4O22

Binary complex of metal-free PKAc with SP20.

Summary for 4O22

• Entry DOI: 10.2210/pdb4o22/pdb
• Related: 4O21
• Descriptor: cAMP-dependent protein kinase catalytic subunit alpha., Phosphorylated peptide pSP20. (3 entities in total)
• Functional Keywords: ser/thr kinase, phosphoryl transfer, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Mus musculus (mouse); More
• Cellular location: Cytoplasm. Isoform 2: Cell projection, cilium, flagellum (By similarity): P05132
• Total number of polymer chains: 2
• Total formula weight: 42434.17

Authors

Das, A.,Kovalevsky, A.Y.,Gerlits, O.,Langan, P.,Heller, W.T.,Keshwani, M.,Taylor, S.S. (deposition date: 2013-12-16, release date: 2014-05-28)

• Primary citation: Gerlits, O.,Das, A.,Keshwani, M.M.,Taylor, S.,Waltman, M.J.,Langan, P.,Heller, W.T.,Kovalevsky, A.; Metal-Free cAMP-Dependent Protein Kinase Can Catalyze Phosphoryl Transfer.; Biochemistry, 53:3179-3186, 2014; PubMed: 24786636; DOI: 10.1021/bi5000965

Experimental method

X-RAY DIFFRACTION (1.7 Å)