4MWS
Crystal structure of human PPCA (trigonal crystal form 1)
Summary for 4MWS
Entry DOI | 10.2210/pdb4mws/pdb |
Related | 1IVY 4MWT |
Descriptor | Lysosomal protective protein, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | cathepsin a, glycoprotein, serine protease, carboxypeptidase, protective protein, n-linked glycosylation, proteolytically activated form, lysosomal enzyme, hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 99565.27 |
Authors | Kolli, N.,Garman, S.C. (deposition date: 2013-09-25, release date: 2014-03-12, Last modification date: 2023-09-20) |
Primary citation | Kolli, N.,Garman, S.C. Proteolytic activation of human cathepsin A. J.Biol.Chem., 289:11592-11600, 2014 Cited by PubMed: 24599961DOI: 10.1074/jbc.M113.524280 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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