2LI0
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![BU of 2li0 by Molmil](/molmil-images/mine/2li0) | Mono-O-GalNAc glycosylated Mucin sequence based on MUC2 Mucin glycoprotein tandem repeat | 分子名称: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, MUC2 Mucin Domain Peptide | 著者 | Borgert, A, Heimburg-Molinaro, J, Lasanajak, Y, Ju, T, Liu, M, Thompson, P, Ragupathi, G, Barany, G, Cummings, R, Smith, D, Live, D. | 登録日 | 2011-08-18 | 公開日 | 2012-04-04 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Deciphering structural elements of mucin glycoprotein recognition. Acs Chem.Biol., 7, 2012
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2LHW
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![BU of 2lhw by Molmil](/molmil-images/mine/2lhw) | Tri-O-GalNAc glycosylated Mucin sequence based on MUC2 Mucin glycoprotein tandem repeat | 分子名称: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, MUC2 Mucin Domain Peptide | 著者 | Borgert, A, Heimburg-Molinaro, J, Lasanajak, Y, Ju, T, Liu, M, Thompson, P, Ragupathi, G, Barany, G, Cummings, R, Smith, D, Live, D. | 登録日 | 2011-08-18 | 公開日 | 2012-04-04 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Deciphering structural elements of mucin glycoprotein recognition. Acs Chem.Biol., 7, 2012
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2LI2
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![BU of 2li2 by Molmil](/molmil-images/mine/2li2) | Mono-O-GalNAc glycosylated Mucin sequence based on MUC2 Mucin glycoprotein tandem repeat | 分子名称: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, MUC2 Mucin Domain Peptide | 著者 | Borgert, A, Heimburg-Molinaro, J, Lasanajak, Y, Ju, T, Liu, M, Thompson, P, Ragupathi, G, Barany, G, Cummings, R, Smith, D, Live, D. | 登録日 | 2011-08-18 | 公開日 | 2012-04-04 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Deciphering structural elements of mucin glycoprotein recognition. Acs Chem.Biol., 7, 2012
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7QUV
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![BU of 7quv by Molmil](/molmil-images/mine/7quv) | Crystal structure of human Calprotectin (S100A8/S100A9) in complex with Peptide 3 | 分子名称: | 1,2-ETHANEDIOL, 4-methanoyl-2-(6-oxidanyl-3-oxidanylidene-4~{H}-xanthen-9-yl)benzoic acid, AMINO GROUP, ... | 著者 | Diaz-Perlas, C, Heinis, C, Pojer, F, Lau, K. | 登録日 | 2022-01-19 | 公開日 | 2023-02-01 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | High-affinity peptides developed against calprotectin and their application as synthetic ligands in diagnostic assays. Nat Commun, 14, 2023
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8C6D
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![BU of 8c6d by Molmil](/molmil-images/mine/8c6d) | Production of antigenically stable enterovirus A71 virus-like particles in Pichia pastoris as a vaccine candidate. | 分子名称: | (2S,3R,4E)-2-aminooctadec-4-ene-1,3-diol, Genome polyprotein, Genome polyprotein (Fragment) | 著者 | Kingston, N.J, Snowden, J.S, Stonehouse, N.J, Rowlands, D.J, Hogle, J.M. | 登録日 | 2023-01-11 | 公開日 | 2023-02-22 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Production of antigenically stable enterovirus A71 virus-like particles in Pichia pastoris as a vaccine candidate. Biorxiv, 2023
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7U8C
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![BU of 7u8c by Molmil](/molmil-images/mine/7u8c) | Crystal structure of Mesothelin C-terminal peptide-MORAb 15B6 FAB complex | 分子名称: | MORab 15B6 Fab heavy chain, MORab 15B6 Fab light chain, Mesothelin, ... | 著者 | Zhan, J, Esser, L, Xia, D. | 登録日 | 2022-03-08 | 公開日 | 2022-06-08 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Highly active CAR T cells that bind to a juxtamembrane region of mesothelin and are not blocked by shed mesothelin. Proc.Natl.Acad.Sci.USA, 119, 2022
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2LHZ
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![BU of 2lhz by Molmil](/molmil-images/mine/2lhz) | Di-O-GalNAc glycosylated Mucin sequence based on MUC2 Mucin glycoprotein tandem repeat | 分子名称: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, MUC2 Mucin Domain Peptide | 著者 | Borgert, A, Heimburg-Molinaro, J, Lasanajak, Y, Ju, T, Liu, M, Thompson, P, Ragupathi, G, Barany, G, Cummings, R, Smith, D, Live, D. | 登録日 | 2011-08-18 | 公開日 | 2012-04-04 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Deciphering structural elements of mucin glycoprotein recognition. Acs Chem.Biol., 7, 2012
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2LHY
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![BU of 2lhy by Molmil](/molmil-images/mine/2lhy) | Di-O-GalNAc glycosylated Mucin sequence based on MUC2 Mucin glycoprotein tandem repeat | 分子名称: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, MUC2 Mucin Domain Peptide | 著者 | Borgert, A, Heimburg-Molinaro, J, Lasanajak, Y, Ju, T, Liu, M, Thompson, P, Ragupathi, G, Barany, G, Cummings, R, Smith, D, Live, D. | 登録日 | 2011-08-18 | 公開日 | 2012-04-04 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Deciphering structural elements of mucin glycoprotein recognition. Acs Chem.Biol., 7, 2012
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2LI1
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![BU of 2li1 by Molmil](/molmil-images/mine/2li1) | Mono-O-GalNAc glycosylated Mucin sequence based on MUC2 Mucin glycoprotein tandem repeat | 分子名称: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, MUC2 Mucin Domain Peptide | 著者 | Borgert, A, Heimburg-Molinaro, J, Lasanajak, Y, Ju, T, Liu, M, Thompson, P, Ragupathi, G, Barany, G, Cummings, R, Smith, D, Live, D. | 登録日 | 2011-08-18 | 公開日 | 2012-04-04 | 最終更新日 | 2020-07-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Deciphering structural elements of mucin glycoprotein recognition. Acs Chem.Biol., 7, 2012
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2LHX
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![BU of 2lhx by Molmil](/molmil-images/mine/2lhx) | Di-O-GalNAc glycosylated Mucin sequence based on MUC2 Mucin glycoprotein tandem repeat | 分子名称: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, MUC2 Mucin Domain Peptide | 著者 | Borgert, A, Heimburg-Molinaro, J, Lasanajak, Y, Ju, T, Liu, M, Thompson, P, Ragupathi, G, Barany, G, Cummings, R, Smith, D, Live, D. | 登録日 | 2011-08-18 | 公開日 | 2012-04-04 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Deciphering structural elements of mucin glycoprotein recognition. Acs Chem.Biol., 7, 2012
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3WHE
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![BU of 3whe by Molmil](/molmil-images/mine/3whe) | A new conserved neutralizing epitope at the globular head of hemagglutinin in H3N2 influenza viruses | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Fujii, Y, Sumida, T, Shirouzu, M, Yokoyama, S. | 登録日 | 2013-08-25 | 公開日 | 2014-04-23 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (4 Å) | 主引用文献 | Conserved neutralizing epitope at globular head of hemagglutinin in H3N2 influenza viruses. J.Virol., 88, 2014
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2W80
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![BU of 2w80 by Molmil](/molmil-images/mine/2w80) | Structure of a complex between Neisseria meningitidis factor H binding protein and CCPs 6-7 of human complement factor H | 分子名称: | COMPLEMENT FACTOR H, FACTOR H BINDING PROTEIN | 著者 | Schneider, M.C, Prosser, B.E, Caesar, J.J.E, Kugelberg, E, Li, S, Zhang, Q, Quoraishi, S, Lovett, J.E, Deane, J.E, Sim, R.B, Roversi, P, Johnson, S, Tang, C.M, Lea, S.M. | 登録日 | 2009-01-08 | 公開日 | 2009-03-03 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Neisseria Meningitidis Recruits Factor H Using Protein Mimicry of Host Carbohydrates. Nature, 458, 2009
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2W5G
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![BU of 2w5g by Molmil](/molmil-images/mine/2w5g) | RNASE A-5'-ATP COMPLEX | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, RIBONUCLEASE PANCREATIC | 著者 | Chavali, G.B, Holloway, D.E, Baker, M.D, Acharya, K.R. | 登録日 | 2008-12-10 | 公開日 | 2009-02-17 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Influence of Naturally-Occurring 5'-Pyrophosphate- Linked Substituents on the Binding of Adenylic Inhibitors to Ribonuclease A: An X-Ray Crystallographic Study. Biopolymers, 91, 2009
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6I07
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![BU of 6i07 by Molmil](/molmil-images/mine/6i07) | Crystal structure of EpCAM in complex with scFv | 分子名称: | Epithelial cell adhesion molecule, GLYCEROL, Single chain Fv | 著者 | Casaletto, J.B, Geddie, M.L, Abu-Yousif, A.O, Masson, K, Fulgham, A, Boudot, A, Maiwald, T, Kearns, J.D, Kohli, N, Su, S, Razlog, M, Raue, A, Kalra, A, Hakansson, M, Logan, D.T, Welin, M, Chattopadhyay, S, Harms, B.D, Nielsen, U.B, Schoeberl, B, Lugovskoy, A.A, MacBeath, G. | 登録日 | 2018-10-25 | 公開日 | 2019-03-13 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | MM-131, a bispecific anti-Met/EpCAM mAb, inhibits HGF-dependent and HGF-independent Met signaling through concurrent binding to EpCAM. Proc.Natl.Acad.Sci.USA, 116, 2019
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6I04
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![BU of 6i04 by Molmil](/molmil-images/mine/6i04) | Crystal structure of Sema domain of the Met receptor in complex with FAB | 分子名称: | Fab heavy chain, Fab light chain, Hepatocyte growth factor receptor | 著者 | Casaletto, J.B, Geddie, M.L, Abu-Yousif, A.O, Masson, K, Fulgham, A, Boudot, A, Maiwald, T, Kearns, J.D, Kohli, N, Su, S, Razlog, M, Raue, A, Kalra, A, Hakansson, M, Logan, D.T, Welin, M, Chattopadhyay, S, Harms, B.D, Nielsen, U.B, Schoeberl, B, Lugovskoy, A.A, MacBeath, G. | 登録日 | 2018-10-25 | 公開日 | 2019-03-13 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | MM-131, a bispecific anti-Met/EpCAM mAb, inhibits HGF-dependent and HGF-independent Met signaling through concurrent binding to EpCAM. Proc.Natl.Acad.Sci.USA, 116, 2019
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6HYG
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![BU of 6hyg by Molmil](/molmil-images/mine/6hyg) | Heteromeric tandem IgG4/IgG1 Fc | 分子名称: | IgHG1 and IgHG4 hybrid, ZINC ION | 著者 | Casaletto, J.B, Geddie, M.L, Abu-Yousif, A.O, Masson, K, Fulgham, A, Boudot, A, Maiwald, T, Kearns, J.D, Kohli, N, Su, S, Razlog, M, Raue, A, Kalra, A, Hakansson, M, Logan, D.T, Welin, M, Chattopadhyay, S, Harms, B.D, Nielsen, U.B, Schoeberl, B, Lugovskoy, A.A, MacBeath, G. | 登録日 | 2018-10-21 | 公開日 | 2019-03-13 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | MM-131, a bispecific anti-Met/EpCAM mAb, inhibits HGF-dependent and HGF-independent Met signaling through concurrent binding to EpCAM. Proc.Natl.Acad.Sci.USA, 116, 2019
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8BPG
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![BU of 8bpg by Molmil](/molmil-images/mine/8bpg) | FcMR binding at subunit Fcu3 of IgM pentamer | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fas apoptotic inhibitory molecule 3, ... | 著者 | Chen, Q, Rosenthal, P, Tolar, P. | 登録日 | 2022-11-16 | 公開日 | 2023-04-12 | 最終更新日 | 2023-07-26 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis for Fc receptor recognition of immunoglobulin M. Nat.Struct.Mol.Biol., 30, 2023
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8BPF
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![BU of 8bpf by Molmil](/molmil-images/mine/8bpf) | FcMR binding at subunit Fcu1 of IgM pentamer | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fas apoptotic inhibitory molecule 3, ... | 著者 | Chen, Q, Rosenthal, P, Tolar, P. | 登録日 | 2022-11-16 | 公開日 | 2023-04-12 | 最終更新日 | 2023-07-26 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural basis for Fc receptor recognition of immunoglobulin M. Nat.Struct.Mol.Biol., 30, 2023
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8BPE
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![BU of 8bpe by Molmil](/molmil-images/mine/8bpe) | 8:1 binding of FcMR on IgM pentameric core | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fas apoptotic inhibitory molecule 3, ... | 著者 | Chen, Q, Rosenthal, P, Tolar, P. | 登録日 | 2022-11-16 | 公開日 | 2023-04-12 | 最終更新日 | 2023-07-26 | 実験手法 | ELECTRON MICROSCOPY (3.63 Å) | 主引用文献 | Structural basis for Fc receptor recognition of immunoglobulin M. Nat.Struct.Mol.Biol., 30, 2023
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8DFL
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![BU of 8dfl by Molmil](/molmil-images/mine/8dfl) | |
7TLT
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![BU of 7tlt by Molmil](/molmil-images/mine/7tlt) | SARS-CoV-2 Spike-derived peptide S489-497 (YFPLQSYGF) presented by HLA-A*29:02 | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A alpha chain, ... | 著者 | Murdolo, L.D, Szeto, C, Gras, S. | 登録日 | 2022-01-18 | 公開日 | 2022-10-12 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Ablation of CD8 + T cell recognition of an immunodominant epitope in SARS-CoV-2 Omicron variants BA.1, BA.2 and BA.3. Nat Commun, 13, 2022
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6V4T
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![BU of 6v4t by Molmil](/molmil-images/mine/6v4t) | MPER-TMD of HIV-1 Env bound with the entry inhibitor S2C3 | 分子名称: | 4,4'-(decane-1,10-diyl)bis(9-amino-2,3-dihydro-1H-cyclopenta[b]quinolin-4-ium), Envelope glycoprotein gp160 | 著者 | Xiao, T, Frey, G, Fu, Q, Lavine, C.L, Scott, D.A, Seaman, M.S, Chou, J.J, Chen, B. | 登録日 | 2019-11-30 | 公開日 | 2020-04-01 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | HIV-1 fusion inhibitors targeting the membrane-proximal external region of Env spikes. Nat.Chem.Biol., 16, 2020
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6W07
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![BU of 6w07 by Molmil](/molmil-images/mine/6w07) | Bruton's tyrosine kinase in complex with compound 1 | 分子名称: | DIMETHYL SULFOXIDE, Tyrosine-protein kinase BTK, ~{N}-[[2-methyl-4-[2-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]phenyl]methyl]-3-propan-2-yloxy-azetidine-1-carboxamide | 著者 | Metrick, C.M, Marcotte, D.J. | 登録日 | 2020-02-29 | 公開日 | 2020-12-16 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | 主引用文献 | Discovery of BIIB068: A Selective, Potent, Reversible Bruton's Tyrosine Kinase Inhibitor as an Orally Efficacious Agent for Autoimmune Diseases. J.Med.Chem., 63, 2020
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2NCT
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![BU of 2nct by Molmil](/molmil-images/mine/2nct) | NMR assignment and structure of a peptide derived from the membrane proximal external region of HIV-1 gp41 in the presence of hexafluoroisopropanol | 分子名称: | Envelope glycoprotein gp41 | 著者 | Jimenez, M, Nieva, J.L, Rujas, E, Partida-Hanon, A, Bruix, M. | 登録日 | 2016-04-14 | 公開日 | 2017-02-22 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural basis for broad neutralization of HIV-1 through the molecular recognition of 10E8 helical epitope at the membrane interface. Sci Rep, 6, 2016
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2NCS
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![BU of 2ncs by Molmil](/molmil-images/mine/2ncs) | NMR assignment and structure of a peptide derived from the membrane proximal external region of HIV-1 gp41 in the presence of dodecylphosphocholine micelles | 分子名称: | Envelope glycoprotein gp41 | 著者 | Jimenez, M, Nieva, J.L, Rujas, E, Partida-Hanon, A, Bruix, M. | 登録日 | 2016-04-14 | 公開日 | 2017-02-22 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural basis for broad neutralization of HIV-1 through the molecular recognition of 10E8 helical epitope at the membrane interface. Sci Rep, 6, 2016
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