PDB: 17012 件ウェブページステータス検索Chemie searchBIRD

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3AWD	Crystal structure of gox2181 分子名称: CADMIUM ION, MAGNESIUM ION, Putative polyol dehydrogenase 著者 Adam Yuan, Y, Yuan, Z. 登録日 2011-03-18 公開日 2012-02-01 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Biochemical and structural analysis of Gox2181, a new member of the SDR superfamily from Gluconobacter oxydans. Biochem.Biophys.Res.Commun., 415, 2011
4BXK	Crystal structure of the Angiotensin-1 converting enzyme N-domain in complex with a domain-specific inhibitor 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANGIOTENSIN-CONVERTING ENZYME, ... 著者 Douglas, R.G, Sharma, R.K, Masuyer, G, Lubbe, L, Zamora, I, Acharya, K.R, Chibale, K, Sturrock, E.D. 登録日 2013-07-12 公開日 2013-09-18 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Fragment-Based Design for the Development of N-Domain Selective Angiotensin-1 Converting Enzyme Inhibitors Clin.Sci., 126, 2014
3B4F	Carbonic anhydrase inhibitors. Interaction of 2-(hydrazinocarbonyl)-3-phenyl-1H-indole-5-sulfonamide with twelve mammalian isoforms: kinetic and X-Ray crystallographic studies 分子名称: 2-(hydrazinocarbonyl)-3-phenyl-1H-indole-5-sulfonamide, Carbonic anhydrase 2, MERCURY (II) ION, ... 著者 Guzel, o, Temperini, c, Innocenti, a, Scozzafava, A, Salman, a, Supuran, c.t. 登録日 2007-10-24 公開日 2008-01-22 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Carbonic anhydrase inhibitors. Interaction of 2-(hydrazinocarbonyl)-3-phenyl-1H-indole-5-sulfonamide with 12 mammalian isoforms: kinetic and X-ray crystallographic studies. Bioorg.Med.Chem.Lett., 18, 2008
3B7A	Complex of S52A Substituted Droposphila LUSH protein with Ethanol 分子名称: ACETATE ION, ETHANOL, General odorant-binding protein lush 著者 Jones, D.N.M, Thode, A.B. 登録日 2007-10-30 公開日 2008-02-05 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The role of multiple hydrogen-bonding groups in specific alcohol binding sites in proteins: insights from structural studies of LUSH. J.Mol.Biol., 376, 2008
4BNE	Pacsin2 Interacts with Membranes and Actin-Filaments 分子名称: PROTEIN KINASE C AND CASEIN KINASE SUBSTRATE IN NEURONS PROTEIN 2, SULFATE ION, TRIETHYLENE GLYCOL 著者 Kostan, J, Salzer, U, Orlova, A, Toeroe, I, Hodnik, V, Schreiner, C, Merilainen, J, Nikki, M, Virtanen, I, Lehto, V.-P, Anderluh, G, Egelman, E.H, Djinovic-Carugo, K. 登録日 2013-05-15 公開日 2014-05-14 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.57 Å) 主引用文献 Direct Interaction of Actin Filaments with F-Bar Protein Pacsin2. Embo Rep., 15, 2014
4CAM	Structure of rat neuronal nitric oxide synthase heme domain in complex with 7-((3-Fluorophenethylamino)methyl)quinolin-2-amine 分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, 7-[[2-(3-fluorophenyl)ethylamino]methyl]quinolin-2-amine, ACETATE ION, ... 著者 Li, H, Poulos, T.L. 登録日 2013-10-08 公開日 2014-02-19 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Simplified 2-Aminoquinoline-Based Scaffold for Potent and Selective Neuronal Nitric Oxide Synthase Inhibition. J.Med.Chem., 57, 2014
4BQN	Structural insights into WcbI, a novel polysaccharide biosynthesis enzyme. Native protein. 分子名称: CAPSULAR POLYSACCHARIDE BIOSYNTHESIS PROTEIN, CHLORIDE ION, COENZYME A, ... 著者 Vivoli, M, Ayres, E, Isupov, M.N, Harmer, N.J. 登録日 2013-05-31 公開日 2013-11-06 最終更新日 2014-08-13 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 Structural Insights Into Wcbi, a Novel Polysaccharide-Biosynthesis Enzyme. Iucrj, 1, 2014
4CAN	Structure of rat neuronal nitric oxide synthase heme domain in complex with 7-(2-(3-Fluorobenzylamino)ethyl)quinolin-2-amine 分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, 7-{2-[(3-fluorobenzyl)amino]ethyl}quinolin-2-amine, ACETATE ION, ... 著者 Li, H, Poulos, T.L. 登録日 2013-10-08 公開日 2014-02-19 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Simplified 2-Aminoquinoline-Based Scaffold for Potent and Selective Neuronal Nitric Oxide Synthase Inhibition. J.Med.Chem., 57, 2014
3COC	Crystal Structure of D115A mutant of Bacteriorhodopsin 分子名称: Bacteriorhodopsin, RETINAL 著者 Joh, N.H, Faham, S, Bowie, J.U. 登録日 2008-03-27 公開日 2008-04-08 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Modest stabilization by most hydrogen-bonded side-chain interactions in membrane proteins. Nature, 453, 2008
3D5U	Crystal structure of a wildtype Polo-like kinase 1 (Plk1) catalytic domain. 分子名称: Polo-like kinase 1 著者 Elling, R.A, Fucini, R.V, Romanowski, M.J. 登録日 2008-05-17 公開日 2008-08-26 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structures of the wild-type and activated catalytic domains of Brachydanio rerio Polo-like kinase 1 (Plk1): changes in the active-site conformation and interactions with ligands. Acta Crystallogr.,Sect.D, 64, 2008
2E2Z	Solution NMR structure of yeast Tim15, co-chaperone of mitochondrial Hsp70 分子名称: Tim15, ZINC ION 著者 Momose, T, Ohshima, C, Maeda, M, Endo, T. 登録日 2006-11-19 公開日 2007-10-09 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Structural basis of functional cooperation of Tim15/Zim17 with yeast mitochondrial Hsp70 Embo Rep., 8, 2007
2DS2	Crystal structure of mabinlin II 分子名称: ACETIC ACID, Sweet protein mabinlin-2 chain A, Sweet protein mabinlin-2 chain B 著者 Li, D.F, Zhu, D.Y, Wang, D.C. 登録日 2006-06-19 公開日 2007-06-12 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of Mabinlin II: a novel structural type of sweet proteins and the main structural basis for its sweetness. J.Struct.Biol., 162, 2008
3CUK	Crystal structure of human D-amino acid oxidase: bound to an inhibitor 分子名称: 4H-furo[3,2-b]pyrrole-5-carboxylic acid, D-amino-acid oxidase, FLAVIN-ADENINE DINUCLEOTIDE 著者 Prasad, S, Munshi, S. 登録日 2008-04-16 公開日 2008-07-22 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 The discovery of fused pyrrole carboxylic acids as novel, potent D-amino acid oxidase (DAO) inhibitors. Bioorg.Med.Chem.Lett., 18, 2008
3CS8	Structural and Biochemical Basis for the Binding Selectivity of PPARg to PGC-1a 分子名称: 2,4-THIAZOLIDIINEDIONE, 5-[[4-[2-(METHYL-2-PYRIDINYLAMINO)ETHOXY]PHENYL]METHYL]-(9CL), PGC-1alfa peptide, ... 著者 Li, Y, Martynowski, D. 登録日 2008-04-09 公開日 2008-06-03 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural and biochemical basis for the binding selectivity of peroxisome proliferator-activated receptor gamma to PGC-1alpha. J.Biol.Chem., 283, 2008
2FLE	Structural analysis of asymmetric inhibitor bound to the HIV-1 Protease V82A mutant 分子名称: (2S,2'S)-N,N'-[(2S,3S,4S,5S)-1-CYCLOHEXYL-3,4-DIHYDROXY-6-PHENYLHEXANE-2,5-DIYL]BIS[3-METHYL-2-({[METHYL(PYRIDIN-2-YLMETHYL)AMINO]CARBONYL}AMINO)BUTANAMIDE], GLYCEROL, pol protein 著者 Clemente, J.C, Robbins, A, Dunn, B.M, Sussman, F. 登録日 2006-01-05 公開日 2007-01-16 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Design, synthesis, evaluation, and crystallographic-based structural studies of HIV-1 protease inhibitors with reduced response to the V82A mutation. J.Med.Chem., 51, 2008
2FKG	The Crystal Structure of Engineered OspA 分子名称: Outer Surface Protein A 著者 Makabe, K, Terechko, V, Gawlak, G, Yan, S, Koide, S. 登録日 2006-01-04 公開日 2006-11-21 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Atomic structures of peptide self-assembly mimics. Proc.Natl.Acad.Sci.Usa, 103, 2006
3D2A	Structure of 1-17A4, a thermostable mutant of Bacillus subtilis lipase obtained through directed evolution 分子名称: Lipase 著者 Sankaranarayanan, R, Kamal, M.Z. 登録日 2008-05-08 公開日 2008-06-03 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Thermostable Bacillus subtilis lipases: in vitro evolution and structural insight J.Mol.Biol., 381, 2008
2GAB	Human Transthyretin (TTR) Complexed with Hydroxylated polychlorinated Biphenyl-4-hydroxy-3,3',5,4'-tetrachlorobiphenyl 分子名称: 3,3',4',5-TETRACHLOROBIPHENYL-4-OL, Transthyretin 著者 Palaninathan, S.K, Smith, C, Safe, S.H, Kelly, J.W, Sacchettini, J.C. 登録日 2006-03-08 公開日 2006-03-21 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Hydroxylated polychlorinated biphenyls selectively bind transthyretin in blood and inhibit amyloidogenesis: rationalizing rodent PCB toxicity Chem.Biol., 11, 2004
2FZM	Structure of the E. coli PutA proline dehydrogenase domain reduced by dithionite and complexed with SO2 分子名称: Bifunctional protein putA, Proline dehydrogenase (EC 1.5.99.8) (Proline oxidase), FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Tanner, J.J. 登録日 2006-02-09 公開日 2007-04-03 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Redox-induced changes in flavin structure and roles of flavin N(5) and the ribityl 2'-OH group in regulating PutA--membrane binding. Biochemistry, 46, 2007
5A7C	Crystal structure of the second bromodomain of human BRD3 in complex with compound 分子名称: 1,2-ETHANEDIOL, BROMODOMAIN-CONTAINING PROTEIN 3, N-(6-ACETAMIDOHEXYL)ACETAMIDE 著者 Welin, M, Kimbung, R, Diehl, C, Hakansson, M, Logan, D.T, Walse, B. 登録日 2015-07-03 公開日 2016-03-16 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Cancer Differentiating Agent Hexamethylene Bisacetamide Inhibits Bet Bromodomain Proteins. Cancer Res., 76, 2016
5AFD	Native structure of N-acetylneuramininate lyase (sialic acid aldolase) from Aliivibrio salmonicida 分子名称: 1,2-ETHANEDIOL, GLYCEROL, N-ACETYLNEURAMINATE LYASE 著者 Gurung, M.K, Altermark, B, Rader, I.L.U, Helland, R, Smalas, A.O. 登録日 2015-01-21 公開日 2016-03-02 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Features and structure of a cold active N-acetylneuraminate lyase. Plos One, 14, 2019
5A5Z	Approved Drugs Containing Thiols as Inhibitors of Metallo-beta- lactamases: Strategy To Combat Multidrug-Resistant Bacteria 分子名称: BETA-LACTAMASE NDM-1, TIOPRONIN, ZINC ION 著者 Klingler, F.M, Wichelhaus, T.A, Frank, D, Cuesta-Bernal, J, El-Delik, J, Mueller, H.F, Sjuts, H, Goettig, S, Koenigs, A, Pogoryelov, D, Proschak, E. 登録日 2015-06-23 公開日 2015-07-08 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Approved Drugs Containing Thiols as Inhibitors of Metallo-beta-lactamases: Strategy To Combat Multidrug-Resistant Bacteria. J. Med. Chem., 58, 2015
4UJ5	Crystal structure of human Rab11-Rabin8-FIP3 分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, RAB-3A-INTERACTING PROTEIN, ... 著者 Vetter, M, Lorentzen, E. 登録日 2015-04-08 公開日 2015-08-12 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.604 Å) 主引用文献 Structure of Rab11-Fip3-Rabin8 Reveals Simultaneous Binding of Fip3 and Rabin8 Effectors to Rab11. Nat.Struct.Mol.Biol., 22, 2015
5AD8	Structure of rat neuronal nitric oxide synthase heme domain in complex with 7-((3-Aminomethyl)phenoxy)methyl)quinolin-2-amine 分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, 7-[[3-(aminomethyl)phenoxy]methyl]quinolin-2-amine, ACETATE ION, ... 著者 Li, H, Poulos, T.L. 登録日 2015-08-20 公開日 2015-10-28 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.905 Å) 主引用文献 Phenyl Ether- and Aniline-Containing 2-Aminoquinolines as Potent and Selective Inhibitors of Neuronal Nitric Oxide Synthase. J.Med.Chem., 58, 2015
5ADA	Structure of rat neuronal nitric oxide synthase heme domain in complex with 7-(((3-((Dimethylamino)methyl)phenyl)amino)methyl) quinolin-2-amine 分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, 7-[[[3-[(dimethylamino)methyl]phenyl]amino]methyl]quinolin-2-amine, ACETATE ION, ... 著者 Li, H, Poulos, T.L. 登録日 2015-08-20 公開日 2015-10-28 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Phenyl Ether- and Aniline-Containing 2-Aminoquinolines as Potent and Selective Inhibitors of Neuronal Nitric Oxide Synthase. J.Med.Chem., 58, 2015

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