7XS6

structure of a membrane-integrated glycosyltransferase with inhibitor

Summary for 7XS6

• Entry DOI: 10.2210/pdb7xs6/pdb
• EMDB information: 33422
• Descriptor: Chitin synthase 1, TETRADECANE, DODECANE, ... (6 entities in total)
• Functional Keywords: membrane protein, glycosyltransferase, transferase
• Biological source: Saccharomyces cerevisiae (baker's yeast)
• Total number of polymer chains: 2
• Total formula weight: 268653.43

Authors

Wu, Y.N.,Zhang, M.,Yang, Y.Z.,Ding, X.Y.,Liu, X.T.,Zhang, M.J.,Yu, H.J. (deposition date: 2022-05-12, release date: 2023-05-17, Last modification date: 2025-06-18)

• Primary citation: Wu, Y.,Zhang, M.,Yang, Y.,Ding, X.,Yang, P.,Huang, K.,Hu, X.,Zhang, M.,Liu, X.,Yu, H.; Structures and mechanism of chitin synthase and its inhibition by antifungal drug Nikkomycin Z.; Cell Discov, 8:129-129, 2022; PubMed: 36473834; DOI: 10.1038/s41421-022-00495-y

Experimental method

ELECTRON MICROSCOPY (2.9 Å)