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6QJX

TetR(D) T103A mutant in complex with minocycline and magnesium

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ATetracycline repressor protein class Dpolymer20723258.31UniProt (P0ACT4)
Pfam (PF00440)
Pfam (PF02909)
In PDB
Escherichia coli
2A(4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2- CARBOXAMIDEnon-polymer457.51Chemie (MIY)
3AMAGNESIUM IONnon-polymer24.31Chemie (MG)
4ACHLORIDE IONnon-polymer35.54Chemie (CL)
5waterwater18.041Chemie (HOH)
Sequence modifications
A: 2 - 208 (UniProt: P0ACT4)
PDBExternal DatabaseDetails
Ser 2Ala 2engineered mutation
Ala 103Thr 103engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight23258.3
Non-Polymers*Number of molecules6
Total formula weight623.6
All*Total formula weight23881.9
*Water molecules are not included.

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PDB entries from 2024-07-17

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