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2RJT
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Crystal Structure Analysis of a Surface Entropy Reduction Mutant of S. pneumoniae FabF
分子名称: Beta-ketoacyl-ACP synthase II
著者Soisson, S.M, Parthasarathy, G, Becker, J.
登録日2007-10-15
公開日2008-01-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Surface-entropy reduction approaches to manipulate crystal forms of beta-ketoacyl acyl carrier protein synthase II from Streptococcus pneumoniae.
Acta Crystallogr.,Sect.D, 64, 2008
2R8V
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BU of 2r8v by Molmil
Native structure of N-acetylglutamate synthase from Neisseria gonorrhoeae
分子名称: ACETYL COENZYME *A, Putative acetylglutamate synthase
著者Shi, D, Sagar, V, Jin, Z, Yu, X, Caldovic, L, Morizono, H, Allewell, N.M, Tuchman, M.
登録日2007-09-11
公開日2008-01-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The crystal structure of N-acetyl-L-glutamate synthase from Neisseria gonorrhoeae provides insights into mechanisms of catalysis and regulation.
J.Biol.Chem., 283, 2008
2RBK
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BU of 2rbk by Molmil
X-ray Crystallographic Structures Show Conservation of a Trigonal-Bipyramidal Intermediate in a Phosphoryl-transfer Superfamily.
分子名称: MAGNESIUM ION, Putative uncharacterized protein, oxido(dioxo)vanadium
著者Lu, Z, Dunaway-Mariano, D, Allen, K.N.
登録日2007-09-19
公開日2008-04-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献The catalytic scaffold of the haloalkanoic acid dehalogenase enzyme superfamily acts as a mold for the trigonal bipyramidal transition state.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2H5M
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BU of 2h5m by Molmil
NMR Solution Structure of a GCN5-like putative N-acetyltransferase from Staphylococcus aureus complexed with acetyl-CoA. Northeast Structural Genomics Consortium Target ZR31
分子名称: ACETYL COENZYME *A, Acetyltransferase, GNAT family
著者Cort, J.R, Ramelot, T.A, Acton, T.B, Ma, L, Xiao, R.B, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG)
登録日2006-05-26
公開日2006-11-28
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure of an acetyl-CoA binding protein from Staphylococcus aureus representing a novel subfamily of GCN5-related N-acetyltransferase-like proteins
J.Struct.Funct.Genom., 9, 2008
2H84
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Crystal Structure of the C-terminal Type III Polyketide Synthase (PKS III) Domain of 'Steely1' (a Type I/III PKS Hybrid from Dictyostelium)
分子名称: HEXAETHYLENE GLYCOL, Steely1
著者Austin, M.B, Saito, T, Bowman, M.E, Haydock, S, Kato, A, Moore, B.S, Kay, R.R, Noel, J.P.
登録日2006-06-06
公開日2006-08-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Biosynthesis of Dictyostelium discoideum differentiation-inducing factor by a hybrid type I fatty acid-type III polyketide synthase.
Nat.Chem.Biol., 2, 2006
2RGK
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BU of 2rgk by Molmil
Functional annotation of Escherichia coli yihS-encoded protein
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Uncharacterized sugar isomerase yihS
著者Itoh, T, Mikami, B, Hashimoto, W, Murata, K.
登録日2007-10-03
公開日2008-08-26
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of YihS in complex with D-mannose: structural annotation of Escherichia coli and Salmonella enterica yihS-encoded proteins to an aldose-ketose isomerase
J.Mol.Biol., 377, 2008
2TSR
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THYMIDYLATE SYNTHASE FROM RAT IN TERNARY COMPLEX WITH DUMP AND TOMUDEX
分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE, TOMUDEX
著者Sotelo-Mundo, R.R, Ciesla, J, Dzik, J.M, Rode, W, Maley, F, Maley, G, Hardy, L.W, Montfort, W.R.
登録日1998-06-19
公開日1999-02-16
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structures of rat thymidylate synthase inhibited by Tomudex, a potent anticancer drug.
Biochemistry, 38, 1999
2R98
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Crystal Structure of N-acetylglutamate synthase (selenoMet substituted) from Neisseria gonorrhoeae
分子名称: ACETYL COENZYME *A, Putative acetylglutamate synthase
著者Shi, D, Sagar, V, Jin, Z, Yu, X, Caldovic, L, Morizono, H, Allewell, N.M, Tuchman, M.
登録日2007-09-12
公開日2008-01-15
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The crystal structure of N-acetyl-L-glutamate synthase from Neisseria gonorrhoeae provides insights into mechanisms of catalysis and regulation.
J.Biol.Chem., 283, 2008
3EAW
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BU of 3eaw by Molmil
Replacement of Val3 in Human Thymidylate Synthase Affects Its Kinetic Properties and Intracellular Stability
分子名称: 1,2-ETHANEDIOL, SULFATE ION, Thymidylate synthase
著者Huang, X, Gibson, L.M, Bell, B.J, Lovelace, L.L, Pena, M.M, Berger, F.G, Berger, S.H.
登録日2008-08-26
公開日2010-03-02
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Replacement of Val3 in human thymidylate synthase affects its kinetic properties and intracellular stability .
Biochemistry, 49, 2010
3EO4
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BU of 3eo4 by Molmil
The crystal structure of a domain from Methanocaldococcus jannaschii DSM 2661
分子名称: 1,2-ETHANEDIOL, 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
著者Tan, K, Hatzos, C, Freeman, L, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2008-09-26
公開日2008-10-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献The crystal structure of a domain from Methanocaldococcus jannaschii DSM 2661
To be Published
6GW3
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BU of 6gw3 by Molmil
Structure of TKS from Cannabis sativa in complex with CoA
分子名称: 3,5,7-trioxododecanoyl-CoA synthase, 3,5,7-trioxododecanoyl-CoA synthase,3,5,7-trioxododecanoyl-CoA synthase, COENZYME A, ...
著者Karuppiah, V, Leys, D.
登録日2018-06-21
公開日2019-10-09
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献Structure of a PKS class III from Cannabis sativa
To Be Published
3E60
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BU of 3e60 by Molmil
Crystal structure of 3-oxoacyl-(acyl carrier protein) synthase II from Bartonella henselae
分子名称: 3-oxoacyl-[acyl-carrier-protein ] synthase II, POTASSIUM ION
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2008-08-14
公開日2008-08-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of 3-oxoacyl-(acyl carrier protein) synthase II from Bartonella henselae
To be Published
3EF9
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BU of 3ef9 by Molmil
Replacement of Val3 in Human Thymidylate Synthase Affects Its Kinetic Properties and Intracellular Stability
分子名称: SULFATE ION, Thymidylate synthase
著者Huang, X, Gibson, L.M, Bell, B.J, Lovelace, L.L, Pena, M.M, Berger, F.G, Berger, S.H.
登録日2008-09-08
公開日2010-03-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Replacement of Val3 in human thymidylate synthase affects its kinetic properties and intracellular stability .
Biochemistry, 49, 2010
3EH0
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BU of 3eh0 by Molmil
Crystal Structure of LpxD from Escherichia coli
分子名称: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase
著者Bartling, C.M, Raetz, C.R.H.
登録日2008-09-11
公開日2009-08-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure and acyl chain selectivity of Escherichia coli LpxD, the N-acyltransferase of lipid A biosynthesis
Biochemistry, 48, 2009
3ELY
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Wesselsbron virus Methyltransferase in complex with AdoHcy
分子名称: DI(HYDROXYETHYL)ETHER, Methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Bollati, M, Milani, M, Ricagno, S, Mastrangelo, E, Bolognesi, M.
登録日2008-09-23
公開日2008-11-18
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Recognition of RNA Cap in the Wesselsbron Virus NS5 Methyltransferase Domain: Implications for RNA-Capping Mechanisms in Flavivirus
J.Mol.Biol., 385, 2009
3EGT
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BU of 3egt by Molmil
T. Brucei Farnesyl Diphosphate Synthase Complexed with Bisphosphonate BPH-722
分子名称: 1-(2,2-diphosphonoethyl)-3-(heptyloxy)pyridinium, Farnesyl pyrophosphate synthase, MAGNESIUM ION
著者Cao, R, Gao, Y, Robinson, H, Oldfield, E.
登録日2008-09-11
公開日2009-05-05
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Lipophilic bisphosphonates as dual farnesyl/geranylgeranyl diphosphate synthase inhibitors: an X-ray and NMR investigation.
J.Am.Chem.Soc., 131, 2009
3EMB
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BU of 3emb by Molmil
Wesselsbron virus Methyltransferase in complex with AdoMet and 7MeGpppG
分子名称: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, Methyltransferase, S-ADENOSYLMETHIONINE, ...
著者Bollati, M, Ricagno, S, Milani, M, Mastrangelo, E, Bolognesi, M.
登録日2008-09-24
公開日2008-11-18
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Recognition of RNA Cap in the Wesselsbron Virus NS5 Methyltransferase Domain: Implications for RNA-Capping Mechanisms in Flavivirus
J.Mol.Biol., 385, 2009
3ED7
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BU of 3ed7 by Molmil
Replacement of Val3 in Human Thymidylate Synthase Affects Its Kinetic Properties and Intracellular Stability
分子名称: SULFATE ION, Thymidylate synthase
著者Huang, X, Gibson, L.M, Bell, B.J, Lovelace, L.L, Pena, M.M, Berger, F.G, Berger, S.H.
登録日2008-09-02
公開日2010-03-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Replacement of Val3 in human thymidylate synthase affects its kinetic properties and intracellular stability .
Biochemistry, 49, 2010
3ENH
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BU of 3enh by Molmil
Crystal structure of Cgi121/Bud32/Kae1 complex
分子名称: HEXATANTALUM DODECABROMIDE, Putative O-sialoglycoprotein endopeptidase, Uncharacterized protein MJ0187
著者Neculai, D.
登録日2008-09-25
公開日2008-10-28
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Atomic Structure of the KEOPS Complex: An Ancient Protein Kinase-Containing Molecular Machine
Mol.Cell, 32, 2008
6GYJ
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BU of 6gyj by Molmil
Mouse thymidylate synthase crystal soaked in phenolphthalein
分子名称: 3,3-bis(4-hydroxyphenyl)-2-benzofuran-1-one, DIMETHYL SULFOXIDE, SULFATE ION, ...
著者Maj, P, Jarmula, A, Wilk, P, Weiss, M.S, Rode, W.
登録日2018-06-30
公開日2019-08-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Thymidylate synthase fragment screening
To be published
3ES9
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BU of 3es9 by Molmil
NADPH-Cytochrome P450 Reductase in an Open Conformation
分子名称: FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Hamdane, D, Xia, C, Im, S.-C, Zhang, H, Kim, J.-J, Waskell, L.
登録日2008-10-05
公開日2009-01-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structure and function of an NADPH-cytochrome P450 oxidoreductase in an open conformation capable of reducing cytochrome P450
J.Biol.Chem., 284, 2009
3EDW
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BU of 3edw by Molmil
Replacement of Val3 in Human Thymidylate Synthase Affects Its Kinetic Properties and Intracellular Stability
分子名称: SULFATE ION, Thymidylate synthase
著者Huang, X, Gibson, L.M, Bell, B.J, Lovelace, L.L, Pena, M.M, Berger, F.G, Berger, S.H.
登録日2008-09-03
公開日2010-03-02
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Replacement of Val3 in human thymidylate synthase affects its kinetic properties and intracellular stability .
Biochemistry, 49, 2010
3EFQ
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T. Brucei Farnesyl Diphosphate Synthase Complexed with Bisphosphonate BPH-714
分子名称: 1-(2,2-diphosphonoethyl)-3-(octyloxy)pyridinium, Farnesyl pyrophosphate synthase, MAGNESIUM ION
著者Cao, R, Gao, Y, Robinson, H, Oldfield, E.
登録日2008-09-09
公開日2009-05-05
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Lipophilic bisphosphonates as dual farnesyl/geranylgeranyl diphosphate synthase inhibitors: an X-ray and NMR investigation.
J.Am.Chem.Soc., 131, 2009
3EUO
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BU of 3euo by Molmil
crystal structure of a fungal type III polyketide synthase, ORAS
分子名称: Type III Pentaketide Synthase
著者Zhang, H, Brunzelle, J.S, Nair, S.K.
登録日2008-10-10
公開日2008-11-04
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Distinct Structural Elements Dictate the Specificity of the Type III Pentaketide Synthase from Neurospora crassa.
Chem.Biol., 15, 2008
3EZA
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COMPLEX OF THE AMINO TERMINAL DOMAIN OF ENZYME I AND THE HISTIDINE-CONTAINING PHOSPHOCARRIER PROTEIN HPR FROM ESCHERICHIA COLI NMR, RESTRAINED REGULARIZED MEAN STRUCTURE
分子名称: HISTIDINE-CONTAINING PHOSPHOCARRIER PROTEIN HPR, PHOSPHOTRANSFERASE SYSTEM, ENZYME I
著者Clore, G.M, Garrett, D.S, Gronenborn, A.M.
登録日1998-11-03
公開日1999-05-25
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the 40,000 Mr phosphoryl transfer complex between the N-terminal domain of enzyme I and HPr.
Nat.Struct.Biol., 6, 1999

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