PDB: 13422 件ウェブページステータス検索Chemie searchBIRD

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5TXN	STRUCTURE OF Q151M MUTANT HIV-1 REVERSE TRANSCRIPTASE (RT) TERNARY COMPLEX WITH A DOUBLE STRANDED DNA AND AN INCOMING DATP 分子名称: 1,2-ETHANEDIOL, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*(MRG)P*CP*GP*CP*CP*G)-3'), ... 著者 Das, K, Martinez, S.M, Arnold, E. 登録日 2016-11-17 公開日 2017-04-05 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structural Insights into HIV Reverse Transcriptase Mutations Q151M and Q151M Complex That Confer Multinucleoside Drug Resistance. Antimicrob. Agents Chemother., 61, 2017
3JA9	Structure of native human PCNA 分子名称: Proliferating cell nuclear antigen 著者 Lau, W.C.Y, Li, Y, Zhang, Q, Huen, M.S.Y. 登録日 2015-05-19 公開日 2015-12-09 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (22 Å) 主引用文献 Molecular architecture of the Ub-PCNA/Pol eta complex bound to DNA Sci Rep, 5, 2015
1AWC	MOUSE GABP ALPHA/BETA DOMAIN BOUND TO DNA 分子名称: DNA (5'-D(*AP*AP*(BRU)P*GP*AP*CP*CP*GP*GP*AP*AP*GP*TP*AP*(CBR)P*AP*CP*(CBR)P*GP*GP*A)-3'), DNA (5'-D(*TP*TP*CP*CP*GP*GP*(BRU)P*GP*(BRU)P*AP*CP*TP*TP*CP*CP*GP*GP*TP*CP*AP*T)-3'), PROTEIN (GA BINDING PROTEIN ALPHA), ... 著者 Batchelor, A.H, Wolberger, C. 登録日 1997-10-01 公開日 1998-03-18 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 The structure of GABPalpha/beta: an ETS domain- ankyrin repeat heterodimer bound to DNA. Science, 279, 1998
6JWP	crystal structure of EGOC 分子名称: Ego2, GTP-binding protein GTR1, GTP-binding protein GTR2, ... 著者 Zhang, T, Ding, J. 登録日 2019-04-21 公開日 2019-12-11 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural insights into the EGO-TC-mediated membrane tethering of the TORC1-regulatory Rag GTPases. Sci Adv, 5, 2019
2WHX	A second conformation of the NS3 protease-helicase from dengue virus 分子名称: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, MANGANESE (II) ION, ... 著者 Luo, D, Lescar, J. 登録日 2009-05-07 公開日 2010-04-07 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Flexibility between the Protease and Helicase Domains of the Dengue Virus Ns3 Protein Conferred by the Linker Region and its Functional Implications. J.Biol.Chem., 285, 2010
5VFU	Nucleotide-driven Triple-state Remodeling of the AAA-ATPase Channel in the Activated Human 26S Proteasome 分子名称: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ... 著者 Zhu, Y, Wang, W.L, Yu, D, Ouyang, Q, Lu, Y, Mao, Y. 登録日 2017-04-09 公開日 2018-07-18 最終更新日 2021-03-24 実験手法 ELECTRON MICROSCOPY (5.8 Å) 主引用文献 Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome. Nat Commun, 9, 2018
1P5O	Solution Structure of HCV IRES Domain II 分子名称: 77-MER 著者 Lukavsky, P.J, Kim, I, Otto, G.A, Puglisi, J.D. 登録日 2003-04-27 公開日 2003-11-04 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Structure of HCV IRES domain II determined by NMR. Nat.Struct.Biol., 10, 2003
8T2T	Structure of a group II intron ribonucleoprotein in the post-ligation (post-2F) state 分子名称: AMMONIUM ION, Group II intron reverse transcriptase/maturase, MAGNESIUM ION, ... 著者 Xu, L, Liu, T, Chung, K, Pyle, A.M. 登録日 2023-06-06 公開日 2023-11-22 最終更新日 2024-01-03 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structural insights into intron catalysis and dynamics during splicing. Nature, 624, 2023
4M5V	Influenza 2009 H1N1 endonuclease with 100 millimolar calcium 分子名称: CALCIUM ION, Polymerase PA, SULFATE ION 著者 Bauman, J.D, Patel, D, Das, K, Arnold, E. 登録日 2013-08-08 公開日 2013-09-18 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystallographic fragment screening and structure-based optimization yields a new class of influenza endonuclease inhibitors. Acs Chem.Biol., 8, 2013
6W4G	Hepatitis C virus polymerase NS5B with RO inhibitor for SAR studies 分子名称: 5-[[(2~{S})-4-[1,1-bis(oxidanylidene)-1,2-benzothiazol-3-yl]-2-~{tert}-butyl-3-oxidanyl-5-oxidanylidene-2~{H}-pyrrol-1-yl]methyl]-2-fluoranyl-benzenecarbonitrile, NS5B 著者 Harris, S.F. 登録日 2020-03-10 公開日 2020-11-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Identification of Noncompetitive Protein-Ligand Interactions for Structural Optimization. J.Chem.Inf.Model., 60, 2020
4M5O	3-HYDROXY-6-PHENYL-1,2-DIHYDROPYRIDIN-2-ONE bound to influenza 2009 H1N1 endonuclease 分子名称: 1,2-ETHANEDIOL, 3-hydroxy-6-phenylpyridin-2(5H)-one, MANGANESE (II) ION, ... 著者 Bauman, J.D, Patel, D, Das, K, Arnold, E. 登録日 2013-08-08 公開日 2013-09-18 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystallographic fragment screening and structure-based optimization yields a new class of influenza endonuclease inhibitors. Acs Chem.Biol., 8, 2013
1P5P	Solution Structure of HCV IRES Domain II (minimized average structure) 分子名称: 77-MER 著者 Lukavsky, P.J, Kim, I, Otto, G.A, Puglisi, J.D. 登録日 2003-04-27 公開日 2003-11-04 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Structure of HCV IRES domain II determined by NMR. Nat.Struct.Biol., 10, 2003
2W2G	Human SARS coronavirus unique domain 分子名称: NON-STRUCTURAL PROTEIN 3, SULFATE ION 著者 Tan, J, Vonrhein, C, Smart, O.S, Bricogne, G, Bollati, M, Kusov, Y, Hansen, G, Mesters, J.R, Schmidt, C.L, Hilgenfeld, R. 登録日 2008-10-30 公開日 2009-05-26 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 The Sars-Unique Domain (Sud) of Sars Coronavirus Contains Two Macrodomains that Bind G-Quadruplexes. Plos Pathog., 5, 2009
7WJV	Crystal structure of human liver FBPase complexed with an covalent inhibitor 分子名称: 1,2-BENZISOTHIAZOL-3(2H)-ONE 1,1-DIOXIDE, ADENOSINE MONOPHOSPHATE, Fructose-1,6-bisphosphatase 1, ... 著者 Cao, H, Huang, Y, Ren, Y, Wan, J. 登録日 2022-01-08 公開日 2022-07-13 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.724 Å) 主引用文献 N -Acylamino Saccharin as an Emerging Cysteine-Directed Covalent Warhead and Its Application in the Identification of Novel FBPase Inhibitors toward Glucose Reduction. J.Med.Chem., 65, 2022
4M5Q	High-resolution apo influenza 2009 H1N1 endonuclease structure 分子名称: 1,2-ETHANEDIOL, MANGANESE (II) ION, Polymerase PA 著者 Bauman, J.D, Patel, D, Das, K, Arnold, E. 登録日 2013-08-08 公開日 2013-09-18 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.534 Å) 主引用文献 Crystallographic fragment screening and structure-based optimization yields a new class of influenza endonuclease inhibitors. Acs Chem.Biol., 8, 2013
4M4Q	6-(4-fluorophenyl)-3-hydroxy-5-[4-(1H-1,2,3,4-tetrazol-5-yl)phenyl] -1,2-dihydropyridin-2-one bound to influenza 2009 H1N1 endonuclease 分子名称: 6-(4-fluorophenyl)-5-[4-(1H-tetrazol-5-yl)phenyl]pyridine-2,3-diol, MAGNESIUM ION, MANGANESE (II) ION, ... 著者 Bauman, J.D, Patel, D, Das, K, Arnold, E. 登録日 2013-08-07 公開日 2013-09-18 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.502 Å) 主引用文献 Crystallographic fragment screening and structure-based optimization yields a new class of influenza endonuclease inhibitors. Acs Chem.Biol., 8, 2013
1P5M	Solution Structure of HCV IRES Domain IIa 分子名称: 55-MER 著者 Lukavsky, P.J, Kim, I, Otto, G.A, Puglisi, J.D. 登録日 2003-04-27 公開日 2003-11-04 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Structure of HCV IRES domain II determined by NMR. Nat.Struct.Biol., 10, 2003
6O3Y	Crystal structure of yeast Nrd1 CID in complex with Sen1 NIM3 分子名称: CHLORIDE ION, Helicase SEN1, Protein NRD1 著者 Zhang, Y, Tong, L. 登録日 2019-02-27 公開日 2019-06-05 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.799 Å) 主引用文献 Identification of Three Sequence Motifs in the Transcription Termination Factor Sen1 that Mediate Direct Interactions with Nrd1. Structure, 27, 2019
2AGQ	Fidelity of Dpo4: effect of metal ions, nucleotide selection and pyrophosphorolysis 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 5'-D(*GP*GP*CP*TP*AP*CP*AP*GP*GP*AP*CP*TP*(DOC))-3', 5'-D(*TP*CP*AP*TP*GP*AP*GP*TP*CP*CP*TP*GP*TP*AP*GP*CP*C)-3', ... 著者 Ling, H, Yang, W. 登録日 2005-07-27 公開日 2005-09-06 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Fidelity of Dpo4: effect of metal ions, nucleotide selection and pyrophosphorolysis. Embo J., 24, 2005
1AXC	HUMAN PCNA 分子名称: P21/WAF1, PCNA 著者 Gulbis, J.M, Kuriyan, J. 登録日 1997-10-14 公開日 1998-01-28 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure of the C-terminal region of p21(WAF1/CIP1) complexed with human PCNA. Cell(Cambridge,Mass.), 87, 1996
1MIV	Crystal structure of Bacillus stearothermophilus CCA-adding enzyme 分子名称: MAGNESIUM ION, tRNA CCA-adding enzyme 著者 Li, F, Xiong, Y, Wang, J, Cho, H.D, Weiner, A.M, Steitz, T.A. 登録日 2002-08-23 公開日 2002-12-13 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Crystal structures of the Bacillus stearothermophilus CCA-adding enzyme and its complexes with ATP or CTP Cell(Cambridge,Mass.), 111, 2002
3TG5	Structure of SMYD2 in complex with p53 and SAH 分子名称: Cellular tumor antigen p53, GLYCEROL, N-lysine methyltransferase SMYD2, ... 著者 Zhao, K, Wang, L. 登録日 2011-08-17 公開日 2011-08-31 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of human SMYD2 reveals the basis of p53 tumor suppressor methylation J.Biol.Chem., 2011
4M5R	High-resolution influenza 2009 H1N1 endonuclease bound to 4-(1H-IMIDAZOL-1-YL)PHENOL 分子名称: 1,2-ETHANEDIOL, 4-(1H-IMIDAZOL-1-YL)PHENOL, MANGANESE (II) ION, ... 著者 Bauman, J.D, Patel, D, Das, K, Arnold, E. 登録日 2013-08-08 公開日 2013-09-18 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystallographic fragment screening and structure-based optimization yields a new class of influenza endonuclease inhibitors. Acs Chem.Biol., 8, 2013
1MIW	Crystal structure of Bacillus stearothermophilus CCA-adding enzyme in complex with ATP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, tRNA CCA-adding enzyme 著者 Li, F, Xiong, Y, Wang, J, Cho, H.D, Weiner, A.M, Steitz, T.A. 登録日 2002-08-23 公開日 2002-12-13 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal structures of the Bacillus stearothermophilus CCA-adding enzyme and its complexes with ATP or CTP Cell(Cambridge,Mass.), 111, 2002
4JGH	Structure of the SOCS2-Elongin BC complex bound to an N-terminal fragment of Cullin5 分子名称: Cullin-5, Suppressor of cytokine signaling 2, Transcription elongation factor B polypeptide 1, ... 著者 Kim, Y.K, Kwak, M.J, Ku, B, Suh, H.Y, Joo, K, Lee, J, Jung, J.U, Oh, B.H. 登録日 2013-03-01 公開日 2013-08-07 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis of intersubunit recognition in elongin BC-cullin 5-SOCS box ubiquitin-protein ligase complexes. Acta Crystallogr.,Sect.D, 69, 2013

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