PDB: 19228 件ウェブページステータス検索Chemie searchBIRD

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3O95	Crystal Structure of Human DPP4 Bound to TAK-100 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Yano, J.K, Aertgeerts, K. 登録日 2010-08-03 公開日 2011-01-26 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Discovery of a 3-Pyridylacetic Acid Derivative (TAK-100) as a Potent, Selective and Orally Active Dipeptidyl Peptidase IV (DPP-4) Inhibitor. J.Med.Chem., 53, 2011
8D7M	Human Casein kinase 1 delta in complex with phosphorylated human PERIOD2 FASP peptide 分子名称: Casein kinase I isoform delta, Period circadian protein homolog 2 peptide 著者 Philpott, J.M, Freeberg, A.M, Tripathi, S.M, Partch, C.L. 登録日 2022-06-07 公開日 2023-05-17 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 PERIOD phosphorylation leads to feedback inhibition of CK1 activity to control circadian period. Mol.Cell, 83, 2023
8D7O	Human Casein kinase 1 delta in complex with phosphorylated human PERIOD2 FASP peptide 分子名称: Casein kinase I isoform delta, Period circadian protein homolog 2 peptide 著者 Philpott, J.M, Freeberg, A.M, Tripathi, S.M, Partch, C.L. 登録日 2022-06-07 公開日 2023-05-17 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 PERIOD phosphorylation leads to feedback inhibition of CK1 activity to control circadian period. Mol.Cell, 83, 2023
3B8U	Crystal structure of Escherichia coli alaine racemase mutant E221A 分子名称: Alanine racemase, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION 著者 Wu, D, Hu, T, Zhang, L, Jiang, H, Shen, X. 登録日 2007-11-02 公開日 2008-07-08 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Residues Asp164 and Glu165 at the substrate entryway function potently in substrate orientation of alanine racemase from E. coli: Enzymatic characterization with crystal structure analysis Protein Sci., 17, 2008
8D7P	Human Casein kinase 1 delta in complex with phosphorylated Drosophila PERIOD peptide 分子名称: Casein kinase I isoform delta, Period circadian protein peptide 著者 Philpott, J.M, Freeberg, A.M, Tripathi, S.M, Partch, C.L. 登録日 2022-06-07 公開日 2023-05-17 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 PERIOD phosphorylation leads to feedback inhibition of CK1 activity to control circadian period. Mol.Cell, 83, 2023
8D7N	Human Casein kinase 1 delta in complex with phosphorylated human PERIOD2 FASP peptide 分子名称: Casein kinase I isoform delta, Period circadian protein homolog 2 peptide 著者 Philpott, J.M, Freeberg, A.M, Tripathi, S.M, Partch, C.L. 登録日 2022-06-07 公開日 2023-05-17 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 PERIOD phosphorylation leads to feedback inhibition of CK1 activity to control circadian period. Mol.Cell, 83, 2023
2YCL	complete structure of the corrinoid,iron-sulfur protein including the N-terminal domain with a 4Fe-4S cluster 分子名称: CARBON MONOXIDE DEHYDROGENASE CORRINOID/IRON-SULFUR PROTEIN, GAMMA SUBUNIT, CO DEHYDROGENASE/ACETYL-COA SYNTHASE, ... 著者 Goetzl, S, Jeoung, J.H, Hennig, S.E, Dobbek, H. 登録日 2011-03-16 公開日 2011-06-08 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural Basis for Electron and Methyl-Group Transfer in a Methyltransferase System Operating in the Reductive Acetyl-Coa Pathway J.Mol.Biol., 411, 2011
3B0H	Assimilatory nitrite reductase (Nii4) from tobbaco root 分子名称: CHLORIDE ION, IRON/SULFUR CLUSTER, Nitrite reductase, ... 著者 Nakano, S, Takahashi, M, Sakamoto, A, Morikawa, H, Katayanagi, K. 登録日 2011-06-09 公開日 2012-02-22 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.306 Å) 主引用文献 Structure-function relationship of assimilatory nitrite reductases from the leaf and root of tobacco based on high resolution structures Protein Sci., 21, 2012
3B2I	Iodide derivative of human LFABP 分子名称: Fatty acid-binding protein, liver, IODIDE ION, ... 著者 Sharma, A, Yogavel, M, Sharma, A. 登録日 2011-08-03 公開日 2012-07-11 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Utility of anion and cation combinations for phasing of protein structures. J.Struct.Funct.Genom., 13, 2012
3BIX	Crystal structure of the extracellular esterase domain of Neuroligin-1 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, NICKEL (II) ION, ... 著者 Arac, D, Boucard, A.A, Ozkan, E, Strop, P, Newell, E, Sudhof, T.C, Brunger, A.T. 登録日 2007-12-01 公開日 2007-12-18 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structures of Neuroligin-1 and the Neuroligin-1/Neurexin-1beta Complex Reveal Specific Protein-Protein and Protein-Ca(2+) Interactions. Neuron, 56, 2007
3B0J	M175E mutant of assimilatory nitrite reductase (Nii3) from tobbaco leaf 分子名称: CHLORIDE ION, IRON/SULFUR CLUSTER, Nitrite reductase, ... 著者 Nakano, S, Takahashi, M, Sakamoto, A, Morikawa, H, Katayanagi, K. 登録日 2011-06-10 公開日 2012-02-22 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structure-function relationship of assimilatory nitrite reductases from the leaf and root of tobacco based on high resolution structures Protein Sci., 21, 2012
3B2J	Iodide derivative of human LFABP 分子名称: Fatty acid-binding protein, liver, IODIDE ION, ... 著者 Sharma, A, Yogavel, M, Sharma, A. 登録日 2011-08-03 公開日 2012-06-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Utility of anion and cation combinations for phasing of protein structures. J.Struct.Funct.Genom., 13, 2012
3B6Q	Crystal Structure of the GLUR2 Ligand Binding Core (S1S2J) Mutant T686A in Complex with Glutamate at 2.0 Resolution 分子名称: GLUTAMIC ACID, Glutamate receptor 2, SULFATE ION 著者 Cho, Y, Lolis, E, Howe, J.R. 登録日 2007-10-29 公開日 2008-02-05 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural and single-channel results indicate that the rates of ligand binding domain closing and opening directly impact AMPA receptor gating. J.Neurosci., 28, 2008
3BFU	Structure of the ligand-binding core of GluR2 in complex with the agonist (R)-TDPA at 1.95 A resolution 分子名称: (2R)-2-amino-3-(4-hydroxy-1,2,5-thiadiazol-3-yl)propanoic acid, Glutamate receptor 2 著者 Beich-Frandsen, M, Mirza, O, Vestergaard, B, Gajhede, M, Kastrup, J.S. 登録日 2007-11-23 公開日 2008-10-14 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structures of the ligand-binding core of iGluR2 in complex with the agonists (R)- and (S)-2-amino-3-(4-hydroxy-1,2,5-thiadiazol-3-yl)propionic acid explain their unusual equipotency. J.Med.Chem., 51, 2008
2YCJ	methyltransferase bound with methyltetrahydrofolate 分子名称: 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID, 5-METHYLTETRAHYDROFOLATE CORRINOID/IRON SULFUR PROTEIN METHYLTRANSFERASE, GLYCEROL, ... 著者 Goetzl, S, Jeoung, J.-H, Hennig, S.E, Dobbek, H. 登録日 2011-03-16 公開日 2011-06-08 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Structural Basis for Electron and Methyl-Group Transfer in a Methyltransferase System Operating in the Reductive Acetyl-Coa Pathway J.Mol.Biol., 411, 2011
4NXP	Crystal Structure of Free T-cell Lymphoma Invasion and Metastasis-1 PDZ Domain Quadruple Mutant (QM) 分子名称: T-lymphoma invasion and metastasis-inducing protein 1 著者 Liu, X, Speckhard, D.C, Shepherd, T.R, Hengel, S.R, Fuentes, E.J. 登録日 2013-12-09 公開日 2015-05-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Distinct Roles for Conformational Dynamics in Protein-Ligand Interactions. Structure, 24, 2016
3B6W	Crystal Structure of the GLUR2 Ligand Binding Core (S1S2J) T686S Mutant in Complex with Glutamate at 1.7 Resolution 分子名称: GLUTAMIC ACID, Glutamate receptor 2, SULFATE ION 著者 Cho, Y, Lolis, E, Howe, J.R. 登録日 2007-10-29 公開日 2008-02-05 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural and single-channel results indicate that the rates of ligand binding domain closing and opening directly impact AMPA receptor gating. J.Neurosci., 28, 2008
8DGO	Growth Factor Receptor-Bound Protein 2 (Grb2) bound to phosphorylated PEAK3 (pY24) peptide 分子名称: Growth factor receptor bound protein 2, Phosphorylated PEAK3 (pY24) peptide 著者 Roy, M.J, Hardy, J.M, Lucet, I.S. 登録日 2022-06-24 公開日 2023-06-07 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural mapping of PEAK pseudokinase interactions identifies 14-3-3 as a molecular switch for PEAK3 signaling. Nat Commun, 14, 2023
3BOK	Structure of the C. botulinum neurotoxin serotype A apo-enzyme 分子名称: Neurotoxin A 著者 Silvaggi, N.R, Allen, K.N. 登録日 2007-12-17 公開日 2008-05-20 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Catalytic features of the botulinum neurotoxin A light chain revealed by high resolution structure of an inhibitory peptide complex. Biochemistry, 47, 2008
3OPM	Crystal Structure of Human DPP4 Bound to TAK-294 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-{[3-(aminomethyl)-2-(2-methylpropyl)-1-oxo-4-phenyl-1,2-dihydroisoquinolin-6-yl]oxy}acetamide, ... 著者 Yano, J.K, Aertgeerts, K. 登録日 2010-09-01 公開日 2011-10-19 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.72 Å) 主引用文献 Identification of 3-aminomethyl-1,2-dihydro-4-phenyl-1-isoquinolones: a new class of potent, selective, and orally active non-peptide dipeptidyl peptidase IV inhibitors that form a unique interaction with Lys554. Bioorg.Med.Chem., 19, 2011
2YCI	methyltransferase native 分子名称: 5-METHYLTETRAHYDROFOLATE CORRINOID/IRON SULFUR PROTEIN METHYLTRANSFERASE, SULFATE ION 著者 Goetzl, S, Jeoung, J.H, Hennig, S.E, Dobbek, H. 登録日 2011-03-16 公開日 2011-06-08 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Structural Basis for Electron and Methyl-Group Transfer in a Methyltransferase System Operating in the Reductive Acetyl-Coa Pathway J.Mol.Biol., 411, 2011
3BWJ	Complex of PKA with the bisubstrate protein kinase inhibitor lead compound Arc-1034 分子名称: (2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-(6-{[(1R)-4-carbamimidamido-1-{[(1R)-4-carbamimidamido-1-carbamoylbutyl]carbamoyl}butyl]amino}-6-oxohexyl)-3,4-dihydroxytetrahydrofuran-2-carboxamide, cAMP-dependent protein kinase, alpha-catalytic subunit 著者 Lavogina, D, Koenig, N, Uri, A, Bossemeyer, D. 登録日 2008-01-09 公開日 2009-02-03 最終更新日 2019-09-04 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural analysis of ARC-type inhibitor (ARC-1034) binding to protein kinase A catalytic subunit and rational design of bisubstrate analogue inhibitors of basophilic protein kinases. J.Med.Chem., 52, 2009
7XS7	structure of a membrane-integrated glycosyltransferase 分子名称: (19R,22S)-25-amino-22-hydroxy-22-oxido-16-oxo-17,21,23-trioxa-22lambda~5~-phosphapentacosan-19-yl (9Z)-hexadec-9-enoate, Chitin synthase 1, DODECANE, ... 著者 Wu, Y.N, Zhang, M, Yang, Y.Z, Ding, X.Y, Liu, X.T, Zhang, M.J, Yu, H.J. 登録日 2022-05-13 公開日 2023-05-17 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 structure of a membrane-integrated glycosyltransferase with inhibitor To Be Published
7XS6	structure of a membrane-integrated glycosyltransferase with inhibitor 分子名称: (19R,22S)-25-amino-22-hydroxy-22-oxido-16-oxo-17,21,23-trioxa-22lambda~5~-phosphapentacosan-19-yl (9Z)-hexadec-9-enoate, (2S)-{[(2S,3S,4S)-2-amino-4-hydroxy-4-(5-hydroxypyridin-2-yl)-3-methylbutanoyl]amino}[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxyoxolan-2-yl]acetic acid (non-preferred name), Chitin synthase 1, ... 著者 Wu, Y.N, Zhang, M, Yang, Y.Z, Ding, X.Y, Liu, X.T, Zhang, M.J, Yu, H.J. 登録日 2022-05-12 公開日 2023-05-17 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 structure of a membrane-integrated glycosyltransferase with inhibitor To Be Published
3C9L	Structure of ground-state bovine rhodospin in a hexagonal crystal form 分子名称: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, ACETYL GROUP, DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, ... 著者 Stenkamp, R.E. 登録日 2008-02-16 公開日 2008-08-05 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.646 Å) 主引用文献 Alternative models for two crystal structures of bovine rhodopsin. Acta Crystallogr.,Sect.D, 64, 2008

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