4O22
Binary complex of metal-free PKAc with SP20.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | cAMP-dependent protein kinase catalytic subunit alpha. | polymer | 342 | 40234.8 | 1 | UniProt (P05132) Pfam (PF00069) In PDB | Mus musculus (mouse) | PKA C-alpha |
2 | S | Phosphorylated peptide pSP20. | polymer | 20 | 2199.4 | 1 | UniProt (P61925) In PDB | Homo sapiens (human) | PKI-alpha, cAMP-dependent protein kinase inhibitor alpha, cAMP-dependent protein kinase inhibitor, muscle/brain isoform |
3 | water | water | 18.0 | 271 | Chemie (HOH) |
Sequence modifications
A: 15 - 350 (UniProt: P05132)
S: 605 - 624 (UniProt: P61925)
PDB | External Database | Details |
---|---|---|
His 9 | - | EXPRESSION TAG |
His 10 | - | EXPRESSION TAG |
His 11 | - | EXPRESSION TAG |
His 12 | - | EXPRESSION TAG |
His 13 | - | EXPRESSION TAG |
His 14 | - | EXPRESSION TAG |
PDB | External Database | Details |
---|---|---|
Ala 620 | Asn 21 | ENGINEERED MUTATION |
Ser 621 | Ala 22 | ENGINEERED MUTATION |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 42434.2 | |
All* | Total formula weight | 42434.2 |