4MWT
Crystal structure of human PPCA (trigonal crystal form 2)
Summary for 4MWT
Entry DOI | 10.2210/pdb4mwt/pdb |
Related | 1IVY 4MWS |
Descriptor | Lysosomal protective protein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total) |
Functional Keywords | cathepsin a, glycoprotein, serine protease, carboxypeptidase, protective protein, n-linked glycosylation, proteolytically activated form, lysosomal enzyme, hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 98561.33 |
Authors | Kolli, N.,Garman, S.C. (deposition date: 2013-09-25, release date: 2014-03-12, Last modification date: 2020-07-29) |
Primary citation | Kolli, N.,Garman, S.C. Proteolytic activation of human cathepsin A. J.Biol.Chem., 289:11592-11600, 2014 Cited by PubMed: 24599961DOI: 10.1074/jbc.M113.524280 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.85 Å) |
Structure validation
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