PDB: 1544 件ウェブページステータス検索Chemie searchBIRD

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6JWI	Yeast Npl4 in complex with Lys48-linked diubiquitin 分子名称: BICINE, Nuclear protein localization protein 4, Ubiqutin, ... 著者 Sato, Y, Fukai, S. 登録日 2019-04-20 公開日 2019-12-25 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structural insights into ubiquitin recognition and Ufd1 interaction of Npl4. Nat Commun, 10, 2019
3L0W	Structure of split monoubiquitinated PCNA with ubiquitin in position two 分子名称: Monoubiquitinated Proliferating cell nuclear antigen, Proliferating cell nuclear antigen 著者 Freudenthal, B.D, Gakhar, L, Ramaswamy, S, Washington, M.T. 登録日 2009-12-10 公開日 2010-03-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure of monoubiquitinated PCNA and implications for translesion synthesis and DNA polymerase exchange. Nat.Struct.Mol.Biol., 17, 2010
6TXB	Crystal structure of Mindy1 mutant (P138A) in complex with Lys48 linked di-ubiquitin 分子名称: CHLORIDE ION, Polyubiquitin-C, SODIUM ION, ... 著者 Abdul Rehman, S.A, Kulathu, Y. 登録日 2020-01-14 公開日 2021-01-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.18 Å) 主引用文献 Mechanism of activation and regulation of deubiquitinase activity in MINDY1 and MINDY2. Mol.Cell, 81, 2021
6UKM	STING C-terminal Domain Complexed with Non-cyclic Dinucleotide Compound MSA-2 分子名称: 4-(5,6-dimethoxy-1-benzothiophen-2-yl)-4-oxobutanoic acid, fusion protein of Ubiquitin-like protein SMT3 and Stimulator of interferon protein c-terminal domain 著者 Lesburg, C.A. 登録日 2019-10-05 公開日 2020-08-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 An orally available non-nucleotide STING agonist with antitumor activity. Science, 369, 2020
5WQ4	Crystal structure of OPTN and linear diubiquitin complex 分子名称: Optineurin, ubiquitin 著者 Li, F, Pan, L. 登録日 2016-11-23 公開日 2017-12-06 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural insights into the ubiquitin recognition by OPTN (optineurin) and its regulation by TBK1-mediated phosphorylation. Autophagy, 14, 2018
3L10	Structure of split monoubiquitinated PCNA with ubiquitin in position one 分子名称: Monoubiquitinated Proliferating cell nuclear antigen, Proliferating cell nuclear antigen 著者 Freudenthal, B.D, Gakhar, L, Ramaswamy, S, Washington, M.T. 登録日 2009-12-10 公開日 2010-03-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure of monoubiquitinated PCNA and implications for translesion synthesis and DNA polymerase exchange. Nat.Struct.Mol.Biol., 17, 2010
6UKU	STING C-terminal Domain Complexed with Non-cyclic Dinucleotide Compound 3 分子名称: 4,4'-[propane-1,3-diylbis(6-methoxy-1-benzothiene-5,2-diyl)]bis(4-oxobutanoic acid), fusion protein of Ubiquitin-like protein SMT3 and Stimulator of interferon protein c-terminal domain 著者 Lesburg, C.A. 登録日 2019-10-06 公開日 2020-08-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 An orally available non-nucleotide STING agonist with antitumor activity. Science, 369, 2020
6UL0	STING C-terminal Domain Complexed with Non-cyclic Dinucleotide Compound 4 分子名称: 4-{5-[(1Z)-3-{[2-(3-carboxypropanoyl)-6-methoxy-1-benzothiophen-5-yl]oxy}prop-1-en-1-yl]-6-methoxy-1-benzothiophen-2-yl}-4-oxobutanoic acid, fusion protein of Ubiquitin-like protein SMT3 and Stimulator of interferon protein c-terminal domain 著者 Lesburg, C.A. 登録日 2019-10-06 公開日 2020-08-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 An orally available non-nucleotide STING agonist with antitumor activity. Science, 369, 2020
3LDZ	Crystal structure of human STAM1 VHS domain in complex with ubiquitin 分子名称: Signal transducing adapter molecule 1, Ubiquitin 著者 Ren, X, Hurley, J.H. 登録日 2010-01-13 公開日 2010-03-02 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 VHS domains of ESCRT-0 cooperate in high-avidity binding to polyubiquitinated cargo. Embo J., 29, 2010
6UKV	STING C-terminal Domain Complexed with Non-cyclic Dinucleotide Compound 9 分子名称: 4-[6-(3-{[2-(3-carboxypropanoyl)-6-methoxy-1-benzothiophen-5-yl]oxy}propoxy)-5-methoxy-1-benzothiophen-2-yl]-4-oxobutanoic acid, fusion protein of Ubiquitin-like protein SMT3 and Stimulator of interferon protein c-terminal domain 著者 Lesburg, C.A. 登録日 2019-10-06 公開日 2020-08-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 An orally available non-nucleotide STING agonist with antitumor activity. Science, 369, 2020
5XBO	Lanthanoid tagging via an unnatural amino acid for protein structure characterization 分子名称: Polyubiquitin-B, TERBIUM(III) ION, UV excision repair protein RAD23 homolog A 著者 Jiang, W, Gu, X, Dong, X, Tang, C. 登録日 2017-03-21 公開日 2017-05-31 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Lanthanoid tagging via an unnatural amino acid for protein structure characterization J. Biomol. NMR, 67, 2017
6UYJ	hRpn13:hRpn2:K48-diubiquitin 分子名称: 26S proteasome non-ATPase regulatory subunit 1, Proteasomal ubiquitin receptor ADRM1, Ubiquitin 著者 Lu, X, Walters, K.J. 登録日 2019-11-13 公開日 2020-03-11 最終更新日 2020-05-20 実験手法 SOLUTION NMR 主引用文献 An Extended Conformation for K48 Ubiquitin Chains Revealed by the hRpn2:Rpn13:K48-Diubiquitin Structure. Structure, 28, 2020
5XU8	Crystal structure of human USP2 in complex with ubiquitin and 6-thioguanine 分子名称: 2-amino-1,9-dihydro-6H-purine-6-thione, CHLORIDE ION, SODIUM ION, ... 著者 Chou, C.Y, Chuang, S.J. 登録日 2017-06-22 公開日 2018-02-28 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 6-Thioguanine is a noncompetitive and slow binding inhibitor of human deubiquitinating protease USP2 Sci Rep, 8, 2018
6VAF	Structure of mono-ubiquitinated FANCD2 bound to non-ubiquitinated FANCI and to DNA 分子名称: DNA (29-MER), Fanconi anemia group D2 protein, Fanconi anemia, ... 著者 Pavletich, N.P. 登録日 2019-12-17 公開日 2020-03-18 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 DNA clamp function of the monoubiquitinated Fanconi anaemia ID complex. Nature, 580, 2020
5XVE	Crystal structure of human USP2 C276S mutant in complex with ubiquitin 分子名称: Ubiquitin carboxyl-terminal hydrolase 2, Ubiquitin-40S ribosomal protein S27a, ZINC ION 著者 Chou, C.Y, Tang, H.C. 登録日 2017-06-27 公開日 2018-02-28 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.24 Å) 主引用文献 6-Thioguanine is a noncompetitive and slow binding inhibitor of human deubiquitinating protease USP2 Sci Rep, 8, 2018
6UPU	Crystal structure of the Orientia tsutsugamushi OtDUB in complex with three molecules of ubiquitin 分子名称: ULP_PROTEASE domain-containing protein, Ubiquitin 著者 Lim, C.S, Ronau, J.A, Xiong, Y. 登録日 2019-10-18 公開日 2020-04-01 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 A deubiquitylase with an unusually high-affinity ubiquitin-binding domain from the scrub typhus pathogen Orientia tsutsugamushi. Nat Commun, 11, 2020
6UYI	hRpn13:hRpn2:K48-diubiquitin 分子名称: 26S proteasome non-ATPase regulatory subunit 1, Proteasomal ubiquitin receptor ADRM1, Ubiquitin 著者 Lu, X, Walters, K.J. 登録日 2019-11-13 公開日 2020-03-11 最終更新日 2022-03-16 実験手法 SOLUTION NMR 主引用文献 An Extended Conformation for K48 Ubiquitin Chains Revealed by the hRpn2:Rpn13:K48-Diubiquitin Structure. Structure, 28, 2020
6VAE	Mono-ubiquitinated Fanconi Anemia ID complex bound to ICL DNA 分子名称: DNA (29-MER), Fanconi anemia group D2 protein, Fanconi anemia, ... 著者 Pavletich, N.P. 登録日 2019-12-17 公開日 2020-03-18 最終更新日 2020-04-22 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 DNA clamp function of the monoubiquitinated Fanconi anaemia ID complex. Nature, 580, 2020
3M63	Crystal structure of Ufd2 in complex with the ubiquitin-like (UBL) domain of Dsk2 分子名称: PENTAETHYLENE GLYCOL, POTASSIUM ION, Ubiquitin conjugation factor E4, ... 著者 Haenzelmann, P, Schindelin, H. 登録日 2010-03-15 公開日 2010-04-28 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The yeast E4 ubiquitin ligase Ufd2 interacts with the ubiquitin-like domains of Rad23 and Dsk2 via a novel and distinct ubiquitin-like binding domain. J.Biol.Chem., 285, 2010
5YT6	Crystal structure of TAX1BP1 UBZ2 in complex with mono-ubiquitin 分子名称: 1,2-ETHANEDIOL, GLYCEROL, SULFATE ION, ... 著者 Pan, L, Hu, S. 登録日 2017-11-17 公開日 2018-07-11 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.501 Å) 主引用文献 Mechanistic Insights into Recognitions of Ubiquitin and Myosin VI by Autophagy Receptor TAX1BP1. J. Mol. Biol., 430, 2018
5YDR	Structure of DNMT1 RFTS domain in complex with ubiquitin 分子名称: DNA (cytosine-5)-methyltransferase 1, PHOSPHATE ION, Polyubiquitin-B, ... 著者 Qian, C. 登録日 2017-09-14 公開日 2018-02-21 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.003 Å) 主引用文献 Structural and mechanistic insights into UHRF1-mediated DNMT1 activation in the maintenance DNA methylation. Nucleic Acids Res., 46, 2018
6UKX	STING C-terminal Domain Complexed with Non-cyclic Dinucleotide Compound 11 分子名称: 4,4'-{propane-1,3-diylbis[oxy(5-methoxy-1-benzothiene-6,2-diyl)]}bis(4-oxobutanoic acid), fusion protein of Ubiquitin-like protein SMT3 and Stimulator of interferon protein c-terminal domain 著者 Lesburg, C.A. 登録日 2019-10-06 公開日 2020-08-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 An orally available non-nucleotide STING agonist with antitumor activity. Science, 369, 2020
6UKZ	STING C-terminal Domain Complexed with Non-cyclic Dinucleotide Compound 6 分子名称: 4-[5-(2-{[2-(3-carboxypropanoyl)-4-fluoro-6-methoxy-1-benzothiophen-5-yl]oxy}ethoxy)-6-methoxy-1-benzothiophen-2-yl]-4-oxobutanoic acid, fusion protein of Ubiquitin-like protein SMT3 and Stimulator of interferon protein c-terminal domain 著者 Lesburg, C.A. 登録日 2019-10-06 公開日 2020-08-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 An orally available non-nucleotide STING agonist with antitumor activity. Science, 369, 2020
5YIK	Structure of a Legionella effector with its substrate 分子名称: SdeA, ubiquitin 著者 Feng, Y, Dong, Y, Liu, Z. 登録日 2017-10-05 公開日 2018-05-30 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.102 Å) 主引用文献 Structural basis of ubiquitin modification by the Legionella effector SdeA. Nature, 557, 2018
3MHS	Structure of the SAGA Ubp8/Sgf11/Sus1/Sgf73 DUB module bound to ubiquitin aldehyde 分子名称: 1,2-ETHANEDIOL, GLYCEROL, Protein SUS1, ... 著者 Samara, N.L, Datta, A.B, Berndsen, C.E, Zhang, X, Yao, T, Cohen, R.E, Wolberger, C. 登録日 2010-04-08 公開日 2010-04-21 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Structural insights into the assembly and function of the SAGA deubiquitinating module. Science, 328, 2010

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