4MWT
Crystal structure of human PPCA (trigonal crystal form 2)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Lysosomal protective protein | polymer | 428 | 48655.6 | 2 | UniProt (P10619) Pfam (PF00450) In PDB | Homo sapiens (human) | Carboxypeptidase C, Carboxypeptidase L, Cathepsin A, Protective protein cathepsin A, PPCA, Protective protein for beta-galactosidase |
2 | C | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
3 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) |
Sequence modifications
A, B: 1 - 452 (UniProt: P10619)
PDB | External Database | Details |
---|---|---|
- | Tyr 291 | deletion |
- | Glu 292 | deletion |
- | Lys 293 | deletion |
- | Asp 294 | deletion |
- | Thr 295 | deletion |
- | Val 296 | deletion |
- | Val 297 | deletion |
- | Val 298 | deletion |
- | Gln 299 | deletion |
- | Asp 300 | deletion |
- | Leu 301 | deletion |
- | Gly 302 | deletion |
- | Asn 303 | deletion |
- | Ile 304 | deletion |
- | Phe 305 | deletion |
- | Thr 306 | deletion |
- | Arg 307 | deletion |
- | Leu 308 | deletion |
- | Pro 309 | deletion |
- | Leu 310 | deletion |
- | Lys 311 | deletion |
- | Arg 312 | deletion |
- | Met 313 | deletion |
- | Trp 314 | deletion |
- | His 315 | deletion |
- | Gln 316 | deletion |
- | Ala 317 | deletion |
- | Leu 318 | deletion |
- | Leu 319 | deletion |
- | Arg 320 | deletion |
His 453 | - | expression tag |
His 454 | - | expression tag |
His 455 | - | expression tag |
His 456 | - | expression tag |
His 457 | - | expression tag |
His 458 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 97311.2 | |
Branched | Number of molecules | 1 |
Total formula weight | 586.5 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 663.6 | |
All* | Total formula weight | 98561.3 |