PDB: 13252 件ウェブページステータス検索Chemie searchBIRD

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8CHW	Crystal structure of human PURA (fragment Pro216-Lys280, PUR repeat III) 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Transcriptional activator protein Pur-alpha 著者 Janowski, R, Niessing, D. 登録日 2023-02-08 公開日 2024-02-21 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 PURA syndrome-causing mutations impair PUR-domain integrity and affect P-body association. Elife, 13, 2024
8CHT	Crystal structure of human PURA (fragment Glu57-Glu212, PUR repeat I and II) 分子名称: 1,2-ETHANEDIOL, ACETATE ION, Transcriptional activator protein Pur-alpha 著者 Janowski, R, Niessing, D. 登録日 2023-02-08 公開日 2024-02-21 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 PURA syndrome-causing mutations impair PUR-domain integrity and affect P-body association. Elife, 13, 2024
8CHV	Crystal structure of human PURA (fragment Glu57-Glu212, PUR repeat I and II) R140P mutant 分子名称: Transcriptional activator protein Pur-alpha 著者 Janowski, R, Niessing, D. 登録日 2023-02-08 公開日 2024-02-21 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 PURA syndrome-causing mutations impair PUR-domain integrity and affect P-body association. Elife, 13, 2024
4O22	Binary complex of metal-free PKAc with SP20. 分子名称: Phosphorylated peptide pSP20., cAMP-dependent protein kinase catalytic subunit alpha. 著者 Das, A, Kovalevsky, A.Y, Gerlits, O, Langan, P, Heller, W.T, Keshwani, M, Taylor, S.S. 登録日 2013-12-16 公開日 2014-05-28 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Metal-Free cAMP-Dependent Protein Kinase Can Catalyze Phosphoryl Transfer. Biochemistry, 53, 2014
8CHU	Crystal structure of human PURA repeat I-II K97E mutant 分子名称: 1,2-ETHANEDIOL, MAGNESIUM ION, Transcriptional activator protein Pur-alpha 著者 Janowski, R, Niessing, D. 登録日 2023-02-08 公開日 2024-02-21 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 PURA syndrome-causing mutations impair PUR-domain integrity and affect P-body association. Elife, 13, 2024
4O21	Product complex of metal-free PKAc, ATP-gamma-S and SP20. 分子名称: ADENOSINE-5'-DIPHOSPHATE, Thio-phosphorylated peptide pSP20, cAMP-dependent protein kinase catalytic subunit alpha 著者 Das, A, Kovalevsky, A.Y, Gerlits, O, Langan, P, Heller, W.T, Keshwani, M, Taylor, S. 登録日 2013-12-16 公開日 2014-05-28 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Metal-Free cAMP-Dependent Protein Kinase Can Catalyze Phosphoryl Transfer. Biochemistry, 53, 2014
3QEX	RB69 DNA Polymerase (L561A/S565G/Y567A) Ternary Complex with dGTP Opposite dT 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ... 著者 Xia, S, Konigsberg, W.H, Wang, J. 登録日 2011-01-20 公開日 2012-01-25 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Hydrogen-Bonding Capability of Difluorotoluene Nucleoside in Replication Complexes To be Published
2A4O	Dual modes of modification of Hepatitis A virus 3C protease by a serine derived beta-lactone: selective crytstallization and high resolution structure of the His102 adduct 分子名称: ACETYL GROUP, N-[(BENZYLOXY)CARBONYL]-L-ALANINE, PHENYLALANINE AMIDE, ... 著者 Yin, J, Bergmann, E.M, Cherney, M.M, Lall, M.S, Jain, R.P, Vederas, J.C, James, M.N.G. 登録日 2005-06-29 公開日 2005-12-27 最終更新日 2021-11-10 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Dual Modes of Modification of Hepatitis A Virus 3C Protease by a Serine-derived beta-Lactone: Selective Crystallization and Formation of a Functional Catalytic Triad in the Active Site J.MOL.BIOL., 354, 2005
1KXC	SINDBIS VIRUS CAPSID (N190K MUTANT), TETRAGONAL CRYSTAL FORM 分子名称: SINDBIS VIRUS CAPSID PROTEIN 著者 Choi, H.-K, Rossmann, M.G. 登録日 1996-05-05 公開日 1996-11-08 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural analysis of Sindbis virus capsid mutants involving assembly and catalysis. J.Mol.Biol., 262, 1996
1KXD	SINDBIS VIRUS CAPSID (N222L MUTANT), TETRAGONAL CRYSTAL FORM 分子名称: SINDBIS VIRUS CAPSID PROTEIN 著者 Choi, H.-K, Rossmann, M.G. 登録日 1996-05-05 公開日 1996-11-08 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural analysis of Sindbis virus capsid mutants involving assembly and catalysis. J.Mol.Biol., 262, 1996
8CDG	Crystal structure of human IL-17A cytokine in complex with macrocycle 分子名称: (9~{S},12~{R},19~{S})-9-[[4-[[(2~{S})-2-cyclohexyl-2-(2-phenylethanoylamino)ethanoyl]amino]phenyl]methyl]-12-methyl-7,10,13,21-tetrakis(oxidanylidene)-8,11,14,20-tetrazaspiro[4.17]docosane-19-carboxylic acid, Interleukin-17A 著者 Schulze, M.-S. 登録日 2023-01-30 公開日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Modulation of IL-17 backbone dynamics reduces receptor affinity and reveals a new inhibitory mechanism. Chem Sci, 14, 2023
3QEW	RB69 DNA Polymerase (L561A/S565G/Y567A) Ternary Complex with dDTP Opposite dT 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ... 著者 Xia, S, Konigsberg, W.H, Wang, J. 登録日 2011-01-20 公開日 2012-01-25 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Hydrogen-Bonding Capability of Difluorotoluene Nucleoside in Replication Complexes To be Published
7WF7	Cryo-EM of Sphingosine 1-phosphate receptor 1 / Gi complex bound to S1P 分子名称: (2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 He, Y, Xu, Z. 登録日 2021-12-26 公開日 2022-01-05 最終更新日 2022-03-16 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structural basis of sphingosine-1-phosphate receptor 1 activation and biased agonism. Nat.Chem.Biol., 18, 2022
1KXB	SINDBIS VIRUS CAPSID (S215A MUTANT), TETRAGONAL CRYSTAL FORM 分子名称: SINDBIS VIRUS CAPSID PROTEIN 著者 Choi, H.-K, Rossmann, M.G. 登録日 1996-05-05 公開日 1996-11-08 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural analysis of Sindbis virus capsid mutants involving assembly and catalysis. J.Mol.Biol., 262, 1996
1KXE	SINDBIS VIRUS CAPSID (Y180S, E183G DOUBLE MUTANT), TETRAGONAL CRYSTAL FORM 分子名称: SINDBIS VIRUS CAPSID PROTEIN 著者 Choi, H.-K, Rossmann, M.G. 登録日 1996-05-05 公開日 1996-11-08 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural analysis of Sindbis virus capsid mutants involving assembly and catalysis. J.Mol.Biol., 262, 1996
3QET	RB69 DNA Polymerase (L561A/S565G/Y567A) Ternary Complex with dTTP Opposite dT 分子名称: CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*CP*AP*TP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), ... 著者 Xia, S, Konigsberg, W.H, Wang, J. 登録日 2011-01-20 公開日 2012-01-25 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 Hydrogen-Bonding Capability of Difluorotoluene Nucleoside in Replication Complexes To be Published
3QEV	RB69 DNA Polymerase (L561A/S565G/Y567A) Ternary Complex with dCTP Opposite dT 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ... 著者 Xia, S, Konigsberg, W.H, Wang, J. 登録日 2011-01-20 公開日 2012-01-25 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Hydrogen-Bonding Capability of Difluorotoluene Nucleoside in Replication Complexes To be Published
8PYW	Crystal structure of the human Nucleoside-diphosphate kinase B domain bound to compound diphosphate form of AT-9052-Sp. 分子名称: GLYCEROL, Nucleoside diphosphate kinase B, [[(2R,3R,4R,5R)-5-(2-azanyl-6-oxidanylidene-1H-purin-9-yl)-4-fluoranyl-4-methyl-3-oxidanyl-oxolan-2-yl]methoxy-sulfanyl-phosphoryl] dihydrogen phosphate 著者 Feracci, M, Chazot, A. 登録日 2023-07-26 公開日 2023-12-27 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.553 Å) 主引用文献 An exonuclease-resistant chain-terminating nucleotide analogue targeting the SARS-CoV-2 replicase complex. Nucleic Acids Res., 52, 2024
3TNP	Structure and Allostery of the PKA RIIb Tetrameric Holoenzyme 分子名称: cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase type II-beta regulatory subunit 著者 Zhang, P, Smith-Nguyen, E.V, Keshwani, M.M, Deal, M.S, Kornev, A.P, Taylor, S.S. 登録日 2011-09-01 公開日 2012-02-01 最終更新日 2013-02-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure and allostery of the PKA RIIbeta tetrameric holoenzyme Science, 335, 2012
4J4L	Modular evolution and design of the protein binding interface 分子名称: Interleukin-6, Internalin B,REPEAT MODULES,Variable lymphocyte receptor B 著者 Cheong, H.K, Kim, H.J. 登録日 2013-02-07 公開日 2014-02-12 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Modular evolution and design of the protein binding interface To be Published
8GF8	Cryo-EM structure of human TRPV1 in cNW11 nanodisc and soybean lipids 分子名称: (2R)-3-{[(R)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctadecanoate, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, ... 著者 Neuberger, A, Nadezhdin, K.D, Sobolevsky, A.I. 登録日 2023-03-07 公開日 2023-05-10 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Human TRPV1 structure and inhibition by the analgesic SB-366791. Nat Commun, 14, 2023
8GF9	Cryo-EM structure of human TRPV1 in cNW11 nanodisc and POPC:POPE:POPG lipids 分子名称: (2R)-3-{[(R)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctadecanoate, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, ... 著者 Neuberger, A, Nadezhdin, K.D, Sobolevsky, A.I. 登録日 2023-03-07 公開日 2023-05-10 実験手法 ELECTRON MICROSCOPY (2.58 Å) 主引用文献 Human TRPV1 structure and inhibition by the analgesic SB-366791. Nat Commun, 14, 2023
8GFA	Cryo-EM structure of human TRPV1 in complex with the analgesic drug SB-366791 分子名称: (2E)-3-(4-chlorophenyl)-N-(3-methoxyphenyl)prop-2-enamide, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, ... 著者 Neuberger, A, Nadezhdin, K.D, Sobolevsky, A.I. 登録日 2023-03-07 公開日 2023-05-10 実験手法 ELECTRON MICROSCOPY (2.29 Å) 主引用文献 Human TRPV1 structure and inhibition by the analgesic SB-366791. Nat Commun, 14, 2023
4BBL	Cryo-electron microscopy reconstruction of the helical part of influenza A virus ribonucleoprotein isolated from virions. 分子名称: NUCLEOPROTEIN, RNA 著者 Arranz, R, Coloma, R, Chichon, F.J, Conesa, J.J, Carrascosa, J.L, Valpuesta, J.M, Ortin, J, Martin-Benito, J. 登録日 2012-09-26 公開日 2012-12-05 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (18 Å) 主引用文献 The Structure of Native Influenza Virion Ribonucleoproteins Science, 338, 2012
8GCR	HPV16 E6-E6AP-p53 complex 分子名称: Cellular tumor antigen p53, Maltose/maltodextrin-binding periplasmic protein,Protein E6, Ubiquitin-protein ligase E3A, ... 著者 Bratkowski, M.A, Wang, J.C.K, Hao, Q, Nile, A.H. 登録日 2023-03-02 公開日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.38 Å) 主引用文献 Structure of the p53 degradation complex from HPV16. Nat Commun, 15, 2024

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