6QJX
TetR(D) T103A mutant in complex with minocycline and magnesium
Summary for 6QJX
Entry DOI | 10.2210/pdb6qjx/pdb |
Descriptor | Tetracycline repressor protein class D, (4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2- CARBOXAMIDE, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | transcription regulation, transcription |
Biological source | Escherichia coli |
Total number of polymer chains | 1 |
Total formula weight | 23881.90 |
Authors | Hinrichs, W.,Palm, G.J.,Berndt, L.,Girbardt, B. (deposition date: 2019-01-27, release date: 2019-08-21, Last modification date: 2024-01-24) |
Primary citation | Palm, G.J.,Buchholz, I.,Werten, S.,Girbardt, B.,Berndt, L.,Delcea, M.,Hinrichs, W. Thermodynamics, cooperativity and stability of the tetracycline repressor (TetR) upon tetracycline binding. Biochim Biophys Acta Proteins Proteom, 1868:140404-140404, 2020 Cited by PubMed: 32114262DOI: 10.1016/j.bbapap.2020.140404 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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