4BXK
Crystal structure of the Angiotensin-1 converting enzyme N-domain in complex with a domain-specific inhibitor
Summary for 4BXK
Entry DOI | 10.2210/pdb4bxk/pdb |
Descriptor | ANGIOTENSIN-CONVERTING ENZYME, CHLORIDE ION, TETRAETHYLENE GLYCOL, ... (13 entities in total) |
Functional Keywords | hydrolase, metalloprotease, protease inhibitor |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 2 |
Total formula weight | 150421.73 |
Authors | Douglas, R.G.,Sharma, R.K.,Masuyer, G.,Lubbe, L.,Zamora, I.,Acharya, K.R.,Chibale, K.,Sturrock, E.D. (deposition date: 2013-07-12, release date: 2013-09-18, Last modification date: 2023-12-20) |
Primary citation | Douglas, R.G.,Sharma, R.K.,Masuyer, G.,Lubbe, L.,Zamora, I.,Acharya, K.R.,Chibale, K.,Sturrock, E.D. Fragment-Based Design for the Development of N-Domain Selective Angiotensin-1 Converting Enzyme Inhibitors Clin.Sci., 126:305-, 2014 Cited by PubMed: 24015848DOI: 10.1042/CS20130403 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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