6ZOJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6zoj by Molmil](/molmil-images/mine/6zoj) | SARS-CoV-2-Nsp1-40S complex, composite map | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Schubert, K, Karousis, E.D, Jomaa, A, Scaiola, A, Echeverria, B, Gurzeler, L.-A, Leibundgut, M.L, Thiel, V, Muehlemann, O, Ban, N. | 登録日 | 2020-07-07 | 公開日 | 2020-07-22 | 最終更新日 | 2021-02-10 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation. Nat.Struct.Mol.Biol., 27, 2020
|
|
6G5I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6g5i by Molmil](/molmil-images/mine/6g5i) | Cryo-EM structure of a late human pre-40S ribosomal subunit - State R | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. | 登録日 | 2018-03-29 | 公開日 | 2018-06-06 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Visualizing late states of human 40S ribosomal subunit maturation. Nature, 558, 2018
|
|
7K5I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7k5i by Molmil](/molmil-images/mine/7k5i) | |
4ETS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ets by Molmil](/molmil-images/mine/4ets) | |
7PMK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7pmk by Molmil](/molmil-images/mine/7pmk) | S. cerevisiae replisome-SCF(Dia2) complex bound to double-stranded DNA (conformation I) | 分子名称: | Cell division control protein 45,Cell division control protein 45, Chromosome segregation in meiosis protein 3, DNA helicase, ... | 著者 | Jenkyn-Bedford, M, Yeeles, J.T.P, Deegan, T.D. | 登録日 | 2021-09-02 | 公開日 | 2021-11-10 | 最終更新日 | 2022-02-02 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | A conserved mechanism for regulating replisome disassembly in eukaryotes. Nature, 600, 2021
|
|
7PMN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7pmn by Molmil](/molmil-images/mine/7pmn) | S. cerevisiae replisome-SCF(Dia2) complex bound to double-stranded DNA (conformation II) | 分子名称: | Cell division control protein 45,Cell division control protein 45, Chromosome segregation in meiosis protein 3, DNA polymerase alpha-binding protein, ... | 著者 | Jenkyn-Bedford, M, Yeeles, J.T.P, Deegan, T.D. | 登録日 | 2021-09-02 | 公開日 | 2021-11-10 | 最終更新日 | 2022-01-26 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | A conserved mechanism for regulating replisome disassembly in eukaryotes. Nature, 600, 2021
|
|
8IFE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ife by Molmil](/molmil-images/mine/8ife) | Arbekacin-added human 80S ribosome | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | 著者 | Tomono, J, Asano, K, Chiashi, T, Tanaka, Y, Yokoyama, T. | 登録日 | 2023-02-17 | 公開日 | 2024-02-14 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.57 Å) | 主引用文献 | Direct visualization of ribosomes in the cell-free system revealed the functional evolution of aminoglycoside. J.Biochem., 175, 2024
|
|
8IFD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ifd by Molmil](/molmil-images/mine/8ifd) | Dibekacin-added human 80S ribosome | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | 著者 | Tomono, J, Asano, K, Chiashi, T, Tanaka, Y, Yokoyama, T. | 登録日 | 2023-02-17 | 公開日 | 2024-02-14 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.59 Å) | 主引用文献 | Direct visualization of ribosomes in the cell-free system revealed the functional evolution of aminoglycoside. J.Biochem., 175, 2024
|
|
8PPK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ppk by Molmil](/molmil-images/mine/8ppk) | Bat-Hp-CoV Nsp1 and eIF1 bound to the human 40S small ribosomal subunit | 分子名称: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Schubert, K, Karousis, E.D, Ban, I, Lapointe, C.P, Leibundgut, M, Baeumlin, E, Kummerant, E, Scaiola, A, Schoenhut, T, Ziegelmueller, J, Puglisi, J.D, Muehlemann, O, Ban, N. | 登録日 | 2023-07-07 | 公開日 | 2023-10-18 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.98 Å) | 主引用文献 | Universal features of Nsp1-mediated translational shutdown by coronaviruses. Mol.Cell, 83, 2023
|
|
8PPL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ppl by Molmil](/molmil-images/mine/8ppl) | MERS-CoV Nsp1 bound to the human 43S pre-initiation complex | 分子名称: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Schubert, K, Karousis, E.D, Ban, I, Lapointe, C.P, Leibundgut, M, Baeumlin, E, Kummerant, E, Scaiola, A, Schoenhut, T, Ziegelmueller, J, Puglisi, J.D, Muehlemann, O, Ban, N. | 登録日 | 2023-07-07 | 公開日 | 2023-10-18 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.65 Å) | 主引用文献 | Universal features of Nsp1-mediated translational shutdown by coronaviruses. Mol.Cell, 83, 2023
|
|
6Y2L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6y2l by Molmil](/molmil-images/mine/6y2l) | Structure of human ribosome in POST state | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ... | 著者 | Bhaskar, V, Schenk, A.D, Cavadini, S, von Loeffelholz, O, Natchiar, S.K, Klaholz, B.P, Chao, J.A. | 登録日 | 2020-02-16 | 公開日 | 2020-04-15 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Dynamics of uS19 C-Terminal Tail during the Translation Elongation Cycle in Human Ribosomes. Cell Rep, 31, 2020
|
|
8G5Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8g5y by Molmil](/molmil-images/mine/8g5y) | mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state) | 分子名称: | 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ... | 著者 | Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C. | 登録日 | 2023-02-14 | 公開日 | 2023-04-19 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (2.29 Å) | 主引用文献 | mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
|
|
8G6J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8g6j by Molmil](/molmil-images/mine/8g6j) | mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state 2) | 分子名称: | (3R,6R,9S,12S,15S,18S,20R,24aR)-6-[(2S)-butan-2-yl]-3,12-bis[(1R)-1-hydroxy-2-methylpropyl]-8,9,11,17,18-pentamethyl-15-[(2S)-2-methylbutyl]hexadecahydropyrido[1,2-a][1,4,7,10,13,16,19]heptaazacyclohenicosine-1,4,7,10,13,16,19(21H)-heptone, (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine, 1,4-DIAMINOBUTANE, ... | 著者 | Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C. | 登録日 | 2023-02-15 | 公開日 | 2023-04-19 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
|
|
8GLP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8glp by Molmil](/molmil-images/mine/8glp) | mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus LSU focused refined structure) | 分子名称: | 1,4-DIAMINOBUTANE, 18S rRNA, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | 著者 | Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Watson, Z.L, Altman, R.B, Blanchard, S.C. | 登録日 | 2023-03-22 | 公開日 | 2023-04-19 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (1.67 Å) | 主引用文献 | mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
|
|
8G61
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8g61 by Molmil](/molmil-images/mine/8g61) | mRNA decoding in human is kinetically and structurally distinct from bacteria (AC state) | 分子名称: | 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ... | 著者 | Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C. | 登録日 | 2023-02-14 | 公開日 | 2023-04-19 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (2.94 Å) | 主引用文献 | mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
|
|
6ZV6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6zv6 by Molmil](/molmil-images/mine/6zv6) | Human RIO1(kd)-StHA late pre-40S particle, structural state B (post 18S rRNA cleavage) | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Plassart, L, Shayan, R, Plisson-Chastang, C. | 登録日 | 2020-07-24 | 公開日 | 2021-05-12 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | The final step of 40S ribosomal subunit maturation is controlled by a dual key lock. Elife, 10, 2021
|
|
8G5Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8g5z by Molmil](/molmil-images/mine/8g5z) | mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state) | 分子名称: | 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ... | 著者 | Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C. | 登録日 | 2023-02-14 | 公開日 | 2023-04-19 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (2.64 Å) | 主引用文献 | mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
|
|
7ANE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ane by Molmil](/molmil-images/mine/7ane) | Leishmania Major mitochondrial ribosome | 分子名称: | 30S Ribosomal protein S17-like protein, 50S ribosomal protein L13-like protein, AKAP7_NLS domain-containing protein, ... | 著者 | Soufari, H, Waltz, F, Parrot, C, Bochler, A, Hashem, Y. | 登録日 | 2020-10-11 | 公開日 | 2021-06-23 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structure of the mature kinetoplastids mitoribosome and insights into its large subunit biogenesis. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
7PLO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7plo by Molmil](/molmil-images/mine/7plo) | H. sapiens replisome-CUL2/LRR1 complex | 分子名称: | Cell division control protein 45 homolog, Claspin, Cullin-2, ... | 著者 | Jones, M.J, Yeeles, J.T.P, Deegan, T.D, Jenkyn-Bedford, M. | 登録日 | 2021-09-01 | 公開日 | 2021-11-10 | 最終更新日 | 2023-10-18 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | A conserved mechanism for regulating replisome disassembly in eukaryotes. Nature, 600, 2021
|
|
5A2Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5a2q by Molmil](/molmil-images/mine/5a2q) | Structure of the HCV IRES bound to the human ribosome | 分子名称: | 18S RRNA, HCV IRES, MAGNESIUM ION, ... | 著者 | Quade, N, Leiundgut, M, Boehringer, D, Heuvel, J.v.d, Ban, N. | 登録日 | 2015-05-21 | 公開日 | 2015-07-15 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Cryo-Em Structure of Hepatitis C Virus Ires Bound to the Human Ribosome at 3.9 Angstrom Resolution Nat.Commun., 6, 2015
|
|
7T5P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7t5p by Molmil](/molmil-images/mine/7t5p) | Cryo-EM structure of human SIMC1-SLF2 complex | 分子名称: | SMC5-SMC6 complex localization factor protein 2, SUMO-interacting motif-containing protein 1 | 著者 | Maeda, S, Oravcova, M, Boddy, M.N, Otomo, T. | 登録日 | 2021-12-13 | 公開日 | 2022-12-07 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers. Elife, 11, 2022
|
|
7R4X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7r4x by Molmil](/molmil-images/mine/7r4x) | Cryo-EM reconstruction of the human 40S ribosomal subunit - Full map | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Pellegrino, S, Dent, K.C, Spikes, T, Warren, A.J. | 登録日 | 2022-02-09 | 公開日 | 2023-02-22 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.15 Å) | 主引用文献 | Cryo-EM reconstruction of the human 40S ribosomal subunit at 2.15 angstrom resolution. Nucleic Acids Res., 51, 2023
|
|
6QZP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6qzp by Molmil](/molmil-images/mine/6qzp) | High-resolution cryo-EM structure of the human 80S ribosome | 分子名称: | (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine, 18S rRNA (1740-MER), 28S rRNA (3773-MER), ... | 著者 | Natchiar, S.K, Myasnikov, A.G, Kratzat, H, Hazemann, I, Klaholz, B.P. | 登録日 | 2019-03-12 | 公開日 | 2019-04-24 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Visualization of chemical modifications in the human 80S ribosome structure. Nature, 551, 2017
|
|
6OVM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ovm by Molmil](/molmil-images/mine/6ovm) | |
6OVK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ovk by Molmil](/molmil-images/mine/6ovk) | |