7U8C

Crystal structure of Mesothelin C-terminal peptide-MORAb 15B6 FAB complex

This is a non-PDB format compatible entry.

Summary for 7U8C

• Entry DOI: 10.2210/pdb7u8c/pdb
• Descriptor: Mesothelin, cleaved form, MORab 15B6 Fab heavy chain, MORab 15B6 Fab light chain, ... (4 entities in total)
• Functional Keywords: mesothelin, immune system
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 3
• Total formula weight: 47526.91

Authors

Zhan, J.,Esser, L.,Xia, D. (deposition date: 2022-03-08, release date: 2022-06-08, Last modification date: 2023-10-18)

• Primary citation: Liu, X.,Onda, M.,Watson, N.,Hassan, R.,Ho, M.,Bera, T.K.,Wei, J.,Chakraborty, A.,Beers, R.,Zhou, Q.,Shajahan, A.,Azadi, P.,Zhan, J.,Xia, D.,Pastan, I.; Highly active CAR T cells that bind to a juxtamembrane region of mesothelin and are not blocked by shed mesothelin.; Proc.Natl.Acad.Sci.USA, 119:e2202439119-e2202439119, 2022; PubMed: 35512094; DOI: 10.1073/pnas.2202439119

Experimental method

X-RAY DIFFRACTION (1.74 Å)