PDB: 9760 件ウェブページステータス検索Chemie searchBIRD

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4ZI7	CRYSTAL STRUCTURE OF TUBULIN-STATHMIN-TTL-HTI286 COMPLEX 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GLYCEROL, ... 著者 Wang, Y, Zhang, R. 登録日 2015-04-27 公開日 2016-07-27 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 Structural Insights into the Pharmacophore of Vinca Domain Inhibitors of Microtubules Mol.Pharmacol., 89, 2016
5BMV	CRYSTAL STRUCTURE OF TUBULIN-STATHMIN-TTL-Vinblastine COMPLEX 分子名称: (2ALPHA,2'BETA,3BETA,4ALPHA,5BETA)-VINCALEUKOBLASTINE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... 著者 Wang, Y, Chen, Q, Zhang, R. 登録日 2015-05-23 公開日 2016-07-13 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural Insights into the Pharmacophore of Vinca Domain Inhibitors of Microtubules. Mol.Pharmacol., 89, 2016
3OAZ	A non-self sugar mimic of the HIV glycan shield shows enhanced antigenicity 分子名称: CHLORIDE ION, Fab 2G12, heavy chain, ... 著者 Doores, K.J, Fulton, Z, Hong, V, Patel, M.K, Scanlan, C.N, Wormald, M.R, Finn, M.G, Burton, D.R, Wilson, I.A, Davis, B.G. 登録日 2010-08-06 公開日 2011-01-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity. Proc.Natl.Acad.Sci.USA, 107, 2010
3OAY	A non-self sugar mimic of the HIV glycan shield shows enhanced antigenicity 分子名称: Fab 2G12, heavy chain, light chain, ... 著者 Doores, K.J, Fulton, Z, Hong, V, Patel, M.K, Scanlan, C.N, Wormald, M.R, Finn, M.G, Burton, D.R, Wilson, I.A, Davis, B.G. 登録日 2010-08-05 公開日 2011-01-12 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity. Proc.Natl.Acad.Sci.USA, 107, 2010
3OB0	A non-self sugar mimic of the HIV glycan shield shows enhanced antigenicity 分子名称: 7-deoxy-L-glycero-alpha-D-manno-heptopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose, Fab 2G12, heavy chain, ... 著者 Doores, K.J, Fulton, Z, Hong, V, Patel, M.K, Scanlan, C.N, Wormald, M.R, Finn, M.G, Burton, D.R, Wilson, I.A, Davis, B.G. 登録日 2010-08-06 公開日 2011-01-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity. Proc.Natl.Acad.Sci.USA, 107, 2010
5SWK	Crystal structure of p53 epitope-scaffold based on a inhibitor of cysteine proteases in complex with human MDM2 分子名称: CHLORIDE ION, De novo protein based on the inhibitor Amoebiasin-1, E3 ubiquitin-protein ligase Mdm2, ... 著者 Jimenez-Sandoval, P, Brieba, L.G. 登録日 2016-08-08 公開日 2017-10-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.923 Å) 主引用文献 Mimicking a p53-MDM2 interaction based on a stable immunoglobulin-like domain scaffold. Proteins, 86, 2018
8BL3	De novo single-chain immunoglobulin dimer scIg12 分子名称: GLYCEROL, scIg12 著者 Nadal, M, Roel-Touris, J, Marcos, E. 登録日 2022-11-09 公開日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Single-chain dimers from de novo immunoglobulins as robust scaffolds for multiple binding loops. Nat Commun, 14, 2023
8BL6	De novo single-chain immunoglobulin dimer scIg12+EF3a 分子名称: GLYCEROL, TERBIUM(III) ION, dIG14-scdim-EF62 著者 Nadal, M, Roel-Touris, J, Marcos, E. 登録日 2022-11-09 公開日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Single-chain dimers from de novo immunoglobulins as robust scaffolds for multiple binding loops. Nat Commun, 14, 2023
6CJC	CRYSTAL STRUCTURE OF A FC FRAGMENT LALA MUTANT (L234A, L235A) OF HUMAN IGG1 (CRYSTAL FORM 3) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Uncharacterized protein DKFZp686C11235 著者 Tolbert, W.D, Van, V, Pazgier, M. 登録日 2018-02-26 公開日 2019-03-06 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.575 Å) 主引用文献 Antigen-Induced Allosteric Changes in a Human IgG1 Fc Increase Low-Affinity Fc gamma Receptor Binding. Structure, 28, 2020
6CHF	Crystal structure of a Fc fragment LALA mutant (L234A, L235A) of human IgG1 (crystal form 1) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Uncharacterized protein DKFZp686C11235 著者 Gohain, N, Tolbert, W.D, Pazgier, M. 登録日 2018-02-22 公開日 2019-02-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Antigen-Induced Allosteric Changes in a Human IgG1 Fc Increase Low-Affinity Fc gamma Receptor Binding. Structure, 2020
5LAX	Crystal structure of HLA_DRB1*04:01 in complex with alpha-enolase peptide 26-40 分子名称: HLA class II histocompatibility antigen, DR alpha chain, DRB1-4 beta chain, ... 著者 Dubnovitsky, A, Kozhukh, G, Sandalova, T, Achour, A. 登録日 2016-06-15 公開日 2016-12-07 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Functional and Structural Characterization of a Novel HLA-DRB1*04:01-Restricted alpha-Enolase T Cell Epitope in Rheumatoid Arthritis. Front Immunol, 7, 2016
5JLZ	Crystal structure of HLA-DRB1*04:01 in complex with modified alpha-enolase peptide 26-40 with citrulline at the position 32 分子名称: Alpha-enolase, HLA class II histocompatibility antigen, DR alpha chain, ... 著者 Dubnovitsky, A, Kozhukh, G, Sandalova, T, Achour, A. 登録日 2016-04-28 公開日 2016-12-07 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Functional and Structural Characterization of a Novel HLA-DRB1*04:01-Restricted alpha-Enolase T Cell Epitope in Rheumatoid Arthritis. Front Immunol, 7, 2016
4K5C	From DARPins to LoopDARPins: Novel LoopDARPin Design Allows the Selection of Low Picomolar Binders in a Single Round of Ribosome Display 分子名称: Loop Designed Ankyrin Repeat Protein Nran1_G06_C 著者 Schilling, J, Schoeppe, J, Plueckthun, A. 登録日 2013-04-14 公開日 2013-11-13 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 From DARPins to LoopDARPins: novel LoopDARPin design allows the selection of low picomolar binders in a single round of ribosome display J.Mol.Biol., 426, 2014
7NS6	SARS-CoV-2 Spike (dimers) in complex with six Fu2 nanobodies 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fu2 nanobody, Spike glycoprotein,Fibritin, ... 著者 Das, H, Hallberg, B.M. 登録日 2021-03-05 公開日 2022-02-02 実験手法 ELECTRON MICROSCOPY (3.18 Å) 主引用文献 A bispecific monomeric nanobody induces spike trimer dimers and neutralizes SARS-CoV-2 in vivo. Nat Commun, 13, 2022
5NIU	Structure of human Programmed cell death 1 ligand 1 (PD-L1) with low molecular mass inhibitor 分子名称: (2~{R})-2-[[2-[(3-cyanophenyl)methoxy]-4-[[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methyl-phenyl]methoxy]-5-methyl-phenyl]methylamino]-3-oxidanyl-propanoic acid, 1,2-ETHANEDIOL, Programmed cell death 1 ligand 1 著者 Zak, K.M, Grudnik, P, Skalniak, L, Dubin, G, Holak, T.A. 登録日 2017-03-27 公開日 2017-12-06 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Small-molecule inhibitors of PD-1/PD-L1 immune checkpoint alleviate the PD-L1-induced exhaustion of T-cells. Oncotarget, 8, 2017
3VCM	Crystal structure of human prorenin 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, prorenin 著者 Morales, R, Watier, Y, Bocskei, Z. 登録日 2012-01-04 公開日 2012-05-23 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.93 Å) 主引用文献 Human Prorenin Structure Sheds Light on a Novel Mechanism of Its Autoinhibition and on Its Non-Proteolytic Activation by the (Pro)renin Receptor. J.Mol.Biol., 421, 2012
7NLL	SARS-CoV-2 Spike RBD (dimer) in complex with two Fu2 nanobodies 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody Fu2, Spike protein S1 著者 Das, H, Hallberg, B.M. 登録日 2021-02-22 公開日 2022-02-02 最終更新日 2023-09-27 実験手法 ELECTRON MICROSCOPY (2.89 Å) 主引用文献 A bispecific monomeric nanobody induces spike trimer dimers and neutralizes SARS-CoV-2 in vivo. Nat Commun, 13, 2022
2W1M	THE INTERDEPENDENCE OF WAVELENGTH, REDUNDANCY AND DOSE IN SULFUR SAD EXPERIMENTS: 2.070 A WAVELENGTH with 2theta 30 degrees data 分子名称: CHLORIDE ION, LYSOZYME C, SODIUM ION 著者 Cianci, M, Helliwell, J.R, Suzuki, A. 登録日 2008-10-17 公開日 2008-11-04 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 The Interdependence of Wavelength, Redundancy and Dose in Sulfur Sad Experiments. Acta Crystallogr.,Sect.D, 64, 2008
2W1Y	THE INTERDEPENDENCE OF WAVELENGTH, REDUNDANCY AND DOSE IN SULFUR SAD EXPERIMENTS: 1.540 A wavelength 180 images data 分子名称: CHLORIDE ION, LYSOZYME C, SODIUM ION 著者 Cianci, M, Helliwell, J.R, Suzuki, A. 登録日 2008-10-21 公開日 2008-11-25 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 The Interdependence of Wavelength, Redundancy and Dose in Sulfur Sad Experiments. Acta Crystallogr.,Sect.D, 64, 2008
2W1L	THE INTERDEPENDENCE OF WAVELENGTH, REDUNDANCY AND DOSE IN SULFUR SAD EXPERIMENTS: 0.979 a wavelength 991 images data 分子名称: CHLORIDE ION, LYSOZYME C, SODIUM ION 著者 Cianci, M, Helliwell, J.R, Suzuki, A. 登録日 2008-10-17 公開日 2008-10-28 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.51 Å) 主引用文献 The Interdependence of Wavelength, Redundancy and Dose in Sulfur Sad Experiments. Acta Crystallogr.,Sect.D, 64, 2008
2W1X	The interdependence of wavelength, redundancy and dose in sulfur SAD experiments: 1.284 A wavelength 360 images data 分子名称: CHLORIDE ION, LYSOZYME C, SODIUM ION 著者 Cianci, M, Helliwell, J.R, Suzuki, A. 登録日 2008-10-21 公開日 2008-11-04 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The Interdependence of Wavelength, Redundancy and Dose in Sulfur Sad Experiments. Acta Crystallogr.,Sect.D, 64, 2008
3ZVQ	Crystal Structure of proteolyzed lysozyme 分子名称: LYSOZYME C 著者 Kishan, K.V, Sharma, A. 登録日 2011-07-26 公開日 2011-10-19 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Salt-assisted religation of proteolyzed Glutathione-S-transferase follows Hofmeister series. Protein Pept.Lett., 17, 2010
6ICF	The NZ-1 Fab complexed with the PDZ tandem fragment of A. aeolicus S2P homolog with the PA12 tag inserted between the residues 263 and 266 分子名称: Heavy chain of antigen binding fragment, Fab of NZ-1, Light chain of antigen binding fragment, ... 著者 Tamura, R, Oi, R, Kaneko, M.K, Kato, Y, Nogi, T. 登録日 2018-09-05 公開日 2019-02-13 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (4 Å) 主引用文献 Application of the NZ-1 Fab as a crystallization chaperone for PA tag-inserted target proteins. Protein Sci., 28, 2019
6ICC	The NZ-1 Fab complexed with the PDZ tandem fragment of A. aeolicus S2P homolog with the PA12 tag inserted between the residues 181 and 186 分子名称: Heavy chain of antigen binding fragment, Fab of NZ-1, Light chain of antigen binding fragment, ... 著者 Tamura, R, Oi, R, Kaneko, M.K, Kato, Y, Nogi, T. 登録日 2018-09-05 公開日 2019-02-13 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Application of the NZ-1 Fab as a crystallization chaperone for PA tag-inserted target proteins. Protein Sci., 28, 2019
4AGA	Hofmeister effects of ionic liquids in protein crystallization: direct and water-mediated interactions 分子名称: ACETATE ION, CHLORIDE ION, CHOLINE ION, ... 著者 Mukhopadhyay, A, Carvalho, A.L, Romao, M.J. 登録日 2012-01-25 公開日 2012-07-18 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Hofmeister Effects of Ionic Liquids in Protein Crystallization: Direct and Water-Mediated Interactions Cryst.Eng.Comm., 14, 2012

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