6QD3
 
 | | MloK1 model from single particle analysis of 2D crystals, class 7 (intermediate conformation) | | 分子名称: | Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION | | 著者 | Righetto, R, Biyani, N, Kowal, J, Chami, M, Stahlberg, H. | | 登録日 | 2018-12-31 | | 公開日 | 2019-04-24 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (5 Å) | | 主引用文献 | Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM.
Nat Commun, 10, 2019
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1VWC
 | | STREPTAVIDIN-CYCLO-AC-[CHPQFC]-NH2, PH 2.0 | | 分子名称: | PEPTIDE LIGAND CONTAINING HPQ, STREPTAVIDIN | | 著者 | Katz, B.A, Cass, R.T. | | 登録日 | 1997-03-03 | | 公開日 | 1998-03-18 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | In crystals of complexes of streptavidin with peptide ligands containing the HPQ sequence the pKa of the peptide histidine is less than 3.0.
J.Biol.Chem., 272, 1997
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2FX8
 | | Crystal structure of hiv-1 neutralizing human fab 4e10 in complex with an aib-induced peptide encompassing the 4e10 epitope on gp41 | | 分子名称: | Fab 4E10, Fragment of HIV glycoprotein (GP41) | | 著者 | Cardoso, R.M.F, Brunel, F.M, Ferguson, S, Burton, D.R, Dawson, P.E, Wilson, I.A. | | 登録日 | 2006-02-03 | | 公開日 | 2006-12-19 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural basis of enhanced binding of extended and helically constrained peptide epitopes of the broadly neutralizing HIV-1 antibody 4E10.
J.Mol.Biol., 365, 2007
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6QF6
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6D9Q
 | | The sulfate-bound crystal structure of HPRT (hypoxanthine phosphoribosyltransferase) | | 分子名称: | GLYCEROL, Hypoxanthine phosphoribosyltransferase, SULFATE ION | | 著者 | Satyshur, K.A, Dubiel, K, Anderson, B, Wolak, C, Keck, J.L. | | 登録日 | 2018-04-30 | | 公開日 | 2019-05-01 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.056 Å) | | 主引用文献 | Evolution of (p)ppGpp-HPRT regulation through diversification of an allosteric oligomeric interaction.
Elife, 8, 2019
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6QJ5
 | | X-ray structure of PPARgamma LBD with the ligand NV1380 | | 分子名称: | (2~{S})-3-methyl-2-[(4-octoxyphenyl)carbonylamino]butanoic acid, Peroxisome proliferator-activated receptor gamma | | 著者 | Pochetti, G, Montanari, R, Capelli, D. | | 登録日 | 2019-01-22 | | 公開日 | 2020-02-05 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A Novel N-Substituted Valine Derivative with Unique Peroxisome Proliferator-Activated Receptor gamma Binding Properties and Biological Activities.
J.Med.Chem., 63, 2020
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6QJX
 | | TetR(D) T103A mutant in complex with minocycline and magnesium | | 分子名称: | (4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2- CARBOXAMIDE, CHLORIDE ION, MAGNESIUM ION, ... | | 著者 | Hinrichs, W, Palm, G.J, Berndt, L, Girbardt, B. | | 登録日 | 2019-01-27 | | 公開日 | 2019-08-21 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Thermodynamics, cooperativity and stability of the tetracycline repressor (TetR) upon tetracycline binding.
Biochim Biophys Acta Proteins Proteom, 1868, 2020
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1VWD
 | | STREPTAVIDIN-CYCLO-AC-[CHPQFC]-NH2, PH 3.0 | | 分子名称: | PEPTIDE LIGAND CONTAINING HPQ, STREPTAVIDIN | | 著者 | Katz, B.A, Cass, R.T. | | 登録日 | 1997-03-03 | | 公開日 | 1998-03-18 | | 最終更新日 | 2011-11-16 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | In crystals of complexes of streptavidin with peptide ligands containing the HPQ sequence the pKa of the peptide histidine is less than 3.0.
J.Biol.Chem., 272, 1997
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6QK8
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4NXB
 | | Crystal structure of iLOV-I486(2LT) at pH 7.0 | | 分子名称: | FLAVIN MONONUCLEOTIDE, Phototropin-2 | | 著者 | Wang, J, Li, J, Liu, X. | | 登録日 | 2013-12-09 | | 公開日 | 2014-09-24 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.561 Å) | | 主引用文献 | Significant expansion of fluorescent protein sensing ability through the genetic incorporation of superior photo-induced electron-transfer quenchers.
J.Am.Chem.Soc., 136, 2014
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6DBQ
 | | Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs | | 分子名称: | CALCIUM ION, Molecule name: Forward strand of 12-RSS substrate DNA, Molecule name: Forward strand of 23-RSS substrate DNA, ... | | 著者 | Wu, H, Liao, M, Ru, H, Mi, W. | | 登録日 | 2018-05-03 | | 公開日 | 2018-08-01 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4.22 Å) | | 主引用文献 | DNA melting initiates the RAG catalytic pathway.
Nat. Struct. Mol. Biol., 25, 2018
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6QHT
 | | Time resolved structural analysis of the full turnover of an enzyme - 376 ms | | 分子名称: | Fluoroacetate dehalogenase, fluoroacetic acid | | 著者 | Schulz, E.C, Mehrabi, P, Pai, E.F, Miller, D. | | 登録日 | 2019-01-17 | | 公開日 | 2019-09-25 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Time-resolved crystallography reveals allosteric communication aligned with molecular breathing.
Science, 365, 2019
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6QI2
 | | Time resolved structural analysis of the full turnover of an enzyme - 13536 ms | | 分子名称: | Fluoroacetate dehalogenase, GLYCOLIC ACID | | 著者 | Schulz, E.C, Mehrabi, P, Pai, E.F, Miller, D. | | 登録日 | 2019-01-17 | | 公開日 | 2019-09-25 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Time-resolved crystallography reveals allosteric communication aligned with molecular breathing.
Science, 365, 2019
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6D8X
 | | PPAR gamma LBD complexed with the agonist GW1929 | | 分子名称: | (2~{S})-3-[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]-2-[[2-(phenylcarbonyl)phenyl]amino]propanoic acid, CITRATE ANION, GLYCEROL, ... | | 著者 | Mou, T.C, Chrisman, I.M, Hughes, T.S, Sprang, S.R. | | 登録日 | 2018-04-27 | | 公開日 | 2019-05-01 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | PPAR gamma LBD complexed with the agonist GW1929
To Be Published
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6QII
 | | Xenon derivatization of the F420-reducing [NiFe] hydrogenase complex from Methanosarcina barkeri | | 分子名称: | (R,R)-2,3-BUTANEDIOL, Coenzyme F420 hydrogenase subunit alpha, Coenzyme F420 hydrogenase subunit beta, ... | | 著者 | Ilina, Y, Lorent, C, Katz, S, Jeoung, J.H, Shima, S, Horch, M, Zebger, I, Dobbek, H. | | 登録日 | 2019-01-19 | | 公開日 | 2019-10-23 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | X-ray Crystallography and Vibrational Spectroscopy Reveal the Key Determinants of Biocatalytic Dihydrogen Cycling by [NiFe] Hydrogenases.
Angew.Chem.Int.Ed.Engl., 58, 2019
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6DCZ
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6DBW
 | | Cryo-EM structure of RAG in complex with 12-RSS substrate DNA | | 分子名称: | CALCIUM ION, Forward strand of 12-RSS substrate DNA, Recombination activating gene 1 - MBP chimera, ... | | 著者 | Wu, H, Liao, M, Ru, H, Mi, W. | | 登録日 | 2018-05-03 | | 公開日 | 2018-08-01 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | | 主引用文献 | DNA melting initiates the RAG catalytic pathway.
Nat. Struct. Mol. Biol., 25, 2018
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6QKW
 | | Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - Tyr219Phe - Fluoroacetate soaked 2hr | | 分子名称: | CHLORIDE ION, Fluoroacetate dehalogenase, GLYCOLIC ACID, ... | | 著者 | Mehrabi, P, Kim, T.H, Prosser, R.S, Pai, E.F. | | 登録日 | 2019-01-30 | | 公開日 | 2019-06-26 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.512 Å) | | 主引用文献 | Substrate-Based Allosteric Regulation of a Homodimeric Enzyme.
J.Am.Chem.Soc., 141, 2019
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6DCM
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6QLD
 | | Structure of inner kinetochore CCAN-Cenp-A complex | | 分子名称: | DNA (125-MER), Histone H2A.1, Histone H2B.1, ... | | 著者 | Yan, K, Yang, J, Zhang, Z, McLaughlin, S.H, Chang, L, Fasci, D, Heck, A.J.R, Barford, D. | | 登録日 | 2019-01-31 | | 公開日 | 2019-10-02 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4.15 Å) | | 主引用文献 | Structure of the inner kinetochore CCAN complex assembled onto a centromeric nucleosome.
Nature, 574, 2019
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6Q9A
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1W8K
 | | Crystal structure of apical membrane antigen 1 from Plasmodium vivax | | 分子名称: | APICAL MEMBRANE ANTIGEN 1, IMIDAZOLE | | 著者 | Pizarro, J.C, Vulliez-Le Normand, B, Chesne-Seck, M.-L, Kocken, C.H.M, Thomas, A.W, Bentley, G.A. | | 登録日 | 2004-09-23 | | 公開日 | 2005-03-01 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal Structure of the Malaria Vaccine Candidate Apical Membrane Antigen 1
Science, 308, 2005
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6DF1
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6DFA
 | | Kaiso (ZBTB33) E535A zinc finger DNA binding domain in complex with the specific Kaiso binding sequence (KBS) | | 分子名称: | CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*GP*GP*CP*AP*GP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*CP*TP*GP*CP*CP*AP*AP*TP*AP*AP*CP*G)-3'), ... | | 著者 | Nikolova, E.N, Stanfield, R.L, Dyson, H.J, Wright, P.E. | | 登録日 | 2018-05-14 | | 公開日 | 2019-05-22 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.908 Å) | | 主引用文献 | A conformational switch in the zinc finger protein Kaiso mediates differential readout of specific and methylated DNA sequences.
Biochemistry, 2020
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3GKE
 | | Crystal Structure of Dicamba Monooxygenase | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, DdmC, ... | | 著者 | Wilson, M.A, Dumitru, R, Jiang, W.Z, Weeks, D.P. | | 登録日 | 2009-03-10 | | 公開日 | 2009-07-21 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Crystal structure of dicamba monooxygenase: a Rieske nonheme oxygenase that catalyzes oxidative demethylation.
J.Mol.Biol., 392, 2009
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