure of proline utilization A (PutA) with proline bound in remote sites
分子名称: Bifunctional protein PutA, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, PROLINE, ...
著者Tanner, J.J, Korasick, D.A.
登録日2017-12-04
公開日2018-01-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural Basis for the Substrate Inhibition of Proline Utilization A by Proline.
Molecules, 23, 2017
5HI8
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BU of 5hi8 by Molmil
Structure of T-type Phycobiliprotein Lyase CpeT from Prochlorococcus phage P-HM1
分子名称: ACETATE ION, Antenna protein, MAGNESIUM ION
著者Gasper, R, Schwach, J, Frankenberg-Dinkel, N, Hofmann, E.
登録日2016-01-11
公開日2017-01-18
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Distinct Features of Cyanophage-encoded T-type Phycobiliprotein Lyase Phi CpeT: THE ROLE OF AUXILIARY METABOLIC GENES.
J. Biol. Chem., 292, 2017
5DNC
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BU of 5dnc by Molmil
Crystal structure of the Asn-bound guinea pig L-asparaginase 1 catalytic domain active site mutant T19A
分子名称: 1,2-ETHANEDIOL, ASPARAGINE, L-asparaginase
著者Schalk, A.M, Lavie, A.
登録日2015-09-09
公開日2016-01-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Experimental Data in Support of a Direct Displacement Mechanism for Type I/II l-Asparaginases.
J.Biol.Chem., 291, 2016
6BTV
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BU of 6btv by Molmil
Solution NMR structures for CcoTx-II
分子名称: Beta-theraphotoxin-Cm1b
著者Agwa, A.J, Schroeder, C.I.
登録日2017-12-07
公開日2018-05-09
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Gating modifier toxins isolated from spider venom: Modulation of voltage-gated sodium channels and the role of lipid membranes.
J. Biol. Chem., 293, 2018
6BR0
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BU of 6br0 by Molmil
Solution NMR structure for CcoTx-I
分子名称: Beta-theraphotoxin-Cm1a
著者Agwa, A.J, Schroeder, C.I.
登録日2017-11-29
公開日2018-05-16
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Gating modifier toxins isolated from spider venom: Modulation of voltage-gated sodium channels and the role of lipid membranes.
J. Biol. Chem., 293, 2018
5TMN
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BU of 5tmn by Molmil
Slow-and fast-binding inhibitors of thermolysin display different modes of binding. crystallographic analysis of extended phosphonamidate transition-state analogues
分子名称: CALCIUM ION, N-[(S)-({[(benzyloxy)carbonyl]amino}methyl)(hydroxy)phosphoryl]-L-leucyl-L-leucine, THERMOLYSIN, ...
著者Holden, H.M, Tronrud, D.E, Monzingo, A.F, Weaver, L.H, Matthews, B.W.
登録日1987-06-29
公開日1989-01-09
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Slow- and fast-binding inhibitors of thermolysin display different modes of binding: crystallographic analysis of extended phosphonamidate transition-state analogues.
Biochemistry, 26, 1987
5UFU
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BU of 5ufu by Molmil
Structure of AMPK bound to activator
分子名称: 1,4:3,6-dianhydro-2-O-(6-chloro-5-{4-[1-(hydroxymethyl)cyclopropyl]phenyl}-1H-benzimidazol-2-yl)-D-mannitol, 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-1, ...
著者Calabrese, M.F, Kurumbail, R.G.
登録日2017-01-05
公開日2017-05-17
実験手法X-RAY DIFFRACTION (3.45 Å)
主引用文献Activation of Skeletal Muscle AMPK Promotes Glucose Disposal and Glucose Lowering in Non-human Primates and Mice.
Cell Metab., 25, 2017
8UDZ
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BU of 8udz by Molmil
The Structure of LTBP-49247 Fab Bound to TGFbeta1 Small Latent Complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, LTBP-49247 Fab Heavy Chain, LTBP-49247 Fab Light Chain, ...
著者Streich Jr, F.C, Nicholls, S.B, Boston, C.J, Ramachandran, S.
登録日2023-09-29
公開日2024-07-17
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献An antibody that inhibits TGF-beta 1 release from latent extracellular matrix complexes attenuates the progression of renal fibrosis.
Sci.Signal., 17, 2024
5TSS
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BU of 5tss by Molmil
TOXIC SHOCK SYNDROME TOXIN-1: ORTHORHOMBIC P222(1) CRYSTAL FORM
分子名称: TOXIC SHOCK SYNDROME TOXIN-1
著者Prasad, G.S, Radhakrishnan, R, Mitchell, D.T, Earhart, C.A, Dinges, M.M, Cook, W.J, Schlivert, P.M, Ohlendorf, D.H.
登録日1996-12-11
公開日1997-12-24
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Refined structures of three crystal forms of toxic shock syndrome toxin-1 and of a tetramutant with reduced activity.
Protein Sci., 6, 1997
6KAV
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BU of 6kav by Molmil
Carbonmonoxy human hemoglobin A in the R2 quaternary structure at 140 K: Light
分子名称: CARBON MONOXIDE, Hemoglobin subunit alpha, Hemoglobin subunit beta, ...
著者Shibayama, N, Park, S.Y, Ohki, M, Sato-Tomita, A.
登録日2019-06-24
公開日2020-02-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Direct observation of ligand migration within human hemoglobin at work.
Proc.Natl.Acad.Sci.USA, 117, 2020
8AAV
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BU of 8aav by Molmil
Human heavy chain ferritin with introduced Cys residues modified with C10 ligand
分子名称: 2-bromanyl-N-decyl-ethanamide, FE (III) ION, Ferritin heavy chain, ...
著者Boehler, H, Beck, T.
登録日2022-07-03
公開日2024-03-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Assembly of chemically modified protein nanocages into 3D materials for the adsorption of uremic toxins.
J Mater Chem B, 11, 2022
5V7D
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BU of 5v7d by Molmil
T4 lysozyme Y18Ymbr
分子名称: 2-HYDROXYETHYL DISULFIDE, Lysozyme
著者Carlsson, A.-C.C.
登録日2017-03-20
公開日2018-06-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Increasing Enzyme Stability and Activity through Hydrogen Bond-Enhanced Halogen Bonds.
Biochemistry, 57, 2018
6JUO
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BU of 6juo by Molmil
MsDpo4-DNA complex 4
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(P*CP*TP*GP*GP*GP*GP*TP*CP*CP*TP*AP*GP*G)-3'), DNA polymerase IV, ...
著者Nair, D.T, Johnson, M.K.
登録日2019-04-15
公開日2020-02-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献A polar filter in DNA polymerases prevents ribonucleotide incorporation.
Nucleic Acids Res., 47, 2019
6KAP
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BU of 6kap by Molmil
Carbonmonoxy human hemoglobin C in the R quaternary structure at 95 K: Light
分子名称: CARBON MONOXIDE, Hemoglobin subunit alpha, Hemoglobin subunit beta, ...
著者Shibayama, N, Park, S.Y, Ohki, M, Sato-Tomita, A.
登録日2019-06-23
公開日2020-02-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Direct observation of ligand migration within human hemoglobin at work.
Proc.Natl.Acad.Sci.USA, 117, 2020
6KAT
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BU of 6kat by Molmil
Carbonmonoxy human hemoglobin A in the R2 quaternary structure at 95 K: Light
分子名称: CARBON MONOXIDE, Hemoglobin subunit alpha, Hemoglobin subunit beta, ...
著者Shibayama, N, Park, S.Y, Ohki, M, Sato-Tomita, A.
登録日2019-06-24
公開日2020-02-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Direct observation of ligand migration within human hemoglobin at work.
Proc.Natl.Acad.Sci.USA, 117, 2020
6KAI
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BU of 6kai by Molmil
Crosslinked alpha(Ni)-beta(Fe) human hemoglobin A in the T quaternary structure at 95 K: Light
分子名称: BUT-2-ENEDIAL, CARBON MONOXIDE, Hemoglobin subunit alpha, ...
著者Shibayama, N, Park, S.Y, Ohki, M, Sato-Tomita, A.
登録日2019-06-23
公開日2020-02-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Direct observation of ligand migration within human hemoglobin at work.
Proc.Natl.Acad.Sci.USA, 117, 2020
6KAS
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BU of 6kas by Molmil
Carbonmonoxy human hemoglobin A in the R2 quaternary structure at 95 K: Dark
分子名称: CARBON MONOXIDE, Hemoglobin subunit alpha, Hemoglobin subunit beta, ...
著者Shibayama, N, Park, S.Y, Ohki, M, Sato-Tomita, A.
登録日2019-06-24
公開日2020-02-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Direct observation of ligand migration within human hemoglobin at work.
Proc.Natl.Acad.Sci.USA, 117, 2020
5SWQ
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BU of 5swq by Molmil
Crystal Structure of HLA-A*0201 in complex with NA231, an influenza epitope
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
著者Josephs, T.M, Rossjohn, J, Gras, S.
登録日2016-08-08
公開日2016-10-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Lack of Heterologous Cross-reactivity toward HLA-A*02:01 Restricted Viral Epitopes Is Underpinned by Distinct alpha beta T Cell Receptor Signatures.
J.Biol.Chem., 291, 2016

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