PDB: 760 件ウェブページステータス検索Chemie searchBIRD

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7W67	The crystal structure of MLL1 (N3861I/Q3867L/C3882SS)-RBBP5-ASH2L in complex with H3K4me0 peptide 分子名称: Histone H3.3C, Histone-lysine N-methyltransferase 2A, Retinoblastoma-binding protein 5, ... 著者 Zhao, L, Li, Y, Chen, Y. 登録日 2021-12-01 公開日 2022-09-07 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.194 Å) 主引用文献 Structural basis for product specificities of MLL family methyltransferases. Mol.Cell, 82, 2022
6MFB	Crystal structure of 3-hydroxykynurenine transaminase from Aedes aegypti 分子名称: PYRIDOXAL-5'-PHOSPHATE, Serine--pyruvate aminotransferase 著者 Maciel, L.G, Oliveira, A.A, Romao, T.P, Silva Filha, M.H.N.L, dos Anjos, J.V, Soares, T.A, Guido, R.V.C. 登録日 2018-09-10 公開日 2019-09-18 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of 3-hydroxykynurenine transaminase from Aedes aegypti To Be Published
2LXT	Allosteric communication in the KIX domain proceeds through dynamic re-packing of the hydrophobic core 分子名称: CREB-binding protein, Cyclic AMP-responsive element-binding protein 1, Histone-lysine N-methyltransferase MLL 著者 Bruschweiler, S, Schanda, P, Konrat, R, Tollinger, M. 登録日 2012-08-31 公開日 2013-06-12 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Allosteric communication in the KIX domain proceeds through dynamic repacking of the hydrophobic core. Acs Chem.Biol., 8, 2013
3I6X	Crystal structure of the calponin homology domain of IQGAP1 分子名称: Ras GTPase-activating-like protein IQGAP1 著者 Kurella, V.B. 登録日 2009-07-07 公開日 2010-07-21 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The IQGAP1 N-Terminus Forms Dimers, and the Dimer Interface Is Required for Binding F-Actin and Calcium-Bound Calmodulin. Biochemistry, 55, 2016
7U5V	Crystal structure of the Mixed Lineage Leukaemia (MLL1) SET Domain with the cofactor product S-Adenosylhomocysteine and Borealin peptide 分子名称: Borealin, Histone-lysine N-methyltransferase 2A, S-ADENOSYL-L-HOMOCYSTEINE, ... 著者 An, S, Cho, U.S, Oh, H, Sha, L, Xu, J, Kim, S, Yang, W, An, W, Dou, Y. 登録日 2022-03-02 公開日 2023-09-27 最終更新日 2024-04-10 実験手法 X-RAY DIFFRACTION (2.59 Å) 主引用文献 Non-canonical MLL1 activity regulates centromeric phase separation and genome stability. Nat.Cell Biol., 25, 2023
3IHQ	Crystal Structure of Reduced C10S Spx in Complex with the Alpha C-terminal Domain of RNA Polymeras 分子名称: DNA-directed RNA polymerase subunit alpha, IMIDAZOLE, Regulatory protein spx 著者 Newberry, K.J, Brennan, R.G. 登録日 2009-07-30 公開日 2010-02-02 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Promoter recognition by a complex of Spx and the C-terminal domain of the RNA polymerase alpha subunit. Plos One, 5, 2010
3LQH	Crystal structure of MLL1 PHD3-Bromo in the free form 分子名称: Histone-lysine N-methyltransferase MLL, ZINC ION 著者 Wang, Z, Patel, D.J. 登録日 2010-02-09 公開日 2010-07-07 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression. Cell(Cambridge,Mass.), 141, 2010
5F6L	The crystal structure of MLL1 (N3861I/Q3867L) in complex with RbBP5 and Ash2L 分子名称: Histone-lysine N-methyltransferase 2A, Retinoblastoma-binding protein 5, S-ADENOSYL-L-HOMOCYSTEINE, ... 著者 Li, Y, Lei, M, Chen, Y. 登録日 2015-12-06 公開日 2016-02-24 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural basis for activity regulation of MLL family methyltransferases. Nature, 530, 2016
5F5E	The Crystal Structure of MLL1 SET domain with N3816I/Q3867L mutation 分子名称: Histone-lysine N-methyltransferase 2A, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION 著者 Li, Y, Lei, M, Chen, Y. 登録日 2015-12-04 公開日 2016-02-24 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.802 Å) 主引用文献 Structural basis for activity regulation of MLL family methyltransferases. Nature, 530, 2016
6EMQ	Solution structure of the LEDGF/p75 IBD - MLL1 (aa 111-160) complex 分子名称: PC4 and SFRS1-interacting protein,Histone-lysine N-methyltransferase 2A 著者 Veverka, V. 登録日 2017-10-03 公開日 2018-08-01 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
2YJ7	Crystal structure of a hyperstable protein from the Precambrian period 分子名称: LPBCA THIOREDOXIN, SODIUM ION 著者 Gavira, J.A, Ingles, A, Ibarra, B, Garcia-Ruiz, J.M. 登録日 2011-05-19 公開日 2012-05-30 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Conservation of Protein Structure Over Four Billion Years Structure, 21, 2013
5NPL	Crystal structure of hexameric CBS-CP12 protein from bloom-forming cyanobacteria, Yb-derivative at 2.8 A resolution 分子名称: 10-((2R)-2-HYDROXYPROPYL)-1,4,7,10-TETRAAZACYCLODODECANE 1,4,7-TRIACETIC ACID, Similar to tr|Q8YYT1|Q8YYT1, YTTERBIUM (III) ION 著者 Hackenberg, C, Hakanpaa, J, Antonyuk, S.V, Dittmann, E, Lamzin, V.S. 登録日 2017-04-17 公開日 2018-05-30 最終更新日 2018-07-11 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 Structural and functional insights into the unique CBS-CP12 fusion protein family in cyanobacteria. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
8Z61	Human beta-catenin crystal structure 分子名称: Catenin beta-1 著者 Tim, F. 登録日 2024-04-18 公開日 2024-05-08 最終更新日 2024-08-21 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Discovery of Novel 1-Phenylpiperidine Urea-Containing Derivatives Inhibiting beta-Catenin/BCL9 Interaction and Exerting Antitumor Efficacy through the Activation of Antigen Presentation of cDC1 Cells. J.Med.Chem., 67, 2024
8Z0U	Human beta-catenin crystal structure 分子名称: Catenin beta-1 著者 Tim, F. 登録日 2024-04-10 公開日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Crystal protein human Beta-catenin To Be Published
8Y14	Beta-catenin Crystal Structure 分子名称: Catenin beta-1 著者 Tim, F. 登録日 2024-01-23 公開日 2024-03-13 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Beta-catenin Crystal Structure To Be Published
8Y0G	Human beta-catenin crystal structure 分子名称: Catenin beta-1 著者 Tim, F. 登録日 2024-01-22 公開日 2024-03-13 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal protein of human Beta-catenin To Be Published
8Z10	Human beta-catenin crystal structure 分子名称: Catenin beta-1, PROLINE 著者 Tim, F. 登録日 2024-04-10 公開日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Crystal structure of Beta-catenin To Be Published
8Z5J	Beta-catenin Crystal Structure 分子名称: Catenin beta-1 著者 Tim, F. 登録日 2024-04-18 公開日 2024-05-22 最終更新日 2024-08-21 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Discovery of Novel 1-Phenylpiperidine Urea-Containing Derivatives Inhibiting beta-Catenin/BCL9 Interaction and Exerting Antitumor Efficacy through the Activation of Antigen Presentation of cDC1 Cells. J.Med.Chem., 67, 2024
8Y0P	Beta-Catenin in complex with peptide 301 分子名称: B-cell CLL/lymphoma 9 protein, Catenin beta-1, PROLINE 著者 Tim, F. 登録日 2024-01-22 公開日 2024-04-17 実験手法 X-RAY DIFFRACTION (2.62 Å) 主引用文献 Beta-Catenin in complex with peptide 301 To Be Published
4N82	X-ray crystal structure of Streptococcus sanguinis NrdIox 分子名称: FLAVIN MONONUCLEOTIDE, Ribonucleotide reductase, SULFATE ION 著者 Boal, A.K, Rosenzweig, A.C. 登録日 2013-10-16 公開日 2014-01-08 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Streptococcus sanguinis Class Ib Ribonucleotide Reductase: HIGH ACTIVITY WITH BOTH IRON AND MANGANESE COFACTORS AND STRUCTURAL INSIGHTS. J.Biol.Chem., 289, 2014
4NW3	Crystal structure of MLL CXXC domain in complex with a CpG DNA 分子名称: 5'-D(*GP*CP*CP*AP*TP*CP*GP*AP*TP*GP*GP*C)-3', Histone-lysine N-methyltransferase 2A, ZINC ION 著者 Bian, C, Tempel, W, Chao, X, Walker, J.R, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) 登録日 2013-12-05 公開日 2014-04-23 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.82 Å) 主引用文献 DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants. Structure, 26, 2018
2YNX	Crystal Structure of Ancestral Thioredoxin Relative to Last Archaea Common Ancestor (LACA) from the Precambrian Period 分子名称: ACETATE ION, LACA THIOREDOXIN, SODIUM ION 著者 Gavira, J.A, Ingles-Prieto, A, Ibarra-Molero, B, Sanchez-Ruiz, J.M. 登録日 2012-10-19 公開日 2013-08-21 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.749 Å) 主引用文献 Conservation of Protein Structure Over Four Billion Years Structure, 21, 2013
4N83	X-ray crystal structure of Streptococcus sanguinis dimanganese(II)-NrdF 分子名称: MANGANESE (II) ION, Ribonucleoside-diphosphate reductase subunit beta 著者 Boal, A.K, Rosenzweig, A.C. 登録日 2013-10-16 公開日 2014-01-08 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Streptococcus sanguinis Class Ib Ribonucleotide Reductase: HIGH ACTIVITY WITH BOTH IRON AND MANGANESE COFACTORS AND STRUCTURAL INSIGHTS. J.Biol.Chem., 289, 2014
2YOI	Crystal Structure of Ancestral Thioredoxin Relative to Last Eukaryotes Common Ancestor (LECA) from the Precambrian Period 分子名称: ACETATE ION, CHLORIDE ION, LECA THIOREDOXIN, ... 著者 Gavira, J.A, Ingles-Prieto, A, Ibarra-Molero, B, Sanchez-Ruiz, J.M. 登録日 2012-10-24 公開日 2013-08-21 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Conservation of protein structure over four billion years. Structure, 21, 2013
2YN1	Crystal Structure of Ancestral Thioredoxin Relative to Last Gamma- Proteobacteria Common Ancestor (LGPCA) from the Precambrian Period 分子名称: LGPCA THIOREDOXIN, TRIETHYLENE GLYCOL 著者 Gavira, J.A, Ingles-Prieto, A, Ibarra-Molero, B, Sanchez-Ruiz, J.M. 登録日 2012-10-11 公開日 2013-08-21 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Conservation of Protein Structure Over Four Billion Years Structure, 21, 2013

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