6V4T
MPER-TMD of HIV-1 Env bound with the entry inhibitor S2C3
Summary for 6V4T
Entry DOI | 10.2210/pdb6v4t/pdb |
Related | 6E8W |
NMR Information | BMRB: 30503 |
Descriptor | Envelope glycoprotein gp160, 4,4'-(decane-1,10-diyl)bis(9-amino-2,3-dihydro-1H-cyclopenta[b]quinolin-4-ium) (2 entities in total) |
Functional Keywords | hiv-1 env, small-molecule, entry inhibitor, mper, viral protein |
Biological source | Human immunodeficiency virus 1 |
Total number of polymer chains | 3 |
Total formula weight | 20064.34 |
Authors | Xiao, T.,Frey, G.,Fu, Q.,Lavine, C.L.,Scott, D.A.,Seaman, M.S.,Chou, J.J.,Chen, B. (deposition date: 2019-11-30, release date: 2020-04-01, Last modification date: 2024-05-15) |
Primary citation | Xiao, T.,Frey, G.,Fu, Q.,Lavine, C.L.,Scott, D.A.,Seaman, M.S.,Chou, J.J.,Chen, B. HIV-1 fusion inhibitors targeting the membrane-proximal external region of Env spikes. Nat.Chem.Biol., 16:529-537, 2020 Cited by PubMed: 32152540DOI: 10.1038/s41589-020-0496-y PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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