PDB: 13422 件ウェブページステータス検索Chemie searchBIRD

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3O7L	Crystal Structure of phospholamban (1-19):PKA C-subunit:AMP-PNP:Mg2+ complex 分子名称: Cardiac phospholamban, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... 著者 Cheng, C.Y, Taylor, S.S. 登録日 2010-07-30 公開日 2010-10-06 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Dynamics connect substrate recognition to catalysis in protein kinase A. Nat.Chem.Biol., 6, 2010
2QEQ	Crystal structure of kunjin virus ns3 helicase 分子名称: Flavivirin protease NS3 catalytic subunit 著者 Milani, M, Mastrangelo, E, Bolognesi, M. 登録日 2007-06-26 公開日 2007-08-14 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Crystal structure and activity of Kunjin virus NS3 helicase; protease and helicase domain assembly in the full length NS3 protein J.Mol.Biol., 372, 2007
3GLI	Crystal Structure of the E. coli clamp loader bound to Primer-Template DNA and Psi Peptide 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA (5'-D(*CP*TP*GP*GP*CP*CP*TP*AP*TP*A)-3'), ... 著者 Simonetta, K.R, Cantor, A.J, Kuriyan, J. 登録日 2009-03-12 公開日 2009-05-26 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 The mechanism of ATP-dependent primer-template recognition by a clamp loader complex. Cell(Cambridge,Mass.), 137, 2009
3GLH	Crystal Structure of the E. coli clamp loader bound to Psi Peptide 分子名称: DNA polymerase III subunit delta, DNA polymerase III subunit delta', DNA polymerase III subunit tau 著者 Kazmirski, S.L, Simonetta, K.R, Kuriyan, J. 登録日 2009-03-12 公開日 2009-05-26 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.891 Å) 主引用文献 The mechanism of ATP-dependent primer-template recognition by a clamp loader complex. Cell(Cambridge,Mass.), 137, 2009
6OEV	Structure of human Patched1 in complex with native Sonic Hedgehog 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Protein patched homolog 1, ... 著者 Qi, X, Li, X. 登録日 2019-03-27 公開日 2019-04-17 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structures of human Patched and its complex with native palmitoylated sonic hedgehog. Nature, 560, 2018
3L9Q	Crystal structure of human polymerase alpha-primase p58 iron-sulfur cluster domain 分子名称: DNA primase large subunit, IRON/SULFUR CLUSTER, SULFATE ION 著者 Vaithiyalingam, S, Eichman, B.F, Chazin, W.J. 登録日 2010-01-05 公開日 2010-07-14 最終更新日 2011-11-16 実験手法 X-RAY DIFFRACTION (1.698 Å) 主引用文献 Insights into eukaryotic DNA priming from the structure and functional interactions of the 4Fe-4S cluster domain of human DNA primase. Proc.Natl.Acad.Sci.USA, 107, 2010
6OEU	Structure of human Patched1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Protein patched homolog 1 著者 Qi, X, Li, X, Wang, J. 登録日 2019-03-27 公開日 2019-04-10 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structures of human Patched and its complex with native palmitoylated sonic hedgehog. Nature, 560, 2018
5BQD	Crystal Structure of TBX5 (1-239) Dimer 分子名称: MAGNESIUM ION, T-box transcription factor TBX5 著者 Pradhan, L, Gopal, S, Patel, A, Kasahara, H, Nam, H.J. 登録日 2015-05-28 公開日 2016-03-16 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.583 Å) 主引用文献 Intermolecular Interactions of Cardiac Transcription Factors NKX2.5 and TBX5. Biochemistry, 55, 2016
2C6A	Solution structure of the C4 zinc-finger domain of HDM2 分子名称: UBIQUITIN-PROTEIN LIGASE E3 MDM2, ZINC ION 著者 Yu, G.W, Allen, M.D, Andreeva, A, Fersht, A.R, Bycroft, M. 登録日 2005-11-08 公開日 2006-01-04 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution Structure of the C4 Zinc Finger Domain of Hdm2. Protein Sci., 15, 2006
1JVP	Crystal structure of human CDK2 (unphosphorylated) in complex with PKF049-365 分子名称: 3-pyridin-4-yl-2,4-dihydroindeno[1,2-c]pyrazole, Cell division protein kinase 2 著者 Rondeau, J.M. 登録日 2001-08-31 公開日 2001-12-21 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Structure-based design and protein X-ray analysis of a protein kinase inhibitor. Bioorg.Med.Chem.Lett., 12, 2002
7QJ9	Structure of recombinant human gamma-Tubulin Ring Complex 10-spoked assembly intermediate (spokes 3-12, homogeneous dataset) 分子名称: Gamma-tubulin complex component 2, Gamma-tubulin complex component 3, Gamma-tubulin complex component 4, ... 著者 Zupa, E, Pfeffer, S. 登録日 2021-12-16 公開日 2022-01-26 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (8.1 Å) 主引用文献 Modular assembly of the principal microtubule nucleator gamma-TuRC. Nat Commun, 13, 2022
7QJ6	Structure of recombinant human gamma-Tubulin Ring Complex 10-spoked assembly intermediate (spokes 3-12, substoichiometric spokes 13-14) 分子名称: Gamma-tubulin complex component 2, Gamma-tubulin complex component 3, Gamma-tubulin complex component 4, ... 著者 Zupa, E, Pfeffer, S. 登録日 2021-12-16 公開日 2022-01-26 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (7.8 Å) 主引用文献 Modular assembly of the principal microtubule nucleator gamma-TuRC. Nat Commun, 13, 2022
1FTA	FRUCTOSE-1,6-BISPHOSPHATASE(D-FRUCTOSE-1,6-BISPHOSPHATE, 1-PHOSPHOHYDROLASE) (E.C.3.1.3.11) COMPLEXED WITH THE ALLOSTERIC INHIBITOR AMP 分子名称: ADENOSINE MONOPHOSPHATE, FRUCTOSE-1,6-BISPHOSPHATASE 著者 Zhang, Y, Liang, J.-Y, Huang, S, Lipscomb, W.N. 登録日 1993-09-27 公開日 1995-11-14 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The allosteric site of human liver fructose-1,6-bisphosphatase. Analysis of six AMP site mutants based on the crystal structure. J.Biol.Chem., 269, 1994
8G0Z	Mutant bacteriophage T4 gp41 helicase hexamer bound with single strand DNA and ATPgammaS in the stalled primosome 分子名称: DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DnaB-like replicative helicase, MAGNESIUM ION, ... 著者 Feng, X, Li, H. 登録日 2023-02-01 公開日 2023-06-14 最終更新日 2023-08-23 実験手法 ELECTRON MICROSCOPY (3.61 Å) 主引用文献 Structural basis of the T4 bacteriophage primosome assembly and primer synthesis. Nat Commun, 14, 2023
2MXD	Solution structure of VPg of porcine sapovirus 分子名称: Viral protein genome-linked 著者 Kim, J, Hwang, H, Min, H, Yun, H, Cho, K, Pelton, J.G, Wemmer, D.E, Lee, C. 登録日 2014-12-24 公開日 2015-04-15 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution structure of the porcine sapovirus VPg core reveals a stable three-helical bundle with a conserved surface patch. Biochem.Biophys.Res.Commun., 459, 2015
5J9S	ENL YEATS in complex with histone H3 acetylation at K27 分子名称: H3K27ac peptide from Histone H3.1, Protein ENL, SULFATE ION 著者 Li, Y, Li, H. 登録日 2016-04-11 公開日 2017-03-08 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.702 Å) 主引用文献 ENL links histone acetylation to oncogenic gene expression in acute myeloid leukaemia Nature, 543, 2017
2C6B	Solution structure of the C4 zinc-finger domain of HDM2 分子名称: UBIQUITIN-PROTEIN LIGASE E3 MDM2, ZINC ION 著者 Yu, G.W, Allen, M.D, Andreeva, A, Fersht, A.R, Bycroft, M. 登録日 2005-11-08 公開日 2006-01-04 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution Structure of the C4 Zinc Finger Domain of Hdm2. Protein Sci., 15, 2006
2P5G	Crystal structure of RB69 gp43 in complex with DNA with dAMP opposite an abasic site analog in a 21mer template 分子名称: DNA polymerase, Primer DNA, Template DNA 著者 Zahn, K.E, Belrhali, H, Wallace, S.S, Doublie, S. 登録日 2007-03-15 公開日 2007-10-23 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Caught bending the a-rule: crystal structures of translesion DNA synthesis with a non-natural nucleotide. Biochemistry, 46, 2007
2OZM	Crystal structure of RB69 gp43 in complex with DNA with 5-NITP opposite an abasic site analog 分子名称: 1-{2-DEOXY-5-O-[(R)-HYDROXY{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}PHOSPHORYL]-BETA-D-ERYTHRO-PENTOFURANOSYL}-5-NITRO -1H-INDOLE, DNA polymerase, MAGNESIUM ION, ... 著者 Zahn, K.E, Belrhali, H, Wallace, S.S, Doublie, S. 登録日 2007-02-26 公開日 2007-10-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.86 Å) 主引用文献 Caught Bending the A-Rule: crystal structures of translesion DNA synthesis with a non-natural nucleotide Biochemistry, 46, 2007
5CYI	CDK2/Cyclin A covalent complex with 6-(cyclohexylmethoxy)-N-(4-(vinylsulfonyl)phenyl)-9H-purin-2-amine (NU6300) 分子名称: 6-(cyclohexylmethoxy)-N-[4-(ethylsulfonyl)phenyl]-9H-purin-2-amine, Cyclin-A2, Cyclin-dependent kinase 2 著者 Anscombe, E, Meschini, E, Vidal, R.M, Martin, M.P, Staunton, D, Geitmann, M, Danielson, U.H, Stanley, W.A, Wang, L.Z, Reuillon, T, Golding, B.T, Cano, C, Newell, D.R, Noble, M.E.M, Wedge, S.R, Endicott, J.A, Griffin, R.J. 登録日 2015-07-30 公開日 2015-09-16 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Identification and Characterization of an Irreversible Inhibitor of CDK2. Chem.Biol., 22, 2015
2OZS	Crystal structure of RB69 gp43 in complex with DNA with dATP opposite dTMP 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA polymerase, MAGNESIUM ION, ... 著者 Zahn, K.E, Belrhali, H, Wallace, S.S, Doublie, S. 登録日 2007-02-27 公開日 2007-10-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Caught bending the a-rule: crystal structures of translesion DNA synthesis with a non-natural nucleotide. Biochemistry, 46, 2007
3N8B	Crystal Structure of Borrelia burgdorferi Pur-alpha 分子名称: 1,2-ETHANEDIOL, MAGNESIUM ION, Uncharacterized protein 著者 Graebsch, A, Roche, S, Kostrewa, D, Niessing, D. 登録日 2010-05-28 公開日 2010-10-06 最終更新日 2018-02-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Of bits and bugs--on the use of bioinformatics and a bacterial crystal structure to solve a eukaryotic repeat-protein structure. Plos One, 5, 2010
5BJS	Apo ctPRC2 in an autoinhibited state 分子名称: Histone-lysine N-methyltransferase EZH2, Polycomb protein SUZ12, Polycomb Protein EED, ... 著者 Bratkowski, M.A, Liu, X. 登録日 2016-10-22 公開日 2017-06-14 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.189 Å) 主引用文献 Polycomb repressive complex 2 in an autoinhibited state. J. Biol. Chem., 292, 2017
2OYQ	Crystal structure of RB69 gp43 in complex with DNA with 5-NIMP opposite an abasic site analog 分子名称: 1-{2-DEOXY-5-O-[(R)-HYDROXY{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}PHOSPHORYL]-BETA-D-ERYTHRO-PENTOFURANOSYL}-5-NITRO -1H-INDOLE, DNA polymerase, MAGNESIUM ION, ... 著者 Zahn, K.E, Belrhali, H, Wallace, S.S, Doublie, S. 登録日 2007-02-22 公開日 2007-10-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.86 Å) 主引用文献 Caught bending the a-rule: crystal structures of translesion DNA synthesis with a non-natural nucleotide. Biochemistry, 46, 2007
4GV7	Human ARTD1 (PARP1) - Catalytic domain in complex with inhibitor ME0328 分子名称: 2-methylquinazolin-4(3H)-one, Poly [ADP-ribose] polymerase 1 著者 Karlberg, T, Thorsell, A.G, Lindgren, A.E.G, Ekblad, T, Spjut, S, Andersson, C.D, Weigelt, J, Linusson, A, Elofsson, M, Schuler, H. 登録日 2012-08-30 公開日 2013-06-19 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.89 Å) 主引用文献 PARP Inhibitor with Selectivity Toward ADP-Ribosyltransferase ARTD3/PARP3 Acs Chem.Biol., 8, 2013

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