3CUK

Crystal structure of human D-amino acid oxidase: bound to an inhibitor

Summary for 3CUK

Entry DOI	10.2210/pdb3cuk/pdb
Descriptor	D-amino-acid oxidase, FLAVIN-ADENINE DINUCLEOTIDE, 4H-furo[3,2-b]pyrrole-5-carboxylic acid, ... (4 entities in total)
Functional Keywords	oxidoreductase, alpha-beta-alpha motif, flavin containing proteinalpha-beta-alpha motif, flavin containing protein, fad, flavoprotein, peroxisome
Biological source	Homo sapiens
Cellular location	Peroxisome: P14920
Total number of polymer chains	4
Total formula weight	161830.32
Authors	Prasad, S.,Munshi, S. (deposition date: 2008-04-16, release date: 2008-07-22, Last modification date: 2023-08-30)
Primary citation	Sparey, T.,Abeywickrema, P.,Almond, S.,Brandon, N.,Byrne, N.,Campbell, A.,Hutson, P.H.,Jacobson, M.,Jones, B.,Munshi, S.,Pascarella, D.,Pike, A.,Prasad, G.S.,Sachs, N.,Sakatis, M.,Sardana, V.,Venkatraman, S.,Young, M.B. The discovery of fused pyrrole carboxylic acids as novel, potent D-amino acid oxidase (DAO) inhibitors. Bioorg.Med.Chem.Lett., 18:3386-3391, 2008 Cited by PubMed: 18455394 DOI: 10.1016/j.bmcl.2008.04.020 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.49 Å)

Structure validation