PDB: 222415 件ウェブページステータス検索Chemie searchBIRD

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4N7M	Tailoring Small Molecules for an Allosteric Site on Procaspase-6 分子名称: 3-(pyrrolidin-1-yl)isoquinolin-1(2H)-one, Caspase-6, PHOSPHATE ION 著者 Murray, J.M, Steffek, M. 登録日 2013-10-15 公開日 2013-12-18 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.125 Å) 主引用文献 Tailoring small molecules for an allosteric site on procaspase-6. Chemmedchem, 9, 2014
4N82	X-ray crystal structure of Streptococcus sanguinis NrdIox 分子名称: FLAVIN MONONUCLEOTIDE, Ribonucleotide reductase, SULFATE ION 著者 Boal, A.K, Rosenzweig, A.C. 登録日 2013-10-16 公開日 2014-01-08 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Streptococcus sanguinis Class Ib Ribonucleotide Reductase: HIGH ACTIVITY WITH BOTH IRON AND MANGANESE COFACTORS AND STRUCTURAL INSIGHTS. J.Biol.Chem., 289, 2014
4MWT	Crystal structure of human PPCA (trigonal crystal form 2) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Lysosomal protective protein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Kolli, N, Garman, S.C. 登録日 2013-09-25 公開日 2014-03-12 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (3.85 Å) 主引用文献 Proteolytic activation of human cathepsin A. J.Biol.Chem., 289, 2014
4MUM	Crystal structure of mitochondrial 5'(3')-deoxy ribonucleotidase alternative spliced variant 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Pachl, P, Rezacova, P. 登録日 2013-09-22 公開日 2014-02-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.271 Å) 主引用文献 Kinetic and structural characterization of an alternatively spliced variant of human mitochondrial 5'(3')-deoxyribonucleotidase. J Enzyme Inhib Med Chem, 30, 2015
4MY4	Crystal structure of phosphoglycerate mutase from Staphylococcus aureus. 分子名称: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, MANGANESE (II) ION 著者 Roychowdhury, A, Kundu, A, Gujar, A, Bose, M, Das, A.K. 登録日 2013-09-27 公開日 2013-10-16 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Complete catalytic cycle of cofactor-independent phosphoglycerate mutase involves a spring-loaded mechanism Febs J., 282, 2015
4N3S	Crystal structure of eukaryotic translation initiation factor eIF5B (399-852) from Saccharomyces cerevisiae, apo form 分子名称: 1,2-ETHANEDIOL, Eukaryotic translation initiation factor 5B, GLYCEROL 著者 Kuhle, B, Ficner, R. 登録日 2013-10-07 公開日 2014-07-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.832 Å) 主引用文献 eIF5B employs a novel domain release mechanism to catalyze ribosomal subunit joining. Embo J., 33, 2014
4N4G	Crystal structure of the Bromo-PWWP of the mouse zinc finger MYND-type containing 11 isoform alpha 分子名称: PHOSPHATE ION, ZINC ION, Zinc finger MYND domain-containing protein 11 著者 Li, Y, Ren, Y, Li, H. 登録日 2013-10-08 公開日 2014-03-05 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.947 Å) 主引用文献 ZMYND11 links histone H3.3K36me3 to transcription elongation and tumour suppression Nature, 508, 2014
4NGF	Structure of human Dicer Platform-PAZ-Connector Helix cassette in complex with 17-mer siRNA having 5'-p and UU-3' ends (3.1 Angstrom resolution) 分子名称: 5'-R(P*UP*CP*GP*AP*AP*GP*GP*UP*CP*CP*UP*UP*CP*GP*UP*UP*U)-3', Endoribonuclease Dicer 著者 Simanshu, D.K, Tian, Y, Patel, D.J. 登録日 2013-11-01 公開日 2014-03-05 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.101 Å) 主引用文献 A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer. Mol.Cell, 53, 2014
4NIN	DSVISLS segment 101-107 from Human Superoxide Dismutase 分子名称: DSVISLS segment from Superoxide dismutase [Cu-Zn], ZINC ION 著者 Sievers, S.A, Sawaya, M.R, Eisenberg, D. 登録日 2013-11-06 公開日 2013-12-04 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.402 Å) 主引用文献 Aggregation-triggering segments of SOD1 fibril formation support a common pathway for familial and sporadic ALS. Proc.Natl.Acad.Sci.USA, 111, 2014
4NIY	Crystal structure of trypsiligase (K60E/N143H/Y151H/D189K trypsin) complexed to YRH-ecotin (M84Y/M85R/A86H ecotin) 分子名称: CALCIUM ION, Cationic trypsin, Ecotin, ... 著者 Schoepfel, M, Parthier, C, Stubbs, M.T. 登録日 2013-11-08 公開日 2014-02-19 最終更新日 2014-03-19 実験手法 X-RAY DIFFRACTION (2.84 Å) 主引用文献 N-terminal protein modification by substrate-activated reverse proteolysis. Angew.Chem.Int.Ed.Engl., 53, 2014
4NQ5	Bacillus cereus Zn-dependent metallo-beta-lactamase at pH 7 complexed with compound CS319 分子名称: (3R,5R,7aS)-5-(sulfanylmethyl)tetrahydro[1,3]thiazolo[4,3-b][1,3]thiazole-3-carboxylic acid, Beta-lactamase 2, POTASSIUM ION, ... 著者 Gonzalez, J.M, Gonzalez, M.M, Vila, A.J. 登録日 2013-11-23 公開日 2014-11-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Inhibition of metallo-lactamases with bicyclic compounds TO BE PUBLISHED
4NR6	Crystal structure of the bromodomain of human CREBBP in complex with an oxazepin ligand 分子名称: 1-[7-(3,4-dimethoxyphenyl)-9-{[(3R)-1-methylpiperidin-3-yl]methoxy}-2,3-dihydro-1,4-benzoxazepin-4(5H)-yl]propan-1-one, CREB-binding protein 著者 Filippakopoulos, P, Picaud, S, Felletar, I, Hay, D, Fedorov, O, Martin, S, Chaikuad, A, von Delft, F, Brennan, P, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2013-11-26 公開日 2013-12-18 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 Crystal structure of the bromodomain of human CREBBP in complex with an oxazepin ligand To be Published
4NRI	Crystal Structure of a human Mms2/Ubc13 A122G mutant 分子名称: GLYCEROL, Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2 著者 Hodge, C.D, Edwards, R.A, Glover, J.N.M. 登録日 2013-11-26 公開日 2014-12-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Stochastic gate dynamics regulate the catalytic activity of ubiquitination enzymes. J.Am.Chem.Soc., 136, 2014
4NTF	Mus Musculus LTC4 synthase in S-hexyl-GSH complex form 分子名称: Leukotriene C4 synthase, NICKEL (II) ION, PALMITIC ACID, ... 著者 Niegowski, D, Rinaldo-Matthis, A, Haeggstrom, J.Z. 登録日 2013-12-02 公開日 2015-01-14 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 To be published To be Published
4NVK	Predicting protein conformational response in prospective ligand discovery. 分子名称: Cytochrome c peroxidase, N~2~,N~2~-diethylquinazoline-2,4-diamine, PHOSPHATE ION, ... 著者 Fischer, M, Fraser, J.S. 登録日 2013-12-05 公開日 2013-12-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.56 Å) 主引用文献 Incorporation of protein flexibility and conformational energy penalties in docking screens to improve ligand discovery. Nat Chem, 6, 2014
4NWQ	Computationally Designed Two-Component Self-Assembling Tetrahedral Cage, T33-21, Crystallized in Space Group F4132 分子名称: Putative uncharacterized protein PH0671, SULFATE ION, Uncharacterized protein 著者 McNamara, D.E, King, N.P, Bale, J.B, Sheffler, W, Baker, D, Yeates, T.O. 登録日 2013-12-06 公開日 2014-05-28 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Accurate design of co-assembling multi-component protein nanomaterials. Nature, 510, 2014
4NGT	Crystal Structure of Glutamate Carboxypeptidase II in a complex with urea-based inhibitor 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Tykvart, J, Pachl, P. 登録日 2013-11-02 公開日 2014-06-18 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Rational design of urea-based glutamate carboxypeptidase II (GCPII) inhibitors as versatile tools for specific drug targeting and delivery. Bioorg.Med.Chem., 22, 2014
4NEX	Structure of the N-acetyltransferase domain of X. fastidiosa NAGS/K 分子名称: Acetylglutamate kinase, N-ACETYL-L-GLUTAMATE, SULFATE ION 著者 Zhao, G, Jin, Z, Allewell, N.M, Tuchman, M, Shi, D. 登録日 2013-10-30 公開日 2014-11-12 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.6955 Å) 主引用文献 Structures of the N-acetyltransferase domain of Xylella fastidiosaN-acetyl-L-glutamate synthase/kinase with and without a His tag bound to N-acetyl-L-glutamate. Acta Crystallogr F Struct Biol Commun, 71, 2015
4NIO	GVTGIAQ segment 147-153 from Human Superoxide Dismutase with I149T mutation associated with a familial form of amyotrophic lateral sclerosis 分子名称: GVTGIAQ segment from Superoxide dismutase [Cu-Zn] 著者 Sievers, S.A, Sawaya, M.R, Eisenberg, D, Ivanova, M.I. 登録日 2013-11-06 公開日 2013-12-04 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Aggregation-triggering segments of SOD1 fibril formation support a common pathway for familial and sporadic ALS. Proc.Natl.Acad.Sci.USA, 111, 2014
4NGP	Crystal Structure of Glutamate Carboxypeptidase II in a complex with urea-based inhibitor 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Tykvart, J, Pachl, P. 登録日 2013-11-02 公開日 2014-06-18 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Rational design of urea-based glutamate carboxypeptidase II (GCPII) inhibitors as versatile tools for specific drug targeting and delivery. Bioorg.Med.Chem., 22, 2014
4NHD	Crystal structure of beta-ketoacyl-ACP synthase III (FabH) from Vibrio Cholerae in complex with Coenzyme A 分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 3 protein 1, CALCIUM ION, COENZYME A, ... 著者 Hou, J, Zheng, H, Langner, K, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2013-11-04 公開日 2013-12-25 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Crystal structure of beta-ketoacyl-ACP synthase III (FabH) from Vibrio Cholerae in complex with Coenzyme A To be Published
4NKL	Crystal structure of Staphylococcal nuclease variant Delta+PHS V66A/I92Q at cryogenic temperature 分子名称: CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease 著者 Caro, J.A, Sorenson, J.L, Schlessman, J.L, Heroux, A, Garcia-Moreno E, B. 登録日 2013-11-12 公開日 2013-11-20 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Pressure effects in proteins To be Published
4NMZ	Crystal structure of Staphylococcal nuclease variant Delta+PHS V23Q/V66A at cryogenic temperature 分子名称: CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease 著者 Caro, J.A, Sorenson, J.L, Schlessman, J.L, Heroux, A, Garcia-Moreno E, B. 登録日 2013-11-15 公開日 2013-12-11 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Cavities in proteins To be Published
4NNG	Structural basis for targeting the ribosomal protein S1 of Mycobacterium tuberculosis by pyrazinamide 分子名称: 30S ribosomal protein S1 著者 Yang, J, Liu, Y, Cai, Q, Lin, D. 登録日 2013-11-18 公開日 2014-12-24 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Structural basis for targeting the ribosomal protein S1 of Mycobacterium tuberculosis by pyrazinamide. Mol.Microbiol., 95, 2015
4NRD	Crystal structure of a putative GDSL-like lipase (BACOVA_04955) from Bacteroides ovatus ATCC 8483 at 2.10 A resolution 分子名称: 1,2-ETHANEDIOL, Uncharacterized protein 著者 Joint Center for Structural Genomics (JCSG) 登録日 2013-11-26 公開日 2013-12-25 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of a hypothetical protein (BACOVA_04955) from Bacteroides ovatus ATCC 8483 at 2.10 A resolution To be published

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